Voltaren and Cataflam Tehran Iran Dr Narges Alavi

Voltaren and Cataflam Tehran, Iran Dr. Narges Alavi, Brand Manager

Agenda § Differentiation between Voltaren & Cataflam § Indications ( Acute & Chronic Pain) § Voltaren Messages § Cataflam Messages § Dosage forms § Prices 2 | Presentation Title | Presenter Name | Date | Subject | Business Use Only

Class - Diclofenac Sodium, a derivative of phenyl acetic acid.

Properties § Inhibits prostaglandin (PG) biosynthesis. PGs largely contribute to causation of inflammation, pain and fever. § A non-steroidal compound with pronounced antirheumatic, anti-inflammatory, analgesic and antipyretic properties. 5 | Presentation Title | Presenter Name | Date | Subject | Business Use Only

Voltaren In Rheumatic Disease Gives marked relief from: - Pain at rest. - Pain on movement. - Morning stiffness. - Swelling of joints. 2. Provides an improvement of function. 6 | Presentation Title | Presenter Name | Date | Subject | Business Use Only

Kinetics of the different dosage forms

Voltaren Indications in CHRONIC pain § Inflammatory and degenerative forms of rheumatism. § Rheumatoid arthritis. § Osteoarthritis & Spondylarthritis. § Juvenile Rheumatoid Arthritis. § Ankylosing Spondylitis. 8 | Presentation Title | Presenter Name | Date | Subject | Business Use Only

Voltaren Dosage § Ideal daily dose: 150 mg. § Long term Therapy: 75 -100 mg daily § In 2 - 3 fractional doses or once daily § Starting dose: 100 -150 mg daily (in milder cases: 75 -100 mg daily) 9 | Presentation Title | Presenter Name | Date | Subject | Business Use Only

Voltaren forms in Iran Voltaren Retard 100 mg Voltaren SR 75 mg Voltaren EC 50 mg

40 years More than billion patients use. In more than 140 countries

Voltaren Messages § Demonstrated in over 3900 trials which make it the standard reference drug for testing new NSAIDs. § Continues to demonstrate a favourable safety profile § Wide range of forms & strengths. § The original one from the house of NSAIDs. § Concentrations in synovial fluid are higher than concentrations in the plasma & remain higher for up to 12 hrs. § Has a strong analgesic effect. 12 | Presentation Title | Presenter Name | Date | Subject | Business Use Only

CATAFLAM

Cataflam Class It belongs to the NSAID’s class. “diclofenac potassium, a derivative of phenylacetic acid”. 14 | Presentation Title | Presenter Name | Date | Subject | Business Use Only

Cataflam Indications In ACUTE Pain § CATAFLAM will be positioned as the FAST RELIEF for Non-Rheumatic Pain indication 1. URTI 2. Sprain & Strain. 3. Dental Pain 4. Dysmenorrhea 15 | Presentation Title | Presenter Name | Date | Subject | Business Use Only

CATAFLAM Pharmacokinetics Mean Peak Plasma After AUC Protein Binding 3. 8 µmol/L reached in 20 -60 Half That of Injection 99. 7% (Chiefly to Albumin : 99. 4%) T 1/2 1 -2 h Site Of Inflammation 8 -12 h Excretion 16 Cataflam 50 | Business Use Only- Min 60% Urine 40% Faeces

Rapid Pain Relief observed within 10 minutes with Cataflam

Cataflam Dosage CATAFLAM 50 MG · 2 - 3 Tabs daily ( 100 – 150 mg) ( over 14 yrs ). · Before meals. · Forms: 20 tab 18 | Presentation Title | Presenter Name | Date | Subject | Business Use Only

Cataflam for ACUTE PAIN & RAPID Pain Relief

Voltaren & Cataflam Price list 20

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