Транспортные системы • • Транспортеры Механорецепторы Терморецепторы Аквапорины Порины Экспортные каналы Токсины Gap junction
Транспортеры
Model of peptide transport in epithelial cells from intestine and kidney
Peptide transporter Membrane domains in green – substrate-binding part; colored residues are critical to function
Phylogenetic tree for members of the PTR family
Neurotransmitter transporter families
GABA transport
Leu transporter from Aquifex aeolicus
Leu transporter from Aquifex aeolicus
Lactose transporter E. Coli
Lactose transporter E. Coli. Residues involved in substrate or H+ interaction
Na+-coupled Glu transporter from Pyrococcus horikoshii (Glt. Ph)
Glu transporter from Pytococcus horikoshii
Lactose transporter from E. coli
Механорецепторы
Mechanosensitive and voltage activated channel from E. Coli of small conductance ~ 1 n. S (Msc. S). TM 3 helices lining pore, TM 1 and TM 2 are candidates for the tension and voltage sensor.
Терморецепторы
корица андрографолид камфора
Test receptors
Аквапорины
Порины
Omp 32
Maltoporin from Salmonella typhimurium
Экспортные каналы
Model of Acr. B-Acr. A-Tol. C complex in E. coli
Structure of Acr. B from E. coli at 3. 5 A resolution
Trimeric Acr. B pump from E-coli with large central cavity of 5000 cubic angstroms
To. IC & OM proteins
To. IC
ATP dependent drug efflux system
Msb. A (E. coli)
ABC transporter proteins
ATP-induced conformational changes Mod. BC-A Sav 1866
Токсины
a-Hemolysin (Staphylococcus aureus) Mr 33, 2 k. Da 16 b-strands heptamer
Yersinia protein injectisome
Modeles of type III (T 3 SS) and type IV (T 4 SS) secretion systems
Gap junction