Mainz — Germany VENUE Thursday 8 th

Mainz - Germany

VENUE Thursday 8 th 1: 00 p. m. EORTC GI board member meeting 2: 00 p. m. Meetings of task force groups Colon cancer / Quality Assurance (only on invitation) Dear Friends and Colleagues, It is our great pleasure to invite you to the autumn meeting of the “EORTCGastrointestinal Tract Cancer Collaborative Group". The primary purpose of this meeting is to accelerate our progress in the fight against GI cancer and to improve our international scientific collaborations between all European countries in this rapidly advancing field. This meeting will be hosted at the Haus Kupferberg at Kupferberg terrace, in close proximity of the University Hospital of Mainz. Here we will bring together all of you, i. e. gastroenterologists, oncologists, surgeons, radio-oncologists, laboratory scientists, pathologists, statisticians, EORTC representatives as well as colleagues from the pharmaceutical industry, providing the opportunity for a maximum of interaction and discussion. Within these two days, you will not only enjoy our hospitality but also be able to attend special social events. On Thursday and Friday evening you will have the opportunity to enjoy the beauty and the charm of the old Roman city of Mainz as well as the German wine garden Rheingau with the well known Eberbach Monastery, one of Europe’s first Cistercian settlements. The Symposium on Saturday morning will be held as official scientific meeting, so that our German and local colleagues can join us in our GI oncology lectures and our studies. 3: 15 p. m. Imaging and pancreas cancer 4: 30 -6: 00 p. m. Translational Research group meeting Sightseeing of Johannes Gutenberg Museum, Mainz Dinner Restaurant Mollers, at Staatstheater Mainz Gutenbergplatz Friday 9 th Scientific Group Meeting 9: 00 -12: 30 Part I (lunch) 1: 30 - 4: 30 Part II 5: 00 - 6: 00 p. m. Business meeting Rheingau Sightseeing and Dinner at Eberbach Monastery These meetings will be located at the Haus Kupferberg, Kupferberg terrace near Dorint Novotel Mainz, in walking distance from central station (Hauptbahnhof) and University hospital Saturday 10 th Scientific Symposium 8. 30 a. m. to 2: 00 p. m. Hotel Hilton, Rheinallee, Mainz SECRETARY Mrs. Simone Becker Tel: +0049 -6131 -176839 - Fax: +0049 -06131 -176621 e-mail: becker@1 -med. klinik. uni-mainz. de We would be delighted if you could attend our EORTC GI group meeting and look forward to seeing you in Mainz/Frankfurt. Sincerely yours Markus Moehler Manfred Lutz Peter R. Galle Wolf O. Bechstein Gastrointestinal Tract Cancer Group

General Information and Services Scientific sessions: The European Organization for Research and Treatment of Cancer GI Group autumn meeting starts on 08 November 2007 and ends on 10 November 2007. Arrival at Mainz (close to Frankfurt (airport): At Frankfurt airport, taxis (~40 -50€ one way) and train services (~10 €) are regularly available directly to Mainz city or Mainz central station. The Frankfurt airport is about a 30 min drive away from Mainz city (Autobahn). Hotel accommodation: We strongly recommend Hotel Römerwall, Hotel Mainzer Hof and Günnewig Bristol Hotel Language: The official language of the meeting is English. Dress code: For the gala dinner – business casual. Any other events – casual. Climate: The weather in Mainz/Frankfurt is continental. Warm clothes are recommended in November (5 o. C). Rain showers may occur. Insurance: The organizers do not accept any responsibility for injuries or losses sustained by persons or personal belongings during the meeting. Participants are therefore strongly advised to carry appropriate travel and health insurance. AGENDA OVERVIEW Thursday 08 th November 13: 00 EORTC GI board member meeting Task forces, QA, TR group meetings 19: 00 Sightseeing of the Gutenberg-Print-Museum Dinner (Restaurant Mollers, Gutenbergplatz 7, Mainz) Friday 09 th November 09: 00 - 12: 30 - 13: 30 - 16: 30 17: 00 - 18. 00 Saturday 10 th October 08: 30 – 14: 00 Group meeting - part 1 Lunch Group meeting - part 2 Business meeting Sightseeing /Dinner of Eberbach monastery Scientific Symposium Hotel Hilton Mainz and Lunch There is a possibility for a guided city tour according to expressed interest. For those who will stay Saturday night, a dinner will be organized. Electricity supplies and telephone services: The two pin connecting plug (220 V) is similar to that used in a major part of EU (except UK). Coffee breaks: Coffee will be served during breaks. Certification of Attendance: Certificate of Attendance will be available at the registration desk. Gastrointestinal Tract Cancer Group

R E G I S T R A T I O N F O R M Hotel reservation form find enclosed YOUR HOTEL RESERVATION Prof. Dr. Family name Adress City Institution Phone Mr. Mrs. Ms. ____First name _______ Country Postal code____ Fax E-mail____ Accompanying person(s) Mr. Ms. Family name SHOULD BE MADE DIRECTLY TO Touristik Center Mainz Brückenturm am Rathhaus 55116 Mainz, Germany Tel: + 49 (0)6131 -286210/2862128 Fax: + 49 (0)6131 -2862155 First name I WANT TO PARTICIPATE TO THE EORTC GI TRACT MEETING IN MAINZ Group meetings (some restricted) Yes No Scientific Symposium Yes No Social event on Thursday evening Yes No Social event on Friday evening Yes No Business meeting (restricted) Yes No Registration form should be sent to: Mrs. Simone Becker Tel: +0049 6131 -17 6839 - Fax: +0049 6131 -17 6621 e-mail: becker@1 -med. klinik. uni-mainz. de Gastrointestinal Tract Cancer Group

Program (preliminary) Innovative Study approaches Innovative Study Endpoints Galle / Popov / Arnold DC-enhanced MRI PFS versus OS Quality of life or clinical benefit International Symposium EORTC GI Group Oberholzer Collette Conroy Innovative Translational Research Endpoints Aust / Lutz / Moehler Chemotherapy Stoehlmacher Targeted therapy Laurent-Puig Imaging Lordick Innovative therapeutic approaches Saturday 10. Nov. 2007 8: 30 a. m. to 2: 00 p. m. Hotel Hilton Rheinallee, Mainz Non-colorectal cancer Lang / Schmidberger / Haustermans Oesophageal cancer Gastric cancer Pancreatic cancer Schuhmacher Roth Van Laethem Colorectal cancer Nordlinger / Van Cutsem / Ruers Sequential versus combination Perioperative therapy Local therapy Rectal cancer Koehne/Folprecht Bechstein Otto Glynne-Jones Other GI cancers Mitry GIST HCC Hohenberger Ducreux