VISION Uttar Pradesh to become more prosperous State

VISION Uttar Pradesh to become more prosperous State through utilizing modern tools of Science and Technology- bringing prosperity to farmers, generating employment in rural areas, food for all, Good health and clean environment.

Applications of Science and Technology have multiplied in recent times, touching every aspect of our lives. Advances made in communications, production technology, biotechnology, pharmaceuticals, medicine, space technology and so on have made a difference to the lives of most people. No doubt science has contributed to economic development of the country.

OBJECTIVES 1. To establish pre-eminent position of the State in the field of Science and Technology with particular reference to Biotechnology. 2. To improve and strengthen the infrastructure all over the State so that the benefits of the scientific and technological advances reaches to common man. 3. To develop scientific infrastructure for attracting industries to the State by providing common facilities for Safety evaluation & toxicity testing, Analytical facility for food processing industries, Drug development facility for use of SME. 4. To set up Bioindustrial Park, Pharma Biotech and Bio-IT Parks. 5. To set up an advance centre for research applications. 6. To promote research and development and establish centers of excellence in frontier area of biotechnology. 7. To generate Human Resource in emerging area of Science and Technology- Biotechnology, Genetic Engineering and Nanotechnology.

STRENGTHS UTTAR PRADESH AT A GLANCE Ø Uttar Pradesh - an agrarian State Ø Population – 167 million Ø Area: 240, 000 Km² Ø Capital – Lucknow, the city of Nawabs INDIA

… STRENGTHS Major Crops of Uttar Pradesh needing inputs of Biotechnology: Milk Sugarcane Potato Mango Wheat Amla Rice Maize • Uttar Pradesh is an agrarian State – Strength lies in its agriculture base • Uttar Pradesh No. 1 in production of Potato, Sugarcane and Amla

… STRENGTHS Advantage Uttar Pradesh Vidhan Sabha, U. P. Ø Capital of Uttar Pradesh. Ø Well connected by air, rail and road to the entire country. Ø Air connections to selected cities abroad by International Airport. Ø Wide network of roads and local transportation. Ø Century-plus tradition of education. Ø Diversity and Availability of Trained Manpower. Ø Low cost R&D facilities of 26 Scientific Institutions for Outsourcing Research Ø Over 400 Scientists, 700 Technicians and 500 Research Students Contd.

… STRENGTHS Advantage Uttar Pradesh Ø Several well recognized Universities and numerous Premier educational institutes in the State like Lucknow University, Banaras Hindu University, Aligarh Muslim University, Indian Institute of Technology at Kanpur & Roorkee, University of Roorkee, King George’s Medical University, Sanjay Gandhi PG Institute for Medical Sciences, etc. Sanjay Gandhi Post Graduate Institute (SGPGI) King George’s Medical University Lucknow University

… STRENGTHS Advantage Uttar Pradesh Ø Four Council for Scientific and Industrial Research (CSIR) Laboratories: Ø Central Drug Research Institute (CDRI) Ø Indian Institute of Toxicology Research (IITR) CDRI Ø Central Institute for Medicinal and Aromatic Plants (CIMAP) Ø National Botanical Research Institute (NBRI) ITRC Ø Three Indian Council of Agricultural Research (ICAR) Laboratories: Ø Central Institute for Sub-tropical Horticulture (CISH) NBRI Ø Indian Institute of Sugarcane Research (IISR) Ø National Bureau of Fish Genetic Resources (NBFGR) CIMAP NBFGR CISH IISR

… STRENGTHS Biotech Park, Lucknow

… STRENGTHS

… STRENGTHS Major Educational Institutions and Universities Ø Ø Ø Ø Ø Advanced Level Telecommunication Training Centre (ALTTC) Aligarh Muslim University (AMU) Allahabad University (AU) Banaras Hindu University (BHU) Birbal Sahni Institute of Palaeobotany Central Avian Research Institute (CARI) Central Drug Research Institute (CDRI) Central Institute for Research on Goats (CIRG) Central Institute of Higher Tibetan Studies (CIHTS) Central Institute of Medicinal and Aromatic Plants (CIMAP) Ch. Charan Singh University Chhatrapati Shahuji Maharaj Medical University Dr. Bhim Rao Ambedkar University Dr. Ram Manohar Lohiya National Law University, Lucknow Educational Consultants India Limited (EDCIL) Footwear Design and Development Institute (FDDI) Harcourt Butler Technological Institute

… STRENGTHS Major Educational Institutions and Universities Ø Ø Ø Ø Indian Institute of Information Technology, Allahabad (IIITA) Indian Institute of Management, Lucknow (IIML) Indian Institute of Pulses Research (IIPR) Indian Institute of Sugarcane Research (IISR) Indian Institute of Technology, Kanpur (IITK) Indian Institute of Vegetable Research (IIVR) Indian Veterinary Research Institute (IVRI) Indira Gandhi Rashtriya Uran Academy (IGRUA) Indian Institute of Toxicology Research (IITR) Institute of Judicial Training and Research (IJTR) Kamla Nehru Institute of Technology (KNIT) Kendriya Hindi Sansthan Madan Mohan Malaviya Engineering College (MMMEC) Mahatma Jyotiba Phule Rohilkhand University (MJPRU) Mehta Research Institute of Physics and Mathematical Physics Motilal Nehru National Institute of Technology (MNNIT), Allahabad

… STRENGTHS Major Educational Institutions and Universities Ø Narendra Deva University of Agriculture and Technology (NDUAT) Ø National Botanical Research Institute (NBRI) Ø National Institute for Entrepreneurship and Small Business Development (NIESBUD) Ø National Research Centre for Agroforestry (NRCAF) Ø National Sugar Institute Ø Power Management Institute (PMI) Ø Small Industries Service Institute (SISI), Kanpur Ø State Institute of Education Technology, Lucknow Ø Uttar Pradesh Education for All Project (UPEFA) Ø Uttar Pradesh Technical University (UPTU) Ø V. V. Giri National Labour Institute (VVGNLI) Ø Veer Bahadur Singh Purvanchal University

WEAKNESS Ø Over the years, the infrastructure of the scientific laboratories in the State Universities and institutions has deteriorated due to a lack of a goal oriented policy and visionary approach. Ø The institutes have not been able to deliver the products in terms of human resource and technologies which would find application in the field. This led to a low agricultural growth, low scientific output of papers and patents and little ecognition of scientists at national and international levels.

… WEAKNESS Ø The infrastructure is totally inadequate in comparison to other States. The State also lacks sustainability in terms of well identified programmes, their implementation and rigorous monitoring. Ø Also, there is very little utilization of the existing scientific infrastructure while drawing schemes in agriculture, horticulture and infrastructure development. Ø The scientific institutions owned by the State, State Universities and the Central Universities andnstitutions can play an important role if a mechanism is established and used.

OPPORTUNITIES Besides the core sectors of Science & Technology, the Government of India has chalked out policies supporting research in modern areas of Science and Technologies. Few Examples: Ø The budget of DBT over the next 5 years will increase by 450% and DBT will spend 30% of its budget on innovative projects in partnership with industry. Ø Recently announced National Biotechnology Development Strategy aims to: • Establish an Ecosystem of Innovation • Develop Quality Human Resource & Infrastructure • Promote R&D in Small and Medium Enterprises

…. OPPORTUNITIES Ø To achieve this Government has taken several initiatives, including setting up of Biotech Parks and incubators, enabling public institutions to work with industry, expansion of SBIRI scheme, etc. Ø The DBT has enhanced its budget for supporting the infrastructure facilities for drug discovery and drug development which includes setting up of national facilities in partnership with Government institutions and industry. Ø To promote Nanotechnology, a Nano Science and Technology Mission (NSTM), to make country a global hub for nanoscience and nanotechnology, has been setup, the objectives of which are • Basic Research Promotion • Infrastructure Development for Nano Science and Technology Research • Nano Applications and Technology Development Programmes • Human Resource Development • International Collaborations

…. OPPORTUNITIES Ø Department of Science and Technology (DST) is also setting up Nanotechnology R&D centres at Bangalore, Kolkata and Mohali Ø National Institute of Pharmaceutical Education and Research (NIPER), Mohali developing nanotechnology toxicity guidelines and a laboratory for toxicity of newly-developed drugs. Ø Central Scientific Instruments Organization (CSIO) devised microdiagnostics kits for TB Ø Defense Research and Development Establishment (DRDO), Gwalior developed a Typhoid detection kit NANO DEVICES Ø Development of one dose a day ciprofloxacin Ø Oral insulin formulation using nanoparticles carriers Ø Liposomal based Amphotericin B formulation

…. OPPORTUNITIES NANOTECHNOLOGY IN TEXTILES Ø Raymonds had a big hit with its nano-treated trousers and is now launching nano-shirts under the Park Avenue label Ø Ashima Group has exported over 1 million yards of nano-treated fabric to top retailers like Gap and Banana Republic Ø Arrow has launched stain-resistant Nanotechnology shirts in Mumbai NANOTECHNOLOGY IN FILTERATION Ø IIT-Madras has released a water purifier using nanotechnology. Technology used in the product is the very first and is home grown. No nanoparticle based water purifier exists in the world as of now. NANOTECHNOLOGY PARKS Likewise, CSIR and ICMR have also several schemes for supporting S&T in specified areas.

…. OPPORTUNITIES Ø The infrastructure development cost and support system cost in Uttar Pradesh are much lower than the States like Karnataka, Andhra, Maharastra and Gujarat. Therefore, industries are moving into the 2 nd tier States / cities where infrastructure is available and the Governments are providing incentives, concessions and playing a felicitator and catalytic role. Ø The ex-patriots, NRIs and the industries from USA and Europe are also exploring new destinations where they can access collaborations and get support for the establishment i. e. a single window mechanism for proccuring land, registration, licenses, etc. Ø The major interest worldwide is in the area of developing diagnostics particularly for infectious diseases, treatment of diabetes, cardiovascular, ageing, inflammatory reproductive ailments and neurological disorders. Ø Several companies are setting up CRO’s example Novo. Novartis, Genzyme, etc.

…. OPPORTUNITIES Ø The improved IPR and relaxation of FDI on one hand recognized expertise of Indian scientists as well as the quality control are other enabling factors to advance science and technology and their applications in industry. Ø Setting up of Biotech Park Lucknow has attracted 15 new companies of which five are of US origin. Big giants like Biocon, India recently approached Biotech Park for 20 acres of land to setup their R&D Center.

…. OPPORTUNITIES Ø Investors like International Biotechnology Invest Corporation, Boston, USA are keen to set up an Institute of Biopharma and Biotechnology and industrial biopharma Cluster in Lucknow. Ø Ansals Private, Limited are setting up SEZ for IT and Biotechnology Ø The State has a stable Government for five years and therefore, there is a high time to utilize science and technology for its development through a well chalked out road map.

THREATS Ø As the Uttar Pradesh is the largest and most populous State, it has the maximum number of young people i. e. a valuable human resource. This human resource is one of the factors attracting several developed countries towards India. However, if they are not adequately trained and gainfully employed or encouraged to setup their own industries, they will move out from the State. Already, due to lack of educational institutions offering courses in new disciplines, a majority of students are going out of the State to other States like Andhra, Karnataka, Maharastra, Gujarat, etc.

…THREATS Ø Other States have drawn and implemented industrial, biotechnology, nanotechnology policies for the States. These policies are being updated also. Ø Biotechnology Policy announced in 2004 by the Government of Uttar Pradesh not only needs to be updated but also implemented with the issue of necessary GO’s. The strength of State in major scientific institutions are not known all over the country and world as there is no sustained programme for showcasing the State Science and Technology strengths, commitments, policies, etc.

ROAD MAP 1. Human Resource Development All over the country there is dearth of talent and human resource in upcoming new areas • Biotechnology- biopharma, bioagri and industrial biotechnology • Information Technology- As applicable to drug development, toxicology, agriculture • Nanotechnology- drug diagnosis, sensors, etc. delivery, monitoring,

Human Resource Development Create institutions with scope of expansion e. g. Ø Institute of Biopharma and Biotechnology for Post Doctoral and Doctoral Training Ø Food Processing and Food Technology Ø Advance Centre for Research Application Set up an Advanced Centre for Research Application on lines of Jawahar Lal Nehru Centre for Advanced Scientific Research, Bangalore. It should provide facilities for innovative research in the emerging fields of genomics, proteomics, nanotechnology and biotechnology as applicable for over all upliftment of the State and providing good health and clean environment. Ø Centre for Transgenic Plants and Animals

Human Resource Development Ø National facility for Safety Evaluation of Biopharma and Biotech Products In North India adequate facilities for undertaking safety evaluation of biotech products is not available. With the setting up of Biotech Park, Lucknow and increasing activity in the Pharma Biotech sector, a large number of new products are being developed. Before introducing them into the market, generation of data on their safety / toxicity is essential. Ø Biotechnology Training Centres One centre be established at Lucknow utilizing expertise and facilities available with CSIR / ICAR laboratories. The other three centres be developed at Gorakhpur, Jhansi and Meerut or other places as per States priority Ø Institute 200 trainee fellowships like BCIL for training in biopharma, agritechnology and biotechnology, nanotechnology. The trainees be paid Rs. 8000/- p. m. and the industries Rs. 50, 000 p. a. National facility for Safety

2. Enabling and Translating Research Ø Set up technology incubators (atleast 5 by the end of this XIth Plan). v Common facilities for analysis, synthetic compounds, screening of biological activity, safety evaluation and toxicity testing. v Common facilities for separation of molecules, sequencing, preparation of molecular probes and production of proteins in bulk quantities. v Common facilities for genetic improvement, tissue culture, transgenic production

3. Enabling Industries Ø Set up Industrial Parks / Biotech Parks / Pharma Parks / IT Parks / Agri Parks and Food Parks v These should be set at places depending upon the existing strength and availability of raw material v These should be set up in partnership with the industries. The common facilities like analytical support, quality control support, etc. could be provided by the State / Central Government.

4. Promoting Science & Tech. for Rural Development The State has knowledge base institutions of excellence to develop as a bio-business hub in North India like Andhra, Karnataka, Maharastra and Gujarat. Inadequate scientific infrastructure for technology dissemination, demonstration and utilization at divisional and district levels has limited the growth of science and technology in the State and adoption of scientific leads. Set up 17 bio centres, one (anywhere) in each division on easily sparable land of UPSIDC industrial estates – The one of Lucknow division be established in Lucknow Industrial Development Authority (LIDA) in an area of 250 acres.

VISION GROUP / STRATEGY PLANNING GROUP / STEERING COMMITTEE To achieve the road map a strategy planning group consisting the top most scientific and technical experts, administration and industry is essential. The following is proposed Ø Chairman: Top most scientist of the country Ø Experts – 10 (7 from India and 3 from Abroad) (Top scientists from institutions both Government and industries) 6 Basic, 2 clinical, 2 agri Ø Convener – Chief Secretary Ø Member Secretary (Principal Secretary / Secretary, Science and Technology) Ø Implementing Agency (Department of Science and Technology / CST, U. P. )