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  • Количество слайдов: 36

Prof. Hagit Messer-Yaron President, OUI hagitm@openu. ac. il Budapest, April 15, 2013 © Hagit Prof. Hagit Messer-Yaron President, OUI hagitm@openu. ac. il Budapest, April 15, 2013 © Hagit Messer-Yaron, 2013

Universities at the 21 st century “Intellectual and Economic Engines” – Calls for Academia-Industry Universities at the 21 st century “Intellectual and Economic Engines” – Calls for Academia-Industry Partnership © Hagit Messer-Yaron, 2013

University vs. Industry. Contrasting Cultures: University l l l l Corporate Social responsibilities Basic, University vs. Industry. Contrasting Cultures: University l l l l Corporate Social responsibilities Basic, curiosity driven research Create new knowledge Freedom of research Publications & collaborations Sharing of material Open, global community and sharing of research results l l l l Shareholders responsibilities Applied research Develop new products Specific objectives, product focused Ownership and secrecy Control of material Aiming to global market © Hagit Messer-Yaron, 2013

The Death Valley Industry Academia The Death Valley Industry Academia " Death Valley " Products Science © Hagit Messer-Yaron, 2013

Bridging over the “Death Valley” – HOW? Modern relations between universities and industries: l Bridging over the “Death Valley” – HOW? Modern relations between universities and industries: l New venture formation/Spin-offs l R&D agreements l Licensing deals Traditional: l Teaching and students practice l Individual entrepreneurship © Hagit Messer-Yaron, 2013

Industry, university, government Researchers (people!), Faculties, Administration, etc. knowledge university Government money Technology/knowledge. Transfer Industry, university, government Researchers (people!), Faculties, Administration, etc. knowledge university Government money Technology/knowledge. Transfer knowledge industry Entrepreneurs VCs Productions Marketing Management Stocks holders etc. © Hagit Messer-Yaron, 2013 money

The Role of Governments Financial support for academic, basic research. Public support is essential The Role of Governments Financial support for academic, basic research. Public support is essential for academic freedom. 2. Intervention programs for “bridging the gap”. 3. Legal infrastructure: intellectual property rights (IPR) laws, Taxations, innovation law, etc. 1. IPR © Hagit Messer-Yaron, 2013

Lessons from IL experience – How to maintain top level Science together with successful Lessons from IL experience – How to maintain top level Science together with successful High-Tech Industry? © Hagit Messer-Yaron, 2013

R&D statistics (1) The expenditure on civilian research and development (R&D) in Israel over R&D statistics (1) The expenditure on civilian research and development (R&D) in Israel over almost 20 years, 1992 -2011: © Hagit Messer-Yaron, 2013 Source: ISRAEL CBS

R&D statistics (2) The expenditure on civilian research and development (R&D) as a percentage R&D statistics (2) The expenditure on civilian research and development (R&D) as a percentage of the gross domestic product (GDP) - 2009: © Hagit Messer-Yaron, 2013 Source: ISRAEL CBS

R&D statistics (3) The expenditure on civilian research and development (R&D) per capita - R&D statistics (3) The expenditure on civilian research and development (R&D) per capita - 2009: © Hagit Messer-Yaron, 2013 Source: ISRAEL CBS

Israel: Recent Nobel Laureates l Dan Shechtman , Chemistry, 2011 Technion l Ada E. Israel: Recent Nobel Laureates l Dan Shechtman , Chemistry, 2011 Technion l Ada E. Yonath, Chemistry, 2009 Wiezmann Inst. l Robert Aumann, Economics, 2005 HUJI l Aaron Ciechanover, Chemistry, 2004 - Technion l Avram Hershko, Chemistry, 2004 Technion l Daniel Kahneman, Economics, 2002 - HUJI © Hagit Messer-Yaron, 2013

Higher Education in Israel Expanding system l 1989/90: 21 HEI (8 universities + 13 Higher Education in Israel Expanding system l 1989/90: 21 HEI (8 universities + 13 colleagues), 88, 800 students. l 2010/11: 67 HEI, (8 universities + 36 academic colleagues, 23 pedagogical colleagues) 297, 800 students. All HEIs are independent legal entities; All but NBC are heavily supported by the government. © Hagit Messer-Yaron, 2013

The 7+1 universities: • The Technion • The Hebrew University in Jerusalem • Tel The 7+1 universities: • The Technion • The Hebrew University in Jerusalem • Tel Aviv University • Bar Ilan University • Ben Gurion University in the Negev • Haifa University • The Weizmann Institute • The Open University © Hagit Messer-Yaron, 2013

University vs. Colleague HEI PRO Research: Grants, Teaching & research: TT, Faculty, Teaching: Facilities, University vs. Colleague HEI PRO Research: Grants, Teaching & research: TT, Faculty, Teaching: Facilities, Graduate students Undergrad Inst. © Hagit Messer-Yaron, 2013

All Israeli research universities are in the top 500 of the Shanghai list © All Israeli research universities are in the top 500 of the Shanghai list © Hagit Messer-Yaron, 2013

Commercialization of Knowhow. Survey of technology transfer and IP companies 2008 -2009 Approximately 400 Commercialization of Knowhow. Survey of technology transfer and IP companies 2008 -2009 Approximately 400 new patent applications were filed each year in Israel and abroad by the TTCs(approximately 94% of total applications filed abroad). l Commercialization of TTCs focus almost exclusively on inventions. l Most of the revenues from sales of intellectual property (IP) and gross royalties received in 2009 came from Life Sciences and Medicine (approximately 92%). l All the TTCs have affirmed that the main means of protecting IP is applying for a patent. l © Hagit Messer-Yaron, 2013

Commercialization of Knowhow. Survey of technology transfer and IP companies 2008 -2009 (cont. ) Commercialization of Knowhow. Survey of technology transfer and IP companies 2008 -2009 (cont. ) Since their establishment, TTCs have been involved in the establishment of 151 startup companies, of which 44 startup companies are non-operational. l In 2008 -2009, approximately 1, 000 IP invention disclosure reports were submitted by the researchers of various universities for examination by the TTCs; of those, the companies decided to protect approximately 700. l Most commercialization done by the TTCs is to Israeli companies. l Patent distribution by field: l © Hagit Messer-Yaron, 2013

International Comparison l Israel is internationally leading in ID, patents and revenues per researcher International Comparison l Israel is internationally leading in ID, patents and revenues per researcher (about 200 K euro commercialization income per a university researcher) © Hagit Messer-Yaron, 2013

In Israel: l Government’s involvement mainly by intervention programs. l Each university decides on In Israel: l Government’s involvement mainly by intervention programs. l Each university decides on its own policy and regulations independently. However, they share common principles. l Each university has its own TTC. l TTCs are for-profit companies, own by the universities. l TTCs are handling universities IP and are responsible for commercialization, following the university’s policy. © Hagit Messer-Yaron, 2013

IP legislation (and more) in Israel The patent law (1967) defines “service invention” as IP legislation (and more) in Israel The patent law (1967) defines “service invention” as one which has been invented by an employee as a result of his/her service to the employer. l The law doesn’t cover many aspects of academic life, as: students, visitors, sabbaticals, retired stuff, etc. l Thus, universities had to regulate it internally. l No legislation w. r. to industrial R&D projects done in universities. It is up to the parties to agree on the conditions. l In general, government doesn’t claim ownership of publicly sponsored research. l © Hagit Messer-Yaron, 2013

© Hagit Messer-Yaron, 2013 © Hagit Messer-Yaron, 2013

The rules – main common principles: l l l Researchers must disclose to the The rules – main common principles: l l l Researchers must disclose to the university any research of commercial potential. Universities own the IP of “institute inventions” (service invention). Institute inventions are discoveries of employees and others, related to the university. Institute inventions are commercialized solely by the TTC. Commercialization revenues are shared by the inventors (4050%; 50 -60%) and the university. If the TTC chooses not to file for patent, the inventors can do it at their own expense. © Hagit Messer-Yaron, 2013

TTCs in Israel Weizmann Institute Yeda 1959 Hebrew University Yissum 1964 Tel Aviv University TTCs in Israel Weizmann Institute Yeda 1959 Hebrew University Yissum 1964 Tel Aviv University Ramot 1973 1980’s 1990’s © Hagit Messer-Yaron, 2013 1998

Tech. Transfer Company (TTC) mission Identify research results with commercial potential. File for patents Tech. Transfer Company (TTC) mission Identify research results with commercial potential. File for patents and other propriety rights. Actively seek interested commercial entities and sign licensing agreements or establish spin-off companies. Collect royalties. © Hagit Messer-Yaron, 2013

The technology transfer process at TAU “Bridging the Gap” Discovery & Innovation Evaluation Patenting The technology transfer process at TAU “Bridging the Gap” Discovery & Innovation Evaluation Patenting & Marketing Strategy Sponsored Research Business Development IDF Follow Up on Contract Revenues 40 -20 -40 Academic Basic and Applied Research publications © Hagit Messer-Yaron, 2013 To inventors

How does it work? The (best) case of the Weizmann Institute © Hagit Messer-Yaron, How does it work? The (best) case of the Weizmann Institute © Hagit Messer-Yaron, 2013

Responsible technology transfer © Hagit Messer-Yaron, 2013 Responsible technology transfer © Hagit Messer-Yaron, 2013

© Hagit Messer-Yaron, 2013 © Hagit Messer-Yaron, 2013

© Hagit Messer-Yaron, 2013 © Hagit Messer-Yaron, 2013

Selected TT Success Stories: Yeda, Yissum & Ramot (2009) Copaxone | Teva ® Rebif Selected TT Success Stories: Yeda, Yissum & Ramot (2009) Copaxone | Teva ® Rebif ® Total sale of Weizmann based products € 6 Bilion/year | Merck Serono Encryption Algorithm | NDS Gene. Cards Nano. Lub TM TM | Xenne. X | Nanomaterials Exelon | Novartis ® Dunaliella | Nikken Sohonsha Doxil Quantomi. X Erbitux TM TM ® | J&J | QX Capsule | Im. Clone Cherry Tomatoes | Bon. Tom Periochip | Dexcel Lipimix | Tubilux © Hagit Messer-Yaron, 2013

Academic institutions with more than 50 PCTs/year (2004) Univ. of California system Fraunhofer-Gesellschaft CNRS Academic institutions with more than 50 PCTs/year (2004) Univ. of California system Fraunhofer-Gesellschaft CNRS MIT Univ. of Texas California Inst. Tech. Johns Hopkins Univ. of Michigan Columbia Univ. Riken Univ. of Florida Hebrew Univ. Weizmann Institute Stanford © Hagit Messer-Yaron, 2013 297 182 146 131 96 84 76 74 68 67 67 56 54 54

Government’s involvement in university-industry relations l Under the responsibility of the office of the Government’s involvement in university-industry relations l Under the responsibility of the office of the Chief Scientist at the ministry of Industry, Trade and Labor (OCS). l Different intervention programs for university. LOCAL industry collaboration. l Restrictions on internationalization of knowledge created under these programs. © Hagit Messer-Yaron, 2013

Intervention Programs KAMIN 100% 60% 90% © Hagit Messer-Yaron, 2013 Intervention Programs KAMIN 100% 60% 90% © Hagit Messer-Yaron, 2013

Summary Most Israeli Universities had Technology Transfer policy and programs before the BDA of Summary Most Israeli Universities had Technology Transfer policy and programs before the BDA of 1980. l The government has not been involved in the universities TT policy and/or implementation. l IL TT policy is (was) VERY successful, with top universities leading both in academic achievements (e. g. , the Shanghai ranking) and in TT revenues. l The key for success is a RESPONSIBLE technology transfer policy and implementation. l © Hagit Messer-Yaron, 2013

Special THANKS to Amir Naiberg, CEO of Yeda, author of: http: //www. yedarnd. com/images/pics/User. Special THANKS to Amir Naiberg, CEO of Yeda, author of: http: //www. yedarnd. com/images/pics/User. Images/24 h. pdf hagitm@openu. ac. il © Hagit Messer-Yaron, 2013