THERE IS A NEW AIR ABOUT INDIA ISLANDS

“THERE IS A NEW AIR ABOUT INDIA” ISLANDS OF EXCELLENCE IN : EDUCATION • HEALTHCARE • INDUSTRY AGRICULTURE RESEARCH

ENGLISH`S NEW SUPERPOWER Ø WITH AN ENGLISH-SPEAKING POPULATION NOW LIKELY TO HAVE SURPASSED THAT OF BRITAIN AND THE US, INDIA IS SET TO BECOME A LINGUISTIC SUPER POWER. Ø INDIA CURRENTLY HAS A SPECIAL PLACE IN THE ENGLISH LANGUAGE RECORD BOOKS – AS THE COUNTRY WITH THE LARGEST ENGLISH SPEAKING POPULATION IN THE WORLD. TEN YEARS AGO THAT RECORD WAS HELD BY THE US. NOT ANY MORE !

INDIA ON TOP Ø AMONG THE FASTEST GROWING ECONOMIES “FOURTH LARGEST ECONOMY”: WASHINGTON POST Ø AMONG THE TOP FOUR FDI DESTINATIONS MORE FII INTO INDIAN EQUITIES THAN CHINA, KOREA & TAIWAN COMBINED “ POTENTIALLY BIGGER LONG-TERM GROWTH STORY THAN CHINA ”: GOLDMAN SACHS

INDIA ON TOP ECONOMIST INTELLIGENCE UNIT (SEPT 04) CENTERS OF OVERSEAS INVESTMENT : % COUNTRY 39 29 CHINA USA 28 INDIA “ INDIA AN R & D SPOT “

INDIA ON TOP LARGEST MILKY WAY ! 90 MILLION TONS IN 2004 Ø 20 MILLION TONS MORE THAN USA, THE SECOND BIG PRODUCER Ø

INDIA ON TOP NO. 1 IN MANY AREAS ! Ø Ø SUGAR PRODUCTION BANANA, PAPAYA, MANGO EGG PLANT, CAULIFLOWER, PEAS SPICES, COCONUT, ARECNUT

INDIA ON TOP Ø Ø INDIAN BRANDY, BUT GLOBAL KICK Mc. Dowell's NO. 1 WORLD`S TOP SELLING BRAND, DISPLACES E & J

INDIAN MULTINATIONALS DESI COMPANIES GOBBLING UP FOREIGN ENTITIES ! Ø Ø IN 2003, 40 COMPANIES TAKEN OVER TATA TEA : TETLEY TEA TATA : DAEWOO ESSEL PACKAGING : PROPAK (SWISS) BIGGEST CARBON BLACK : KUMARAMANGALAM BIRLA

INDIA AN R & D POWERHOUSE ENGLISH SPEAKING KNOWLEDGE WORKERS Ø 30%-50% COST SAVING : SWATI PIRAMAL Ø 1/5 TH -1/7 TH COST IN EUROPE : RANBAXY Ø BANGALORE : FASTEST GROWING BIOCLUSTER IN ASIA Ø

THE BIOTECH INDUSTRY Ø Ø Ø Ø MORE NEW DRUG APPROVALS FROM FDA BY BT COMPANIES THAN PHARMA IN 2004 USA: THE BIRTHPLACE OF MODERN BT TOWER OVER THE FIELD ! 4400 BT FIRMS WORLDWIDE 2200 US FIRMS PUBLICLY TRADED 2004 REVENUES $43 BILLION AMERICAN INDUSTRY RAISED $17 BILLION FROM PUBLIC & PRIVATE FUNDS IN 2004 (5 TIMES THAT OF EUROPE !) GERMAN BT FLOUNDERED BRITISH BT BRUISED & BLOODIED BUT UNBOWED (ERNST & YOUNG)

ASIAN BIOTECH Ø DOMINATED BY AUSTRALIA : $2 BN, i. e. 75 % OF ASIAN REVENUE Ø INTERESTING COMPANIES SPRINGING UP IN INDIA, CHINA, SINGAPORE

SINGAPORE BIOPOLIS Ø TO HOST 2000 SCIENTISTS FROM AROUND THE WORLD INCLUDING ALLEN COLEMAN OF DOLLY FAME Ø R & D BUDGET OF $ 7 BILLION OVER 5 YEARS Ø 500 STUDENTS SENT ABROAD FOR Ph. D

INDIAN BIOTECH SECTOR Ø Ø Ø ABLE (ASSOC. BIOTECH LED ENTERPRISES) REVENUE - $ 1 BILLION FIVE FOLD INCREASE ($ 5 BILLION) BY 2010 EMPLOYED 9000 S & T PERSONNEL IN 2004 40% INCREASE IN 2005

PHARMA EXPORTS TO GROW TO $6 bn INDIA IS ONE OF THE TOP FIVE MANUFACTURERS OF BULK DRUGS IN THE WORLD ! Ø PHARMA EXPORTS $6 bn BY 2015 FROM THE CURRENT LEVEL OF LESS THAN $2 bn Ø THE R & D ACTIVITIES ARE TARGETED BOTH AT NEW DRUG DISCOVERY RESEARCH AND NOVEL DRUG DELIVERY SYSTEMS (NDDS). THE MAJOR COMPANIES INVESTED OVER Rs. 1000 CRORES LAST YEAR.

INDIAN BIOTECH SECTOR SERUM INSTITUTE THE VACCCINE GIANT ! Ø Ø Ø LARGEST INDIAN BT COMPANY LARGEST VACCINE PRODUCER IN THE WORLD PRODUCES 675 m DOSAGES PER DAY DISTRIBUTED AND USED IN 137 COUNTRIES OF THE WORLD (W. H. O) 30% OF WORLD`S CHILDREN PROTECTED BY SERUM INTITUTE`S VACCINE

INDIAN BIOTECH SECTOR INDIAN VACCINE IMPACT Ø Ø Ø Ø HAFFKINE INSTITUTE , MUMBAI PIONEER IN POLIO VACCINE PRODUCTION IMMUNISED 150 m CHILDREN ERADICATED POLIO HEPATITIS B VACCINES SHANTA BIOTECH BHARAT BIOTECH WOCKARDT, REDDY`S

INDIAN BIOTECH SECTOR NEUTRACEUTICALS PARRY NEUTRACEUTICALS SPIRULINA, DUNALIELLA -CAROTENE, ASTAXANTHIN Ø THAPAR Ø ABL BIOTECHNOLOGIES Ø SAMY CHEMICALS Ø

INDIAN BIOTECH SECTOR Ø Ø EMERGING INTERNATIONAL HUB FOR CONTRACT RESEARCH MANY START-UP COMPANIES IN THE LAST FOUR YEARS BPO RPO CRAM RESEARCH & MANUFACTURING BIOCON (BANGALORE) SERUM INSTITUTE (PUNE), PANACEA BIOTECH (DELHI), NICHOLAS PIRAMAL (MUMBAI), NOVO NORDSIK (BANGALORE)

APOLLO HOSPITAL ENTERPRISES Ø Ø Ø Ø CHENNAI, DELHI, HYDERABAD Rs 150 CRORE REVENUE IN 2004 -2005 40% REVENUE FROM CARDIAC CARE 39% REVENUE FROM PHARMA BUSINESS TO SET UP SEVEN 120 BED HOSPITALS IN MINIMETROS MOU WITH JOHNS HOPKINS MEDICINE INTERNATIONAL TO SET UP CENTRAL REFERENCE LABS IN CHENNAI, HYDERABAD AND DELHI - HIGH END CLINICAL TESTING TO SET UP INSTITUTE OF MINIMAL INVASIVE SURGERY

COLLABORATIVE R & D Ø Ø Ø RANBAXY : MEDICINES FOR MALARIA VENTURE (MMV) GENEVA ANTIMALARIAL MOLECULE - Rbx 11160 RANBAXY : GLAXO SMITH KLINE Dr. REDDY`S, ZYDUS CADILA, NICHOLAS PIRAMAL (EMERGING ACTIVITIES)

BIOCON TIES WITH NOBEX TO DEVELOP ORAL INSULIN Ø BIOCON HAS ENTERED INTO A RESEARCH COLLABORATION WITH NORTH CAROLINA`S NOBEX CORPORATION TO JOINTLY DEVELOP ORAL INSLIN FOR THE GLOBAL AND INDIAN MARKET

ORCHID CHEM`S IPR FILE COUNT TOUCHES 200 FILINGS FOR NEW DRUGS, DISCOVERY SYSTEMS AT 25% OF TOTAL FIIS TO HIKE STAKE IN ORCHID CHEMICALS ORCHID JOINS PAR PHARMA TO MARKET GENERICS IN US ORCHID WANTS TO CRACK ORAL CEPHALOSPORIN FORMULATIONS MARKET ORCHID FILES ANDA FOR CEFAZOLIN

ORCHID CHEMICALS & PHARMACEUTICALS LTD. Ø Ø Ø Ø 300 SCIENTIFIC PERSONNEL 400 BY 2006 Rs. 150 CRORES IN R & D DURING LAST 7 YEARS FDA/GLP ANIMAL FACILITY, LABS ANTI-INFLAMATORY, OBESITY, CANCER, HERBAL MEDICINE TARGET : $1 bn BY 2010 JV IN USA, ITALY , CHINA

PEP PILL: GLOBAL BIZ FORM 60% OF SALES NOW WOCKHARDT EYES ANOTHER EUROPEAN TAKEOVER Ø AFTER ACQUIRING THREE EUROPEAN COMPANIES IN THE PAST, IT IS LOOKING TO ACQUIRE ONE MORE EUROPEAN COMPANY Ø WOCKHARDT BUYS GERMAN FIRM * DRL ACQUIRES TRIGENESIS OF US Ø TORRENT PHARMA TO ACQUIRE GERMAN CO FOR Rs 300 CRORE Ø JUBILANT ORGANOSYS ACQUIRES TWO BELGIAN PHARMA FIRMS Ø Rs 75 CRORE DEAL TO STRENGTHEN PRESENCE IN EU, ITS MAIN EXPORT MARKET Ø WYETH SELLS BULK DRUGS PLANT TO RUNWAL GROUP FOR Rs 60 CRORE Ø

NICHOLAS PIRAMAL PLANS BIG DIAGNOSTICS PUSH HAS SIGNED ALLIANCES WITH DIASYS GMBH, A GERMAN FIRM, HYPOGUARD, A UK-BASED COMPANY PART OF THE MEDISYS GROUP, AND CHOLESTECH, A US-BASED COMPANY.

STRAND IN DEAL WITH US CO FOR MICROARRAY PLATFORM Ø HAS ENTERED INTO AN AGREEMENT WITH US MAJOR AFFYMETRIX, FOR PROVIDING MICROARRAY PLATFORM Ø MICROARRAYS ARE POWERFUL TOOLS THAT ALLOW SCIENTISTS TO MEASURE AND COMPARE THE EXPRESSION LEVELS OF THOUSANDS OF GENES IN A SINGLE EXPERIMENT.

SHASUN HIKES CONTRACT THRUST Ø USFDA-COMPLIANT R&D (RESEARCH AND DEVELOPMENT) CENTRE NEAR CHENNAI AT AN INVESTMENT OF ABOUT RS. 35 CRORE. Ø THE NEW FACILITY WOULD HOUSE ABOUT EIGHT LABORATORIES AND NEARLY 300 SCIENTISTS.

Ø MALLADI DRUGS ACQUIRES U. S. FIRM Ø SUN PHARMA’S PLANS FOR US BUY GET A BOOST Ø ZYDUS CADILA UPPING PRESENCE ABROAD

CLINICAL RESEARCH Ø Ø Ø $ 1 BILLION BY 2008 BIOCON – CLINIGENE RELIANCE CLINICAL RESEARCH SERVICES

QUINTILES : WORLD`S LARGEST CLINICAL RESEARCH OUTFIT Ø Ø Ø IN INDIA SINCE 1997 MUMBAI, AHMEDABAD, BANGALORE 900 PEOPLE 2000 PEOPLE BY 2008

MERCK & CO $40 bn US GIANT Ø WITH APOTHECARIES LTD (DELHI, CRO) Ø CLINICAL TRIALS ACROSS 20 CENTERS IN INDIA FOR ANTIBIOTIC , CANCER

SRL-RANBAXY IN TIE-UP WITH UK HOSPITALS GROUP Ø PATHOLOGY TESTING IN INDIA Ø NINE LABS IN INDIA, MAIN LAB IN MUMBAI

CCMB SPOTS GENETIC JACKPOT IN INDIA Ø WITH ITS 4, 635 ANTHROPOLOGICALLY WELL-DEFINED ENDOGAMOUS POPULATIONS – OF WHICH 532 ARE TRIBES, INCLUDING 72 PRIMITIVE POPULATIONS, INDIA IS A BIGGER LABORATORY THAN ICELAND TO STUDY POPULATION/COMMUNITY-BASED GENETIC DISEASES. Ø BIOCON CHAIRMAN KIRAN MAZUMDAR-SHAW ARGUES THAT THE COUNTRY’S UNIQUE GENE POOLS ARE “GOLD MINES”. Ø ABOUT 50 MILLION INDIVIDUALS ARE AFFECTED WITH GENETIC DISEASES IN INDIA.

GSK BIO TARGETS INDIA FOR R & D Ø GLAXO SMITH KLINE BIOLOGICALS, THE VACCINE BUSINESS OF GLAXO SMITH KLINE (GSK), WILL MAKE INDIA A GLOBAL HUB FOR CLINICAL RESEARCH AND DEVELOPMENT Ø HI-TECH VACCINES FOR AIDS, DENGUE, MALARIA AND TB Ø THE TB VACCINE TO START PHASE II TRIALS IN INDIA

Ø PEP PILL: SANDOZ INVESTS $13 M IN THIRD FACILITY IN INDIA. Ø ROCHE DIAGNOSTICS EYES INDIA FOR PRODUCTION, R&D.

GE HEALTHCARE SOME OF US GROW UP TO BE ENGINEERS OR DOCTORS SOME OF US GROW UP TO BE BOTH ! Ø Ø Ø MEDICAL IMAGING AND INFORMATION TECHNOLOGIES MEDICAL DIAGNOSTICS PATIENT MONITORING SYSTEMS, DISEASE RESEARCH, DRUG DISCOVERY AND BIOPHARMACEUTICALS EARLY DETECTION OF DISEASE AND TREATMENT OF CONDITIONS LIKE CANCER, ALZHEIMER`S AND CARDIOVASCULAR DISEASES GTO INDIA HAS OVER 90 PATENTS TO ITS CREDIT AND OVER 100 INVENTION DISCLOSURES IN THE YEAR 2003 ALONE.

GENETICS SPECIALTIES LAUNCHED Ø CANCER GENETICS, A BIOTECHNOLOGY COMPANY BASED IN THE US, HAS ANNOUNCED THE LAUNCH OF GENETICS SPECIALTIES IN BANGALORE. Ø GENETIC DIAGNOSTIC TOOL FOR INDIAN HEALTH MARKET

GM RESEARCH THRIVING IN INDIAN ACADEMIA WHEAT, RICE, SUGARCANE, TOBACCO BANANA, VEGIES, POTATO, OIL SEEDS $15 MILLION/YEAR GOVT. LABS Vs $ 10 MILLION/ YEAR BY SEED COST, 20 GOVT. INSTITUTES ON 16 CROPS SEVERAL PRIVATE COMPANIES ON 10 CROPS IARI, JNU, NCPGR, U. DELHI, MKU, SRI (CBE), NBRI, TNAU, ICRISAT.

ICRISAT, HYDERABAD Ø WORLD`S FIRST TRANSGENIC GROUNDNUT: RESISTANCE TO INDIAN PEANUT CLAMP VIRUS ; ROSETTE DISEASE IN AFRICA Ø TRANSGENIC BT PIGEONPEA, CHICKPEA

GM CROPS RESEARCH IN INDIA Ø Ø Ø RALLIS INDIA (TATAS) RASI, NUSIVEEDU, NAVBHARAT, ANKUR, METAHELIX, AVESTHAGEN INDO-AMERICAN HYBRID SEEDS MONSANTO/MAHICO SYNGENTA (SWISS) BAYER/ PROAGRO(GERMANY)

GM COTTON WILL TREBLE TO 3. 3 m Acres ! (FROM 1. 0 m Acres) Ø Ø Ø INDIA LARGEST COTTON ACREAGE BUT VERY LOW PRODUCTION/ACRE GM SURGE MOSTLY ILLEGAL PLANTING

THE LAS VEGAS PILL Ø Ø PFIZER`S ANGINA DRUG TEST ! MALE VOLUNTEERS NOTED UNUSUAL CONSEQUENCE COMPOUND UK - 92480 BECAME VIAGRA USE OF DOPAMINE AGONISTS : COMPULSIVE GAMBLERS, ALCOHOLICS, GLUTTONS, SEX PESTS

BORED WITH BREAD AND BUTTER BIOTECH ! GO MAKE GREAT WINES ! Ø Ø SIX BANKERS (INCLUDING TWO INDIANS) LEGENDARY MEAL AT CELEBRATED CHEF GORDON RAMSAY`S PETRUS RESTAURANT IN LONDON: SPLASHED £ 44000 CERTIFIED MOST EXPENSIVE MEAL BY GUINESS BOOK OF RECORDS 1947 CHATEAU PETRUS BORDEAUX : £ 12300 (Rs. 10 LAKHS) TWO WINES : £ 11600 AND £ 9400

NICHOLAS PIRAMAL PLANS BIG DIAGNOSTICS PUSH HAS SIGNED ALLIANCES WITH DIASYS GMBH, A GERMAN FIRM, HYPOGUARD, A UK-BASED COMPANY PART OF THE MEDISYS GROUP, AND CHOLESTECH, A US-BASED COMPANY.

INDIA ON TOP RELIANCE INDUSTRIES IS THE WORLD`S : Ø Ø 2 ND LARGEST PRODUCER OF POLYFIBER AND YARN 3 RD LARGEST PRODUCER OF PARAXYLENE 5 TH LARGEST PRODUCER OF PURIFIED TEREPTHALIC ACID (PTA) IT COMBINES THE PEPTIDE PRODUCTION CAPABILITIES OF BIOCON WITH THE PEPTIDE BASED ORAL-DELIVERY TECHNOLOGY OF NOBEX. Ø BIOCON TIES UP WITH VACCINEX FOR ANTIBODIES Ø BIOCON WITH ROCHESTER (NEW YORK) - BASED VACCINEX TO PURSUE DEVELOPMENT OF THERAPEUTIC MONOCLONAL ANTIBODIES (MAbs) TO ADD TO THEIR DISCOVERY PIPELINE. Ø GLOBAL PROJECTED SALES OF MAbs IS EXPECTED TO TOUCH $13 bn BY 2010

THE SCRIPTING OF INDIA NO. 1 THE LIST OF DESI COS POSSESSING WORLD CLASS SIZE AND SCALES GROWING Ø UB GROUP, WHICH WITH THE ACQUITION OF SHAW WALLACE HAS BECOME THE SECOND LARGEST LIQUOR COMPANY IN THE WORLD AFTER DIAGEO Ø HERO HONDA IS SET TO END THE CURRENT FISCAL AS THE LARGEST TWO WHEELER COMPANY IN THE WORLD FOR THE FOURTH YEAR IN SUCCESSION. Ø HERO GROUP COMPANY, HERO CYCLES, IS THE LARGEST COMPANY WITH ANNUAL PRODUCTION OF 5. 4 mn BICYCLES Ø ESSEL PROPACK IS THE WORLD`S LARGEST MANUFACTURER OF LAMINATED TUBES. Ø GLOBAL MARKETSHARE OF MORE THAN 30%, HAS MANUFACTURING FACILITIES IN CHINA, USA, GERMANY, MEXICO, COLUMBIA, VENEZUELA, PHILIPPINES, INDONESIA, EGYPT AND NEPAL. Ø BHARAT FORGE IS THE WORLD`S SECOND LARGEST COMPANY Ø SUNDARAM FASTENERS IS THE WORLD`S THIRD LARGEST BRAKE LINING, FASTENER AND RADIATOR CAPS MANUFACTURERS Ø TATA TEA AND ITS SUBSIDIARY TATA TETLEY TOGETHER CONSTITUTE THE SECOND LARGEST BRANDED PORTFOLIO IN THE WORLD.

STRAND IN DEAL WITH US CO FOR MICROARRAY PLATFORM Ø HAS ENTERED INTO AN AGREEMENT WITH US MAJOR AFFYMETRIX, FOR PROVIDING MICROARRAY PLATFORM ØMICROARRAYS ARE POWERFUL TOOLS THAT ALLOW SCIENTISTS TO MEASURE AND COMPARE THE EXPRESSION LEVELS OF THOUSANDS OF GENES IN A SINGLE EXPERIMENT.

CONTRACT RESEARCH AND AMNUFACTURING(CRAM) Ø Ø Ø Ø Ø TCS INFOSYS WIPRO HCL TECHNOLOGIES ITTIAM SASKEN BIOCON SHASUN DIVI`S

INDIAN MULTINATIONALS MANY INDIAN COMPANIES IN DRAGON COUNTRY ! Ø Ø Ø INFOSYS, TCS, SUNDARAM FASTENERS, BHARAT FORGE RANBAXY NOW SELLS MORE ABROAD THAN IN INDIA HAS SUBSIDIES IN MORE THAN 12 COUNTRIES

SHASUN HIKES CONTRACT THRUST Ø USFDA-COMPLAINT R&D (RESEARCH AND DEVELOPMENT) CENTRE NEAR CHENNAI AT AN INVESTMENT OF ABOUT RS. 35 CRORE. Ø THE NEW FACILITY WOULD HOUSE ABOUT EIGHT LABORATORIES AND NEARLY 300 SCIENTISTS.

CCMB SPOTS GENETIC JACKPOT IN INDIA Ø WITH ITS 4, 635 ANTHROPOLOGICALLY WELL-DEFINED ENDOGAMOUS POPULATIONS-OF WHICH 532 ARE TRIBES, INCLUDING 72 PRIMITIVE POPULATIONS, INDIA IS A BIGGER LABORATORY THAN ICELAND TO STUDY POPULATION/COMMUNITY-BASED GENETIC DISEASES. Ø BIOCON CHAIRMAN KIRAN MAZUMDAR-SHAW ARGUES THAT THE COUNTRY’S UNIQUE GENE POOLS ARE “GOLD MINES”. Ø ABOUT 50 MILLION INDIVIDUALS ARE AFFECTED WITH GENETIC DISEASES IN INDIA.

Ø PEP PILL : SANDOZ INVESTS $13 M IN THIRD FACILITY IN INDIA. Ø ROCHE DIAGNOSTICS EYES INDIA FOR PRODUCTION, R&D.