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Mindstates Conference IV: Technology and Transcendence Psychedelic Psychotherapy Research and Psychedelic Culture Mindstates Conference IV: Technology and Transcendence Psychedelic Psychotherapy Research and Psychedelic Culture

Legal MDMA Psychotherapy Research: First Time in 20 Years DEA started to formally criminalize Legal MDMA Psychotherapy Research: First Time in 20 Years DEA started to formally criminalize MDMA in 1984, emergency scheduled in 1985. • February 2004: FDA, DEA, IRB formally approved MAPS-sponsored research with MDMA -assisted psychotherapy in posttraumatic stress disorder (PTSD). Fear: MDMA Neurotoxicity Claims, Hope: Healing Emotions of Rape, Assault, War.

Psychedelic Research at Harvard: First time in 40 years • 1965: Walter Pahnke completes Psychedelic Research at Harvard: First time in 40 years • 1965: Walter Pahnke completes study looking for placebos for double-blind studies with psilocybin. • 2005: FDA and IRB approval of MDMA for anxiety in advanced-stage cancer patients. • 2006: Proposed LSD/psilocybin cluster headache study. • Fear: Legacy of Leary, Cultural Rebellion • Hope: Healing Fear of Death, Cultural Integration

Private Production of Marijuana: Perhaps First Time in 65 Years • 1937: Marijuana Tax Private Production of Marijuana: Perhaps First Time in 65 Years • 1937: Marijuana Tax Act • 1942: Marijuana Removed from Formulary • 2005: MAPS-coordinated lawsuit: Prof. Lyle Craker v. DEA seeking license for a MAPSsponsored facility at UMass Amherst, • 2005: Dr. Abrams Smoking v. Vaporizing Study • Fear: Marijuana Propaganda, Gateway to Chaos • Hope: Safe, Effective, Inexpensive Medicine

Albert Hofmann Birthday: 100 Years on January 11, 2006 Albert Hofmann Birthday: 100 Years on January 11, 2006

The Vision: Mysticism to Psychedelic Clinics The Vision: Mysticism to Psychedelic Clinics

Images of MDMA over Time From Aid to Meditation To Raves and Holes in Images of MDMA over Time From Aid to Meditation To Raves and Holes in the Head To Life Preserver

Catholic Monk - 1985 • “ A monk spends his whole life cultivating the Catholic Monk - 1985 • “ A monk spends his whole life cultivating the same awakened attitude it gives you. ” Brother David Steindl-Rast Newsweek, April 15, 1985

Jewish Religious Leader-1985 • “You call the Sabbath a delight. It [MDMA] is like Jewish Religious Leader-1985 • “You call the Sabbath a delight. It [MDMA] is like the Sabbath at the end of a long week. ” Philadelphia Rabbi June 1, 1985. Washington Post

Typical Rave “Huggedup. Lovedup Blissedout. ” • Looks positive. Typical Rave “Huggedup. Lovedup Blissedout. ” • Looks positive.

DEA Website Image: What is a Rave? DEA Website Image: What is a Rave?

DEA Website Rave Icon DEA Website Rave Icon

NIDA Postcard 1999 -2003 NIDA Postcard 1999 -2003

Brain Damage Images • Image courtesy of Dr. GA Ricaurte, Johns Hopkins University School Brain Damage Images • Image courtesy of Dr. GA Ricaurte, Johns Hopkins University School of Medicine.

Brain Cell Death • Image courtesy of Dr. GA Ricaurte, Johns Hopkins University School Brain Cell Death • Image courtesy of Dr. GA Ricaurte, Johns Hopkins University School of Medicine.

Leshner Testimony to Senate Subcommittee on Government Affairs 7/30/01: Evidence of Bias in 2005 Leshner Testimony to Senate Subcommittee on Government Affairs 7/30/01: Evidence of Bias in 2005 Political Ad

Brain SPECT Scan-MTV/Oprah Holes in the Brain from MDMA Brain SPECT Scan-MTV/Oprah Holes in the Brain from MDMA

Brain SPECT Scan-MTV/Oprah Holes in the Brain from MDMA Brain SPECT Scan-MTV/Oprah Holes in the Brain from MDMA

Brain SPECT Scan-MTV/Oprah Holes in the Brain from MDMA Brain SPECT Scan-MTV/Oprah Holes in the Brain from MDMA

Brain SPECT Scan-MTV/Oprah Holes in the Brain from MDMA Brain SPECT Scan-MTV/Oprah Holes in the Brain from MDMA

Addicted to Ecstasy Career • Lynn Smith • May 2005, publishes book • On Addicted to Ecstasy Career • Lynn Smith • May 2005, publishes book • On promotional tour • Works for Partnership For a Drug-Free America Despite Holes in the Brain, She walks, talks writes, makes money.

ecstasy…the ugly Ecstasy Eats your Brain ecstasy…the ugly Ecstasy Eats your Brain

Mc. Cann/ Ricaurte Science Paper September 2002 • Preprint sent Dr. Mithoefer for comment. Mc. Cann/ Ricaurte Science Paper September 2002 • Preprint sent Dr. Mithoefer for comment. Title: Severe Dopaminergic Neurotoxicity in Primates after a Single Recreational Dose Regimen of MDMA (Ecstasy). • “It is possible that some of the more recent cases of suspected young-onset Parkinson’s might be related to MDMA exposure but that this link has not yet been recognized.

MDMA Helps Treat Parkinson’s • Tim can perform gymnastic feats while on Ecstasy. • MDMA Helps Treat Parkinson’s • Tim can perform gymnastic feats while on Ecstasy. • BBC Special, Feb 15, 2001

NIDA’s Freevibe Site-11/6/02 • “Ecstasy was invented in a lab by a scientist working NIDA’s Freevibe Site-11/6/02 • “Ecstasy was invented in a lab by a scientist working with the same chemical structures found in methamphetamine. At one time, the drug [MDMA] was used by psychotherapists, before they realized that the drug experience was not easily controlled and was mind-altering. ” http: //www. freevibe. com/headsup/ecstasy. shtml

Washington Post MDMA Article Portrait of Leary Washington Post MDMA Article Portrait of Leary

Israel’s Largest Newspaper March 25, 2005 Israel’s Largest Newspaper March 25, 2005

MAPS Bulletin Cover MAPS Bulletin Cover

Future Potential • Future Potential • "Psychedelics, used responsibly and with proper caution, would be for psychiatry what the microscope is for biology and medicine or the telescope is for astronomy. " • Dr. Stan Grof

Albert Hofmann’s Vision • “I believe that if people would learn to use LSD’s Albert Hofmann’s Vision • “I believe that if people would learn to use LSD’s vision-inducing capability more wisely, under suitable conditions, in medical practice and in combination with meditation, then in the future this problem child could become a wonder child. ”

MAPS as Psychedelic Pharmaceutical Company • MDMA Treatment Manuals • Clinical Monitoring Teams • MAPS as Psychedelic Pharmaceutical Company • MDMA Treatment Manuals • Clinical Monitoring Teams • Therapist Training Program • CME courses • $5 million, 5 year plan for studies

Going Global • • Israel MDMA/PTSD Pilot Study Spain MDMA/PTSD Pilot Study Swiss MDMA/PTSD Going Global • • Israel MDMA/PTSD Pilot Study Spain MDMA/PTSD Pilot Study Swiss MDMA/PTSD Pilot Study German MDE/maybe MDMA Couples Therapy study • Canadian/Mexican Ibogaine Outcome Study

MAPS as Marijuana Pharmaceutical Company • DEA lawsuit for UMass Amherst • Importation from MAPS as Marijuana Pharmaceutical Company • DEA lawsuit for UMass Amherst • Importation from Dutch Office of Medicinal Cannabis • Vaporizer research: non-smoking delivery system v. smoking

MAPS as Community • Conferences • Networking • Books, Publications, Email Forum • Events: MAPS as Community • Conferences • Networking • Books, Publications, Email Forum • Events: Research and Dance Community Alex Grey’s Chapel of Sacred Mirrors 20 th Anniversary of MAPS, 2006

MAPS at Burning Man • Psychedelic Emergency Services for the last two years, again MAPS at Burning Man • Psychedelic Emergency Services for the last two years, again this year. • Fear: Psychedelics as Catalysts of Acute Crisis and Long-Term Mental Illness • Hope: Crisis transformed to Therapy, Psychedelic Community Takes Care of Its Own, Acknowledgement of Risks and Balanced Integration into Society