Ma RS Discovery District Overview Presented by

Ma. RS Discovery District Overview ¢ Presented by: Nina Chagnon, ¢ Date: Jan 17 th, 2007

Ma. RS Discovery District ¢ Why does Ma. RS exist? ¢ What is Ma. RS - and what does Ma. RS do? ¢ What makes Ma. RS unique? ¢ What lessons have we learned? Slide 1

An Age of Intense Global Competition For resources, capital and talent And Ontario faces significant challenges: ¢ Ontario is an economic powerhouse, but its economy is largely driven by resource and manufacturing industries. ¢ Ontario faces an historic opportunity to profit from its discovery and innovation. ¢ The issue is not a failure to invest in Ontario’s research agenda; instead, relative to other jurisdictions, we are not as successful at capitalizing on this investment in research through effective commercialization. ¢ Ontario has what it takes to compete on the global stage - world class diversified science, skilled human capital, global reach. Slide 2

The global landscape is crowded Ontario faces intense competition KENDALL SQUARE Slide 3

So how is Ontario going to compete? By embracing a single, fundamental irony: “In a world of global competition, sources of competitive advantage are becoming increasingly localized … true competitive advantage is found within our communities. " Michael Porter Slide 4

The Origins of Ma. RS Concerned that Canada was losing ground, a group of 12 visionaries founded Ma. RS in 2000 to focus the efforts of our research and business leaders on the global innovation challenge. Milestones § Prime pieces of land purchased in downtown Toronto § Early and ongoing support from all levels of government § Significant private sector leadership and financial support § Phase I of the Ma. RS Centre opened in May 2005 § Phase II is in pre-development; target opening in early 2009 § Full suite of programs and services launched in September 2005 Slide 5

What is Ma. RS? ¢ Ma. RS connects the communities of science, business and capital to create a more efficient commercialization marketplace. ¢ The Ma. RS community is built through co-location, catalytic programs and services, and structured networks. ¢ The Ma. RS community is physically anchored in the Ma. RS Centre and extends virtually through the Ma. RS Portal and Ma. RS Networks. ¢ Ma. RS is focused on building globally significant companies from Canada’s foundation of science and technology innovation. Slide 6

The Ma. RS Centre The Physical Platform The Ma. RS Centre is a convergence facility located in the heart of Toronto’s Discovery District, Canada’s largest research cluster. ¢ Phase I of the Ma. RS Centre (700 K sf, or 77 K m 2, in 3 buildings) opened in May 2005, and is home to over 60 organizations: leading researchers, technology transfer groups, SMEs, multinationals, service providers, venture capitalists and networking organizations. ¢ Private sector tenants outnumber public sector tenants 3: 1. ¢ The Ma. RS Incubator (35 K sf, 3. 8 K m 2) is home to 25 promising emerging life sciences and ICT companies. ¢ The Ma. RS Collaboration Centre is a conference venue, while the Ma. RS Venture Group provides hands-on support to companies. ¢ Phase II of the Ma. RS Centre (~1 million sf, 111 K m 2 ) will be added to Phase I platform to create a global address. Slide 7

Phase II The Ma. RS Centre 101 College Street, Toronto Slide 8

Intelligent Building Award Global Think Tank Honours Ma. RS ¢ The Intelligent Community Forum (ICF) announced Ma. RS Centre as the winner of its 2006 Intelligent Building of the Year award. ¢ Ma. RS was recognized for its ability to leverage emerging IP based technologies to offer a fully connected community for both: 8 tenants located physically in the building and 8 a broader stakeholder community connected virtually over broadband networks. Award accepted June 9 th, 2006 New York City www. intelligentcommunity. org Slide 9

So how is different?

1. Ma. RS Tenant Mix Covering the Innovation Spectrum Networking and Commercialization Scientific Research & Support Bio. Discovery Toronto Industry MERCK Where Patients Come First Capital & Services University of Toronto Asset Management Slide 11

2. Ma. RS Discovery District Location Number of Publications by Institution: Uof. T Ranks 3 rd Health Sciences - Number of Publications Indexed by Thomson ISI Top 10 Public AAU and G 10 Institutions - 2000 -2004 Sources: Thomson ISI Canadian University Indicators - Deluxe Edition, 2004 and Thomson ISI U. S. University Indicators - Deluxe Edition, 2004. Slide 12

2. Ma. RS Discovery District Location Number of Citations by Institution; Uof. T Ranks 3 rd Health Sciences - Number of Citations Indexed by Thomson ISI Top 10 Public AAU and G 10 Institutions - 2000 -2004 Sources: Thomson ISI Canadian University Indicators - Deluxe Edition, 2004 and Thomson ISI U. S. University Indicators - Deluxe Edition, 2004. Slide 13

3. Ma. RS Urban Location Connecting the creative and business assets of the city Gardiner Museum of Ceramic Art Royal Ontario Museum University of Toronto Sunnybrook & Women’s College The Ma. RS Centre UHN Princess Margaret Mount Sinai Toronto Rehabilitation Institute UHN Toronto General Hospital for Sick children Art Gallery of Ontario Canadian Opera House Discovery District Financial District Major Banks & Investment Firms Entertainment District Creative & Arts District Slide 14

4. Ma. RS Strategy Convergence Innovation “The early decades of the 21 st Century will be marked by the increased scientific and technological convergence of three fundamental drivers - biotechnology, advanced information technology and nanotechnology [. . . ]. These converging technologies have the promise to achieve tremendous improvements in human capital, innovation, economic performance, and the quality of life“. OECD Slide 15

4. Ma. RS Strategy Convergence Innovation ce sin C Sc Talent s es ien nce Bu Scie eries ity iv reat Capital cov h Dis oug akthr Bre Economic Results Cre ativ e Co mm unit ies Slide 16

4. Ma. RS Strategy A New Approach of Commercialization Results Old Approach = Ca pit al Science Busi ness = • Slower Process • Increased Risk Linear Results BUSINESS = CAPITAL = Increased Speed • Improved Scope • Scalability • SCIENCE Demand-based, outwardfocused innovation • New Approach • Multi-dimensional innovation Synergistic Slide 17

4. The Ma. RS Strategy Educational & Networking Events ¢ Peer to Peer Series 8 ¢ s es ce Sc ien sin Bu ¢ Capital ¢ 8 ¢ Monthly series designed as follow-on to Entrepreneurship 101, with emphasis the business elements specific to starting up a life sciences company Workshops on key topics of interest to technology and life sciences entrepreneurs delivered by industry specialists Public forums and special events and lectures highlighting the wonders and importance of scientific research and creative energy generated by the arts in our community 8 ¢ Sessions featuring leaders with demonstrated expertise and success in their field. Topics will be of general interest to a broad audience of business, science and capital participants. Book Reviews Creative Communities 8 Expert perspectives on the latest science and technology research that is of importance to the corporate and investment community. Sessions feature cross-functional presentations by technology and market-experts. Global Leadership Series 8 ¢ An annual conference that showcases the invention and creativity of leading thinkers in the convergent worlds of science, technology, business, capital, community and the arts. Emerging Technologies Best Practices 8 ¢ Convergence Innovation 8 Lectures for researchers within the Ma. RS Discovery District who have no prior business training. This non-credit course program focuses on key elements related to key topics such as: intellectual property, forming a company, investment capital, marketing etc. Bio-Entrepreneurship 8 ¢ An intimate forum for entrepreneurs to learn from leaders who have demonstrated success in science and technology. These events also provide an opportunity to network with peers and members of the investment community Entrepreneurship 101 8 ¢ Author readings and panel reviews of books and journal articles shaping the future of the innovation economy. Drug Development Discussion Groups 8 An open forum lead by an industry expert geared for researchers interested in in drug development Slide 19

4. The Ma. RS Strategy Ma. RS Venture Group Mandate Assist start-up teams and growth companies in translating research & innovation into commercial success. Programs & Services ¢ Market Intelligence - Access to leading proprietary research on current markets, investors, and competitive and intellectual property landscapes. ¢ Advisory Services - Delivery of timely strategic and tactical business insights through an in-house team of advisors and network of industry experts. ¢ Ma. RS Programs- Production of specialized educational programs for researchers, entrepreneurs and investors aimed at encouraging collaboration, skills development and stronger networks. Goals 1. Convert more discoveries into marketplace successes. 2. Strengthen the commercialization skillset in the community as a whole. 3. Accelerate attrition - validate commercial viability sooner. 4. Amplify economic outcomes of high potential technologies. Slide 20

4. The Ma. RS Strategy Taking Science out; bringing the Arts in Slide 21

5. Ma. RS Networks Strong Regional Partnerships Province of Ontario Edmonton (Toronto) (Ottawa) Ma. RS Landing (Guelph) BC (Waterloo Region) Ma. RS London Calgary (London) Saskatchewan Québec (Hamilton) Halifax Slide 22

5. Ma. RS Networks Helping build international partnerships Global BUSINESS/Global SCIENCE/Global CAPITAL Linking Canada’s Innovation Excellence to International Markets Serving as a Global Address for International Partners ONTARIO TORONTO CANADA Slide 23

Ma. RS Evolution Slide 24

Ma. RS Evolution Opportunities and Challenges ¢ People care about this topic ¢ Serendipity is a powerful force ¢ Ma. RS’ role as a “neutral sandbox” works ¢ The community must own Ma. RS for it to succeed ¢ Under the right leadership, public/private partnerships can be very effective - and work very quickly ¢ Collaboration is the only way for Canada to achieve critical mass, but true collaboration across expert, cultural and geographic divides is not easy ¢ Commercialization is a global activity – we need to raise awareness of Canada’s assets globally and position our companies for international market success Slide 25

Ma. RS Venture Group Select Companies Diginiche ¢ www. octopz. com Web-Based Collaboration Sofware Clay. Tablet Technologies www. clay-tablet. com ¢ Language Translation Workflow Software Skymeter www. appliedlocation. com ¢ Vehicle Location Billing AXS Digital Animation Studio www. appliedlocation. com ¢ Visulization for Film/TV, Pharma, Biotech, Education, Research Accufusion www. accufusion. com ¢ Digital Laser Parts Manufacturing/Repair Platform Slide 26