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Ústavní schůzka Pondělí 5. ledna 2015 Ústavní schůzka Pondělí 5. ledna 2015

Our institute was successful in obtaining funding – at least most from BC, and Our institute was successful in obtaining funding – at least most from BC, and not only from Czech sources, but also from highly competitive international sources, such as f. e. Astrid Holzer – HORIZON 2020 (Para. Fish. Control) Jula Lukeš et al. – GAČR grant Tomáš Scholz et al. – GAČR grant Martin Kváč et al. – GAČR grant Libor Grubhoffer + Petr Kopáček et al. – EU - Antidote Miroslav Oborník et al. – GAČR grant Zdeněk Paris – GAČR grant (post-doc) Veronika Urbanová – GAČR grant (post-doc) Astrid Holzer – contract from Norvegian fisheries Jana Nebesářová – Czech-Bio. Imaging

2015 – 7 GAČRů!! ( z celkových 11 na BC) 2014 – 3 GAČRy 2015 – 7 GAČRů!! ( z celkových 11 na BC) 2014 – 3 GAČRy 2013 – 4 GAČRy 2012 – 11 GAČRů 2011 – 6 GAČRů ROZPOČET ÚSTAVU 2014 Celkem 118 mil, z toho režie 47 mil (40%), 37% mezd placeno z režie, 63% mezd z grantů (proto tolik odměn – možná až moc, viz další slide!) 2013 Celkem 121 mil, z toho režie 47 mil (39%) 2012 Celkem 114 mil, z toho režie 46 mil (40%) 2011 Celkem 97 mil, z toho režie 53 mil (55%)

VĚDECKÁ PRODUKCE - SROVNÁNÍ = ŠPATNÝ ROK (BAD YEAR)!!! 2014 2013 2012 4 8 VĚDECKÁ PRODUKCE - SROVNÁNÍ = ŠPATNÝ ROK (BAD YEAR)!!! 2014 2013 2012 4 8 8 116 117 120 Chapters 4 6 3 Monographs 1 5 0 327, 48 408, 38 399, 48 Papers with IF > 8 Papers with IF Suma IF We cannot afford another one like this…

2014 Relative papers with IF* Relative IF* Papers with IF# Lukeš lab 13, 8 2014 Relative papers with IF* Relative IF* Papers with IF# Lukeš lab 13, 8 39, 9 19 55, 35 Oborník lab 2, 0 4, 9 6 11, 32 Zíková lab 0, 0 0 0 Paris lab 0, 0 0 0 Horák lab 0, 0 0 0 Grubhoffer/Rudenko lab 12, 8 51, 0 17 64, 51 Kopáček lab 1, 3 5, 0 5 17, 95 Růžek lab 10, 4 46, 7 14 57, 45 Kotsyfakis lab 6, 3 29, 3 7 31, 85 Hajdušek lab 1, 2 4, 1 4 13, 46 Holzer lab 8, 8 19, 6 11 25, 26 Kváč lab 13, 0 38, 2 16 45, 22 Scholz lab 36, 0 58, 6 38 63, 97 Štefka lab 4, 5 15, 8 5 17, 53 Pomajbíková lab 1, 5 4, 4 6 18, 27 Nebesářová lab 2, 9 7, 6 6 16, 91 * Relativized according to number of authors from individual labs; # I find the right-most number somewhat more important, because we don´t want to punish collaboration (too much)

Relative IF No. 2014 Researchers (2. 1. 2015) + Posdocs* 2013 (27. 11. 2013) Relative IF No. 2014 Researchers (2. 1. 2015) + Posdocs* 2013 (27. 11. 2013) 2012 (7. 1. 2013) Lukeš lab 9 39, 9 97, 9 112, 7 Oborník lab 6 4, 9 15, 7 42, 9 Zíková lab 3 0, 0 3, 3 Paris lab 1 0, 0 - - Horák lab 1 0, 0 10, 1 - Grubhoffer/Rudenko lab 5 51, 0 24, 7 4, 5 Kopáček lab 4 5, 0 6, 7 4, 7 Růžek lab 3 46, 7 21, 5 12, 4 Kotsyfakis lab 1 29, 3 47, 0 Hajdušek lab 2 4, 1 0, 0 - Holzer lab 7 19, 6 22, 2 28, 0 Kváč lab 3 38, 2 45, 6 27, 5 Scholz lab 8 58, 6 70, 8 76, 6 Štefka lab 4 15, 8 48, 7 5, 2 Pomajbíková lab 1 4, 4 1, 84 - Nebesářová lab 3 7, 6 18, 0 22, 8 Relativized according to number of authors from individual labs; *2014

No. Researchers + Posdocs* 2014 (2. 1. 2015) 2013 (2. 1. 2014) 2012 (2. No. Researchers + Posdocs* 2014 (2. 1. 2015) 2013 (2. 1. 2014) 2012 (2. 8. 2013) Lukeš lab 9 2 (1) 15 (3) 14 (7) Oborník lab 6 0 4 (2) 6 (3) Zíková lab 3 0 0 0 Paris lab 1 0 - - Horák lab 1 0 2 (1) - Grubhoffer/Rudenko lab 5 2 (1) 1 Kopáček lab 4 1 1 1 Růžek lab 3 1 (1) 2 1 Kotsyfakis lab 1 4 (1) 6 Hajdušek lab 2 0 0 - Holzer lab 7 2 1 2 (1) Kváč lab 3 3 1 0 Scholz lab 8 2 2 1 Štefka lab 4 1 2 (1) 0 Pomajbíková lab 1 1 0 - Nebesářová lab 3 0 0 3 Papers with IF > 4 (IF > 8) *2014

Papers with IF > 8 Editorial Material: Cabezas-Cruz A. , Valdés J. J. , Papers with IF > 8 Editorial Material: Cabezas-Cruz A. , Valdés J. J. , de la Fuente J. 2014: Cancer research meets tick vectors for infectious diseases. Lancet Infectious Diseases 14: 916– 917. IF = 19, 446 Porcel B. M. , Denoeud F. , Opperdoes F. , Noel B. , Madoui M. -A. , Hammarton T. C. , Field M. C. , Da Silva C. , Couloux A. , Poulain J. , Katinka M. , Jabbari K. , Aury J. -M. , Campbell D. A. , Cintron R. , Dickens N. J. , Docampo R. , Sturm N. R. , Koumandou V. L. , Fabre S. , Flegontov P. , Lukeš J. , Michaeli S. , Mottram J. C. , Szoor B. , Zilberstein D. , Bringaud F. , Wincker P. , Dollet M. 2014: The streamlined genome of Phytomonas spp. relative to human pathogenic kinetoplastids reveals a parasite tailored for plants. PLOS Genetics 10: e 1004007. IF = 8, 167 Schnettler E. , Tykalová H. , Watson M. , Sharma M. , Sterken M. G. , Obbard D. J. , Lewis S. H. , Mc. Farlane M. , Bell-Sakyi L. , Barry G. , Weisheit S. , Best S. M. , Kuhn R. J. , Pijlman G. P. , Chase-Topping M. E. , Gould E. A. , Grubhoffer L. , Fazakerley J. K. , Kohl A. 2014: Induction and suppression of tick cell antiviral RNAi responses by tick-borne flaviviruses. Nucleic Acids Research 42: 14. IF = 8, 808 Waisberg M. , Molina-Cruz A. , Mizurini D. M. , Gera N. , Sousa B. C. , Ma D. , Leal A. C. , Gomes T. , Kotsyfakis M. , Ribeiro J. M. , Lukszo J. , Reiter K. , Porcella S. F. , Oliveira C. J. , Monteiro R. Q. , Barillas-Mury C. , Pierce S. K. , Francischetti I. M. 2014: Plasmodium falciparum Infection Induces Expression of a Mosquito Salivary Protein (Agaphelin) That Targets Neutrophil Function and Inhibits Thrombosis without Impairing Hemostasis. PLo. S Pathogens 10: e 1004338. IF = 8, 057

Papers with IF > 8 = but 2013! Flegontov P. , Votýpka J. , Papers with IF > 8 = but 2013! Flegontov P. , Votýpka J. , Skalický T. , Logacheva M. D. , Penin A. A. , Tanifuji G. , Onodera N. T. , Kondrashov A. S. , Volf P. , Archibald J. M. , Lukeš J. 2013: Paratrypanosoma Is a Novel Early-Branching Trypanosomatid. CURRENT BIOLOGY 23: 1787– 1793. IF = 9, 494. Husník F. , Nikoh N. , Koga R. , Ross L. , Duncan R. P. , Fujie M. , Tanaka M. , Satoh N. , Bachtrog D. , Wilson A. C. , von Dohlen C. D. , Fukatsu T. , Mc. Cutcheon J. P. 2013: Horizontal gene transfer from diverse bacteria to an insect genome enables a tripartite nested mealybug symbiosis. CELL 153(7): 1567– 1578. IF = 31, 957 Janouškovec J. , Horák A. , Barott K. L. , Rohwer F. L. , Keeling P. J. 2013: Environmental distribution of coralassociated relatives of apicomplexan parasites. ISME JOURNAL 7: 444– 447. IF = 8, 951 Janouškovec J. , Sobotka R. , Lai D. -H. , Flegontov P. , Koník P. , Komenda J. , Ali S. , Prášil O. , Pain A. , Oborník M. , Lukeš J. , Keeling P. J. 2013: Split photosystem protein, linear-mapping topology and growth of structural complexity in the plastid genome of Chromera velia. MOLECULAR BIOLOGY AND EVOLUTION 30: 2447– 2462. IF = 10, 353 Kořený L. , Oborník M. , Lukeš J. 2013: Make it, take it or leave it: Heme metabolism of parasites. PLOS PATHOGENS 9: e 1003088. IF = 8, 136 Ma D. , Mizurini D. M. , Assumpçăo T. C. F. , Li Y. , Qi Y. , Kotsyfakis M. , Ribeiro J. M. C. , Monteiro R. Q. , Francischetti I. M. B. 2013: Desmolaris, a novel Factor XIa anticoagulant from the salivary gland of the vampire bat (Desmodus rotundus) inhibits inflammation and thrombosis. BLOOD 122: 4094– 4106. IF = 9, 060 Preston S. G. , Majtán J. , Kouremenou C. , Rysnik O. , Burger L. F. , Cabezas-Cruz A. , Guzman M. C. , Nunn M. A. , Paesen G. C. , Nuttall P A. , Austyn J. M. 2013. Novel immunomodulators from hard ticks selectively reprogramme human dendritic cell responses. PLOS PATHOGENS 9(6): e 1003450. IF = 8, 136 Ward J. D. , Bojanala N. , Bernal T. , Ashrafi K. , Asahina M. , Yamamoto K. R. 2013: Sumoylated NHR-25/NR 5 A regulates cell fate during C. elegans vulval development. PLOS GENETICS 9: e 1003992. IF = 8, 517

Slide from last year – apparently did not stimulate much… General comparison of Czech Slide from last year – apparently did not stimulate much… General comparison of Czech research with Western Europe and USA – still not good enough… We need to double our production in order to close the gap with the best EU countries, not necessarily more papers, but higher impact and more respected = cited papers On top of that – CAS/AVCR has to produce at least double than the best Czech We want Western standards from So. S, grant agencies, suppliers etc. , but first of all, we shall deliver according to them…

 good stuff Some additional • Prémie Otto Wichterleho – Jan Štefka • Post-doc good stuff Some additional • Prémie Otto Wichterleho – Jan Štefka • Post-doc z centrálních zdrojů AV – Zoltan Fussy dostal, Jana Veselá to bohužel nedostala • 4. ročník soutěže Jihočeská ratolest – M+M Jirků • A lot of popularization of the institute • Thanks to mostly Brian P. , we have a complete list of equipment

Science citation index (without primary autocitation) Some additional good stuff Citations are increasing, especially Science citation index (without primary autocitation) Some additional good stuff Citations are increasing, especially important to see it happening with the young guys – if we want to be eligible for big EU funding, this is a must… name / year Miroslav Oborník Julius Lukeš František Moravec Tomáš Scholz David Modrý Aleš Horák Jan Votýpka Milan Jirků Michalis Kotsyfakis Libor Grubhoffer Radek Šíma Petr Kopáček Martin Kváč Václav Hypša Nataliia Rudenko Jan Kopecký Alena Panicucci Zíková Bohumil Sak Maryna Golovchenko Jiří Vávra Ivan Fiala Aneta Kostadinova Marie Vancová Daniel Růžek Daniel Sojka Jana Nebesářová Jindřich Chmelař Miloslav Jirků Luděk Kořený Jiří Salát Anna Faltýnková Klára J. Petrželková Ondřej Hajdušek Roman Kuchta Silvie Trantírková (Foldýnová) Martin Kostka Ph. D 1995 1991 1970 1989 2000 2007 2004 1987 2010 1993 2003 1994 2002 1983 2006 1960 2006 1994 2006 2008 2007 1990 2010 2008 2011 2003 2006 2003 2009 2007 2006 2008 2011 310 340 147 215 123 95 111 86 49 83 63 83 46 71 56 55 90 39 51 55 63 54 32 45 72 9 20 18 22 30 60 18 14 2012 325 351 226 293 181 150 134 103 41 89 92 82 55 88 52 70 110 50 44 69 69 56 56 57 52 83 24 35 28 32 35 73 35 16 2013 402 310 250 179 169 140 126 125 119 118 116 110 98 94 90 90 90 80 79 73 72 71 67 65 64 61 55 45 43 42 42 41 39 39 38

SOCIAL FUND (použití prostředků) • Příspěvek na stravování (úvazek 3/8) • Půjčky na pořízení SOCIAL FUND (použití prostředků) • Příspěvek na stravování (úvazek 3/8) • Půjčky na pořízení bytu a jeho vybavení – zastaveno! • Finanční pomoc v mimořádných situacích • Významná životní výročí • Kurzy angličtiny (4 × 60 minut/týdně) • Vánoční večírek – 45 tis.

 What expects us in 2015… • Big evaluation of the institute • Animal What expects us in 2015… • Big evaluation of the institute • Animal house construction shall finish in September • Discussion on who will move there • Insulation of the building project • Lower total budget (big projects such as Praemium, Modbiolin and Bioglobe will terminate) • 10 US students in summer • Better scientific production – needed!!!