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Support Unit for Research Evidence (SURE) Mala Mann March 2009 University Health and Medical Support Unit for Research Evidence (SURE) Mala Mann March 2009 University Health and Medical Librarians Group (UHMLG)Spring Forum

Outline SURE Profile Our expertise Our projects Outline SURE Profile Our expertise Our projects

Support Unit for Research Evidence (SURE) ¡ Nationally recognised unit established to support and Support Unit for Research Evidence (SURE) ¡ Nationally recognised unit established to support and produce research to assist evidence based practice and policy ¡ Specialised skills in: Advanced literature searching Critical appraisal Summarising research evidence ¡ Teaching of these skills within the University and in Wales

Evidence-based practice The use of current best evidence in making decisions about the care Evidence-based practice The use of current best evidence in making decisions about the care of individual patients. It involves integrating clinical expertise with the best available clinical evidence from systematic research.

SURE team ¡ Hilary Kitcher ¡ Mala Mann ¡ Fiona Morgan ¡ Helen Morgan SURE team ¡ Hilary Kitcher ¡ Mala Mann ¡ Fiona Morgan ¡ Helen Morgan ¡ Lesley Sander ¡ Rowland Somers ¡ Ruth Turley ¡ Alison Weightman (Director)

Advanced Literature Searching ¡ Building complex search strategies for electronic databases, using: Boolean logic Advanced Literature Searching ¡ Building complex search strategies for electronic databases, using: Boolean logic (combining search terms with OR, AND, or NOT) Wildcards or truncation Limits to refine a search

Social determinants for cancer 1 2 3 4 5 6 7 8 9 10 Social determinants for cancer 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 prosperity. mp. (363) wealth. mp. (4139) unemploy$. mp. (7600) poverty. mp. (21355) earning$. mp. (1971) low pay. mp. (49) salary. mp. (1850) debt$. mp. (1979) arrear$. mp. (16) social class. mp. (23746) socio-economic. mp. (8891) socioeconomic. mp. (83015) social security. mp. (6987) social welfare. mp. (6254) social mobility. mp. (610) housing tenure. mp. (132) home own$. mp. (163) house own$. mp. (13) renter. mp. (7) car own$. mp. (82) overcrowd$. mp. (1251) income. mp. (37143) 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 family conflict. mp. (387) poor housing. mp. (163) educational attainment. mp. (1616) educational achievement. mp. (403) deprivation. mp. (41158) inequalit$. mp. (7500) financial hardship. mp. (104) social position. mp. (359) damp housing. mp. (38) social isolation. mp. (9350) social exclusion. mp. (199) social network$. mp. (2730) decision latitude. mp. (236) social relationship$. mp. (1480) effort-reward. mp. (113) job opportunit$. mp. (174) promotion prospects. mp. (27) social gradient. mp. (135) family breakdown. mp. (46) family conflict. mp. (387) social conflict. mp. (178)

46 47 48 49 50 51 52 53 54 55 56 57 58 59 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 neglect. mp. (7494) social interaction. mp. (2940) vulnerable group$. mp. (759) social adversity. mp. (65) social cohesion. mp. (138 poor environment. mp. (93) social contacts. mp. (673) social attachment$. mp. (97) social integration. mp. (965) emotional ties. mp. (37) perceived inadequacy. mp. (22) civic communit$. mp. (5) domestic violence. mp. (3744) engagement in community. mp. (3) social stigma. mp. (296) social capital. mp. (418) social status. mp. (2220) family status. mp. (271) single parent. mp. (1513) sole parent. mp. (9) lone parent. mp. (35) divorce. mp. (4268) marital separation. mp. (61) ethnic$. mp. (59718) refugee$. mp. (5355) good nutrition. mp. (303) household composition. mp. (164) 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 family composition. mp. (184) crowding. mp. (4126) school performance. mp. (1198) school attendance. mp. (463) housing condition$. mp. (1117) benefit recipient$. mp. (11) household type. mp. (37) housing design. mp. (27) employment status. mp. (1983) economic inactivity. mp. (8) social housing. mp. (91) access to health care. mp. (1878) access to services. mp. (525) community participation. mp. (984) social environment. mp. (26711) Social disadvantage. mp. (237) *"Public Housing"/ (370) property own$. mp. (46) racial$. mp. (12725) sociodemographic. mp. (9350) inequit$. mp. (1698) disadvantaged. mp. (3422) Immigrant$. mp. (7999) Rental. mp. (243) affluen$. mp. (1820) Rented. mp. (166) Salaries. mp. (11250)

100 101 102 103 104 105 106 107 108 109 110 111 112 113 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 Shift work. mp. (1052) Social disparit$. mp. (89) Social effect$. mp. (360) Uninsured. mp. (5085) social inclusion. mp. (76) or/1 -104 (351713) exp Controlled Clinical Trials/ (53225) exp Random Allocation/ (59871) exp Double-Blind Method/ (93163) exp Single-Blind Method/ (11128) ((singl$ or doubl$ or trebl$ or tripl$) adj 5 (blind$ or mask)). ti, ab. (88154) (control$ adj (trial$ or stud$ or evaluation$ or experiment$)). mp. (419822) randomi? ed. hw, ti, ab, pt. (336615) (cohort: or survey: or qualitativ: or cross section: or case stud: or evaluat: or audit: or longitudinal: or questionnaire: ). ti, ab. (1757661) (case stud: or evaluat: or audit: or longitudinal: or questionnaire: ). ti, ab. (1453166) exp Meta-Analysis/ (7588) meta-analys$. ti, ab. or metaanalys$. ab, ti. or meta analys$. ab, ti. (17210) Cochrane. ab, sh, ti. (8158) (review$ or overview$). ti. or review$. pt. or (synthes$ adj 3 (literature$ or research or studies or data)). ab, ti. (1361158) pooled analys$. ab, ti. or ((data adj 2 pool$) and studies). mp. (3068) 120 ((hand or manual or database$ or computer$) adj 2 search$). ab, ti. (10520) 121 ((electronic or bibliographic$) adj 2 (database$ or data base$)). ab, ti. (2627) 122 ((review$ or overview$) adj 10 (systematic$ or methodologic$ or quantitativ$ or research$ or literature$ or studies or trial$ or effective$)). ab. (148334) 123 census$. mp. (10083) 124 registry. mp. (22497) 125 registries. mp. (30974) 126 follow up stud$. mp. (356983) 127 or/106 -126 (3598245) 128 neoplasm$. mp. (1486462) 129 malignan$. mp. (273106) 130 Polycythemia Vera. mp. (3927) 131 Myeloproliferative Disorder$. mp. (4717) 132 cancer$. mp. (611077) 133 exp neoplasms/ (1830218) 134 tumo? r$. mp. (951252) 135 Myelodysplastic Syndrome$. mp. (9373) 136 Immunoproliferative Disorder$. mp. (133) 137 or/128 -136 (2145924) 138 105 and 127 and 137 (13438)

¡ 139 138 not (Algeria$ or Egypt$ or Liby$ or Morocc$ or Tunisia$ or ¡ 139 138 not (Algeria$ or Egypt$ or Liby$ or Morocc$ or Tunisia$ or Western Sahara$ or Angola$ or Benin or Botswana$ or Burkina Faso or Burundi or Cameroon or Cape Verde or Central African Republic or Chad or Comoros or Congo or Djibouti or Eritrea or Ethiopia$ or Gabon or Gambia$ or Ghana or Guinea or Keny$ or Lesotho or Liberia or Madagasca$ or Malawi or Mali or Mauritania or Mauritius or Mayotte or Mozambiq$ or Namibia$ or Nigeria$ or Reunion or Rwand$ or Saint Helena or Senegal or Seychelles or Sierra Leone or Somalia or South Africa$ or Sudan or Swaziland or Tanzania or Togo or Ugand$ or Zambia$ or Zimbabw$ or China or Chinese or Hong Kong or Macao or Mongolia$ or Taiwan$ or Belarus or Moldov$ or Russia$ or Ukraine or Afghanistan or Armenia$ or Azerbaijan or Bahrain or Cyprus or Cypriot or Georgia$ or Iran$ or Iraq$ or Israel$ or Jordan$ or Kazakhstan or Kuwait or Kyrgyzstan or Leban$ or Oman or Pakistan$ or Palestin$ or Qatar or Saudi Arabia or Syria$ or Tajikistan or Turkmenistan or United Arab Emirates or Uzbekistan or Yemen or Bangladesh$ or Bhutan or British Indian Ocean Territory or Brunei Darussalam or Cambodia$ or Indonesia$ or Lao or People's Democratic Republic or Malaysia$ or Maldives or Myanmar or Nepal or Philippin$ or Singapore or Sri Lanka or Thai$ or Timor Leste or Vietnam or Albania$ or Andorra or Bosnia$ or Herzegovina$ or Bulgaria$ or Croatia$ or Estonia or Faroe Islands or Greenland or Liechtenstein or Lithuani$ or Macedonia or Malta or maltese or Romania or Serbia$ or Montenegro or Slovenia or Svalbard or Argentina$ or Belize or Bolivia$ or Brazil$ or chile or Chilean or Colombia$ or Costa Rica$ or Cuba or Ecuador or El Salvador or French Guiana or Guatemala$ or Guyana or Haiti or Honduras or Jamaica$ or Nicaragua$ or Panama or Paraguay or Peru or Puerto Rico or Suriname or Uruguay or Venezuela or developing countr$ or south America$). ti, sh. (11890) ¡ 140 limit 139 to (humans and English language and yr="2001 - 2006") (5315)

Critical Appraisal The process of systematically examining research evidence to assess its validity, results Critical Appraisal The process of systematically examining research evidence to assess its validity, results and relevance before using it to inform a decision “The medical literature can be compared to a jungle. It is fast growing, full of dead wood, sprinkled with hidden treasure and infested with spiders and snakes. ” Peter Morgan, Scientific Editor, Canadian Medical Association

Summarising the Evidence Making a summary of the research papers appraised; Summarising the methodology Summarising the Evidence Making a summary of the research papers appraised; Summarising the methodology and quality of the individual studies and pooling the results.

Learning, Teaching & Research Support Evidence based information literacy skills: ¡ Teaching database searching Learning, Teaching & Research Support Evidence based information literacy skills: ¡ Teaching database searching ¡ Critical appraisal training ¡ Supporting systematic reviews and other research projects ¡ Supporting researchers with grant applications

Completed Projects Centre for Health and Environmental Research ¡ Information support for NICE guidance Completed Projects Centre for Health and Environmental Research ¡ Information support for NICE guidance including: • • • Population health effects associated with chronic low level exposure to environmental toxicants (2004) National Institute for Health and Clinical Excellence (NICE) ¡ ¡ Obesity: the prevention, identification, assessment and management of overweight and obesity in adults and children (2006) http: //www. nice. org. uk/CG 043 Systematic and other reviews: terms and definions used by UK organisations and selected databases. Systematic review and Delphi survey (2006) http: //www. nice. org. uk/nice. Media/docs/systematic% 20 reviews%20 v 5%20 FINAL. pdf Welsh Assembly Government ¡ Identification of determinants of health indicators for cancer, child health and older people’s health(2008) Workplace & physical activity Health inequalities Mental health and the workplace Children and physical activity Needle exchange. Identification of determinants of health indicators for cancer, child health and older people’s health (2007) Clinical Engineering Device Assessment and Reporting (CEDAR) ¡ Techniques for the treatment of varicose veins (2008) Wales Centre for Health ¡ How effective are Health Impact Assessment and Participatory Action Research as tools for public engagement? (2008)

Guidelines to inform Government recommendations Guidelines to inform Government recommendations

http: //new. wales. gov. uk/topics/health/ocmo/research/gain/socialdeterminants/? lang=en http: //new. wales. gov. uk/topics/health/ocmo/research/gain/socialdeterminants/? lang=en

National Library for Health Oral Health Specialist Library • Repository of oral health research National Library for Health Oral Health Specialist Library • Repository of oral health research – methodically identified – critically appraised – summarised • Rapid access to published evidence – best available – quality checked

Systematic Reviews of Physical Aspects of Child Protection ¡ This work has directly informed Systematic Reviews of Physical Aspects of Child Protection ¡ This work has directly informed clinical practice in the Royal College of Radiology/Royal College of Paediatrics and Child Health standards for radiological investigations of suspected abuse NICE maltreatment guideline NHS direct ¡ Advice and guidance to Dental Practitioners http: //www. cpdt. org. uk/ ¡ Production of series of leaflets for all practitioners based on review results ¡ Informed a primary research agenda ¡ Direct influence on practice via our own website visited by 6000 people month from across all disciplines internationally http: //www. core-info. cardiff. ac. uk/

Leaflet produced with NSPCC Leaflet produced with NSPCC

SURE current projects ¡ Collaboration between local health and local government agencies for health SURE current projects ¡ Collaboration between local health and local government agencies for health improvement (Cochrane Protocol) ¡ Intensive Care Monitor Current Awareness Journal ¡ Systematic Reviews of Physical Aspects of Child Protection ¡ Oral Health Specialist Library ¡ Cochrane Public Health Review Group ¡ Literature searching for systematic review on vascular disease ¡ Factors that explain the risk of unplanned hospital admission – a systematic review ¡ Older People’s Wellbeing Monitor for Wales: Evidence Review

SURE Collaborations ¡ Centre for Health and Environmental Research ¡ National Public Health Service SURE Collaborations ¡ Centre for Health and Environmental Research ¡ National Public Health Service ¡ Welsh Assembly Government ¡ Wales Centre for Health ¡ Welsh Institute of Rural Health ¡ Departments within Cardiff University ¡ Universities within UK eg Bristol, University College London ¡ Centre for Evidence Based Dentistry ¡ National electronic Library for Health ¡ National Institute for Health & Clinical Excellence ¡ Centre for Reviews and Dissemination ¡ Virtual Centre for Improving Oral Health ¡ The Cochrane Information Retrieval Methods Group

Finally… “Information is a source of learning. But unless it is organised, processed, and Finally… “Information is a source of learning. But unless it is organised, processed, and available to the right people in a format for decision making, it is a burden, not a benefit. ” William Pollard The Soul of the Firm. Grand Rapids: Zondervan Publishing House 2000

Thank you www. cardiff. ac. uk/insrv/sure mannmk@cf. ac. uk Thank you www. cardiff. ac. uk/insrv/sure [email protected] ac. uk