Your synergistic outsourcing solution Powered by CTB

™ Your synergistic outsourcing solution Powered by CTB Solutions, Inc Patent Pending

Organization • • • Tony Carita - CEO Marius Manole – CTO David Fenske – VP Business Delivery Andrea Bradbury –Quality Support Programming Support – Arobs 2

What is Syn. Source will facilitate successful management of: • Provider identification • Standardized RFI & RFP development • Centralized proposal submission with access to historical data • Automated comparative bid analysis • Facilitated negotiation • Contract development • Performance monitoring • Invoicing support tied to performance • Scope change management INNOVATION • Forecasting including real time updates based on actual study enrollment Flexible to meet individual study needs

Syn. Source Foundation RFI Closeout Changes RFP Service Type Invoicing Negotiation Contract Earned Value Forecasting 4

Syn. Source Menu Manage documents View direct report’s work stream RFI & vendor data RFP scoring negotiation Manage unit templates Manage forms Manage internal users & teams Manage providers Contracts earned value forecasting invoicing changes Creating synergy across your organization 5

Syn. Source Home Page Automatic system notifications Active documents Standard & customizable metrics 6

Syn. Source Summarizes • Financial. Forecasts • Instant access to top line forecast and projected spend • Easily group or sort 7

Syn. Source Summarizes • Performance Data • Establish variance thresholds and instantly access contracts that have variances • Instant access to Gantt charts 8

Projected Savings Activity Standard Practice Cost Syn. Source Home grown Excel file (bid grid) Separate Word doc for RFP/SOW Managing multiple revisions No historical or industry data Manual process to ensure consistency Internal system maintenance $15 -25 K per RFP • Integrated system for development of completed RFP (Bid Grid/SOW/RFP) • Auto-generated text • Collaborative document management RFP Development • • • Negotiation/ Contract Finalization • Manual process to compare • Limited manual access to historical data • Manual excel tracker to track offers • Manual look up of prior bids $15 -25 K per contract • • • Earned Value • Project plan manually entered in Excel and/or MS Project • Actual work performed manually entered and tracked each month • Data manually transmitted to teams 8 -12 hrs per project month • Integration allows negotiated contract data to automatically populate project plan/GANTT Chart • Plan vs. actual, remaining units and invoice detail automatically calculated based on units completed • Complete transparency to teams and between sponsor and provider Auto analysis of bids Facilitated negotiation process Tracks offers Access to historical data Central repository for negotiation records Savings 75 -80% 50 -60% 80 -90%

Projected Savings Activity Standard Practice Cost Syn. Source Savings Budget Forecasting • Manually track work performed against plan and calculate remaining work. • Manually forecast remaining work 8 -12 hrs per project month • Integration automates forecast based on earned value calculations & remaining work • Can tie forecasted to actual vs planned recruitment rates for dynamic forecasting 80 -90% Management of Invoices • Manually review and approve invoice detail • Manually resolve invoicing errors (10%) 1 -2 hrs per project month • Integration allows invoice detail to be autogenerated as an output of earned value • Automated process utilizing contract data eliminates errors 80 -90% Change in Scope Management Manually tracked in Excel 1 -2 hrs project month Change in scopes automatically tracked and incorporated into overall budget forecast 80 -90% Internal Reporting Manual process of rolling up study budgets, study forecasts and invoicing details. 10 -15 hrs month All of the study budget, forecast, performance and invoicing details can be immediately accessed and filtered to view many different data scenarios. 80 -90%

Saving Summary Activity Cost RFP Development $15 -25 k per RFP 75% 80% $11, 250. 00 $20, 000. 00 Negotiation/Contract Finalization $15 -25 k per RFP 50% 60% $7, 500. 00 $15, 000. 00 Earned Value 8 -12 hrs per project month 80% 90% $128. 00 $216. 00 Budget Forecasting 8 -12 hrs per project month 80% 90% $128. 00 $216. 00 Invoicing 1 -2 hrs per project month 80% 90% $16. 00 $36. 00 Change in Scope Management 1 -2 hrs per project month 80% 90% $120. 00 $270. 00 Internal Reporting 10 -15 hrs per month 80% 90% $1, 200. 00 $2, 700. 00 Monthly Yearly/Study 20 Studies & RFP Year 2 Year 3 Total 3 Years $452 $24, 174 $483, 480 $580, 176 $696, 211 $1, 759, 867 $873 $45, 476 $909, 520 $1, 091, 424 $1, 309, 709 $3, 310, 653 Notes: Savings Range 150 Hourly Rate 20% Annual Growth $ Savings Range 20 No of on-going Projects 20 No of RFPs

Hosting Our cloud hosting provides : • Rapid Scaling and Application Uptime: Easy to add/remove application servers to an existing pool of load balanced web servers to handle all incoming requests • Prevent Application Downtime: using f 5 load balancing internet traffic is spread across multiple web servers. In the event a server becomes unavailable, the load balancer will redirect all traffic to the remaining online servers 12

Backup Automated daily database backup • Database information is automatically backed-up daily. The backup is copied into the cloud storage onto multiredundant RAID 6 hard-drives and onto a second independent cloud provider Application backup image • Application server image is kept into the cloud storage for rapidly creating application servers. Time to deploy a new application server – less than 30 minutes 13

Technology Presentation level ASP. Net 4. 0 & Javascript- Base structure Silverlight 4 – Forms generator Dev. Express. Xtra. Reports– Reporting Business Logic & Data Access Layers ADO. NET Entity Framework Database Microsoft SQL Server 2008 14

Security Logical separation of individual sponsor databases Unique access/Domain login Permission based access by email and password 15

Why Syn. Source • • • An innovative product that will help your organization operate more effectively and efficiently Standardized templates that can easily be customized Work flow optimization Integrated bidding process to facilitate RFI/RFP development Reduced time from RFP to contract signature Tools that will improve performance measurement and invoicing accuracy tied to performance Access to historical data Automated budget forecasting tied to real time enrollment data Scope change management Flexibility to be easily user-customized during each step of the process. 16

Syn. Source Screen Shots 17

Syn. Source Setup Easilymanage : • • • Company profile Document templates & library Unit templates & library RFI/RFP/Review templates Internal users & permissions External providers Flexible to meet individual study needs 18

Syn. Source Setup Easilymanage: • Company profile • Document templates & library • Unit templates & library • RFI/RFP/Review templates • Internal users & permissions • External providers Flexible to meet individual study needs 19

Managing Unit Templates organized by service Create multiple templates for each service Create new templates from library or scratch 20

Syn. Source Setup Easilymanage: • Company profile • Document templates & library • • Unit templates & library RFI/RFP/Review templates Internal users & permissions External providers Flexible to meet individual study needs 21

Managing Documents organized by service type 22

Built in Document Review System templates can be: • Routed to teams for online group review • Simultaneous review • Automatic version control

Syn. Source Setup Easilymanage: • • Company profile Document templates & library Unit templates & library RFI/RFP/Review templates • Internal users & permissions • External providers Flexible to meet individual study needs 24

Managing Internal Users Easilymanage user roles and permissions 25

RFI Work Stream Create RFI Internal Review Receive and Review RFIs Finalize RFI Mine RFI Data Send to Providers

RFI Status • Create and send RFIs to multiple providers in minutes • Receive automatic notifications • System automatically tracks responses

RFI Reports Select fields of interest Create single or multiple filters Easily create custom reports 28

RFP Process Create RFP Receive RFPs Internal Review Finalize RFP Review and Rate RFP Responses Negotiate Send to Providers Award a Contract

RFP Work Stream RFP development is automated and includes: • Basic study information • Detailed budget grid by unit of work to be performed • System-generated detailed statement of work Flexible to meet individual study needs

RFP Work Stream • Create and send and RFP to multiple providers in minutes • Automated RFP review by sponsor team • Summary table details proposals against benchmark • Automated comparison/score of proposals • System-facilitated negotiation • Offers and counter-offers tracked

Proposal Review Functions Easily send proposals to study teams for evaluation Quickly schedule bid defense meetings Select bidder 32

Facilitated Negotiation • Instantly view – High and low bids – Sponsor and provider offers • Easily make new offer 33

Managing Contracts 34

Study Performance One click automated earned value reports including cost variance and balance of work

Invoicing • Payments can be based on - Milestones - Units completed - Mixed model • Pending invoices are auto-generated as providers complete study performance 36

Study Forecasting One click study forecasts with user defined: • Number of periods • Forecasting period (monthly, quarterly or yearly) Forecasting can be tied to real time enrollment data to dynamically reforecast budget and timeline based on actual vs planned enrollment.

Changes One click access to develop a change in scope 38

™ Syn. Source Defines Your Next Generation Outsourcing Solution Powered by CTB Solutions, Inc Patent Pending