Occult With No Classic CNV Red-free Photograph

Occult With No Classic CNV

Red-free Photograph Image courtesy of J Slakter

Red-free Photograph l Red-free photograph: shallow subretinal fluid and drusen are seen – There was a small pigment epithelial detachment (PED) noted on clinical examination

Early-phase Fluorescein Angiogram Image courtesy of J Slakter

Early-phase Fluorescein Angiogram l Early phase: an area of irregular hyperfluorescence noted centrally with some surrounding areas of hypofluorescence – The margins of this region are fairly well defined

Mid-phase Fluorescein Angiogram Image courtesy of J Slakter

Mid-phase Fluorescein Angiogram l Mid (venous) phase: the area of hyperfluorescence stands out in better contrast to the more homogenous background fluorescence l Note: there is no increased hyperfluorescence of the lesion typically seen with classic CNV

Mid-late-phase Fluorescein Angiogram Image courtesy of J Slakter

Mid-late-phase Fluorescein Angiogram l Mid-late phase: there is slightly more hyperfluorescence from the lesion at this point

Late-phase Fluorescein Angiogram Image courtesy of J Slakter

Late-phase Fluorescein Angiogram l Late phase: the lesion remains unchanged throughout the later phases of the angiogram, without the increased hyperfluorescence and leakage beyond the margins of the CNV seen with classic CNV – This is an example of occult CNV, likely representing a fibrovascular PED