Lecture organization Introduction Early deterministic effects

Lecture organization

Introduction

Early deterministic effects

Phases of ARS

Haematological response to 3 Gy, whole body exposure

Gastrointestinal (GI) syndrome (8 -30 Gy) Pathophysiology of the GI Syndrome

Phases of Gl syndrome

Systemic effects of GI syndrome

Irradiated lung tissue

Neurovascular syndrome (NVS)

NVS prodromal perıod

NVS latent period

NVS overt clinical picture

ARS Neurovascular Syndrome 16 20 25 30

Trıage of ınjured persons

Measurement of severity

Radiation dose under 5 Gy

Fatal radiation

Change of lymphocyte counts in initial days of ARS depending on dose of acute WB exposure

Medical management of acute radiation syndrome

Therapeutic support for haematopoietic syndrome patient

Infection managment General principles

Isolation

Prevention of infection

Approach to prevent infection in immunocompromised patients

Management of infection

Management of infection

Cytokines

Cytokines

Selected cytokines

Advantages of cytokine therapy

Use of cytokines for treatment of ARS

Initiation and duration of cytokine administration

Cytokine dosage

Contraindication for cytokine treatment

Growth factor therapy for thrombocytopenia

Bone marrow transplantation (BMT)

Indications for BMT

Timing of grafting

Limitations of BMT

Review - I

Review P - II

Review - III

Review - IV