INTRRODUCTION OF THE SONICMED 2006년 POINTECKOREA Inc 301

INTRRODUCTION OF THE SONICMED 2006년 POINTECKOREA Inc. 301 Seoul venture center 647 -26 Dungcun-Dong Gangseo-Gu Seoul, Korea ☎02 -3662 -2669 (FAX)02 -3662 -2303 010 -2668 -7087

1. History of company 2005. 12. 01: Establised 2005. 1. 24 : Obtained ISO 9001: 2000 2006. 6. 01 : Moved into the Seoul high tech Venture bulding through drastic technical evaluation and competition. 2006. 9. 25 : Development of pesonal arthritis curer (SM-6000) was completed. 2008. 4. 11 : Acquired a Certificate of manufacturing and free sale for medical instrument from KFDA (Korea Food & Drug Association) 2009. 12. 30 : Development of pesonal arthritis curer so called SONICMED(Model SM-7000) was completed

2. What is Osteoarthritis? Osteoarthritis is degenerative joint disease and caused by the againg and damaging of the cartilagebetween joints. Also called degenerative arthritis, it is a mid-life disease that accompanies severe pain and at time leads to swallen joints. if ignored, inflammation of the joints will Continue to a state complete damage and surrounding muscles may wither as well. many people regard Osteoarthritis as a natual side effect of againg and do not consider to treat it properly. This will lead to absolute damage of the joints. Therefore signs Osteoarthritis are appearent, you shoud consult with a phycian and engage in active treament such as medication treament, excercise treatment, daily terapy, and ultrasound treatment. Among the various treatment, ultrasound was recognized by the academic society to have exceptional effectiveness in the treatment of osteoarthritis

3. How to treat Osteoarthritis? Medical treatment This the most popular in treatment for Osteoarthritis. However steroidal antiphlogistic agents are a chief elements in medication treatment. Although recently, many drugs less side effect have been developed medication treatment does not provide fundmental treatment for Osteoarthritis. Moreover, because of various side effects, it has been limitations to being an effective treatment method. Physical treatment physical treatment includes method such as themotherapy, electric treatment, and ultrasound treatment. Among the various methods, ultrasound treatment offer not only temporery relief of pain, but also provides regeneration of cartilage tissue through actvation chondrocytes. Reaserch on ultrasound treatment is contiuously conducted for the development of more effective and safe produces.

4. Side effect on various treatment Med. Ication Stomach disorder, enterohemorrhage , the coagulation [clotting] of blood Injection of Steroid It’s impossible to treat for a long time Injection of hyaluronate adaption of only early patient (5 times injection a week. ) Exercise Surgery painful Financial burden and fear for surgery Copyright © 2008 포인텍코리아

5. No side effect-Ultrasonic Ultrasound is a type of sound vibration on a high wavelength an immensely powerful vibration is created. when this vibration set in a certain direction it gives out a short pulse. In the past, the medical field has applied this charaterastic of ultrasound in various surgical and diagnostic situation. Recently, owing to extensive reserch on ultrasonic frequency bands, certain ultrasonic waves are being used to stimilate cell movement, which makes osteoarthritis treatment possible with ultrasound. Activation of chondrocyte and regeration of cartilage tissue is necessary for the treatment of osteoarthritis, and to make this activation possible a high incorporation of GAG and collagen is required .

6. Adaption of Ultrasound Industrial adaption with using purpose. Industrial Ultrasonic cleaner Low level frequency and vey high intensity ultrasound Ultrasonic diagnostor Very high level frequency and very low intensity ultrasound Ultrasonic medical equipment High frequency and low level intensity ultrasound. SONIMED Medical adaption with various Ultrasound intensity. 1 -50 m. W/cm 2 Non-warmming, Non-destructive, Diagonosis equipment 100 m. W/cm 2 ~600 m. W/cm 2 SONIMED 1 -3 W/cm 2 Warmming effect Physical treament 5 -300 W/cm 2 Destructive effect lithotripter (gall, kidney )

7. SONICMED The only one in the world, treat personally. Model Nomber : Eletricity 220 V/60 Hz Power Consumption : 12 W Ultrasonic frequency : 1 MHz Intensity Component parts Private gel, power adapter hard case. manual SM-7000 100 m. W/cm 2 ~600 m. W/cm 2 Dimension : 280 mm x 176 mm x 69 mm Weight : 3 Kg The private SONICMED gel is a water-based product that enhances the efficiency of SONICMED by maximizing the transmission of ultrasonic. It also contains extracts with anti-bacteria, anti-imflammatory and soothing elements such as menthol, kampa, and methyl salicylate, which add a refreshing feeling. Ultrasound enhances the effectiveness of these key elements by allowing them to penetrate deep within the skin. By adding these gel efficiency extracts in the gel, a synergy effect will be created. The efficieny of ultrasound treatment for osteoarthritis is ultimately enhannced.

8. Pass throughout of SONICMED 1. Chondrocyte activation : SONICMED facilitate the activation of chondrocyte deep beneath the skin surface by applying physical force with ultrasound. 2. Regeneration of cartilage tissue : SONICMED prevents osteoarthritis by regenerating cartilage tissue through activation of chondrocyte. 3. Safe application : SONICMED is a self applicable unit that uses a harmless frequency and is free from any antiphlogistic agents. 4. Prevention against osteoarthritis : SONICMED is a exceptional in preventing the common disorder known as osteoarthritis. 5. Improved medication absorptivity: The physical force of ultrasonic waves will increase the transmissivity of consumed medication within the body. This will maximize the effect of medication. (please consult a physican for use with medication) Coyright © 2008 포인텍코리아

9. Effiects of SONICMED stimulate Cartilage tissue 1 Mhz per second and help to increase cartilage cell, Glycoprotein and collagen can synthesize well. ARTICULAR CARTILAGE (Synovial joint etc. ) Bone Synovial fluid Synovial Capsule Cartilag e SONICMED can decrease Inflammation tissue within synovia Bone SONICMED make stabilize synovial membrane so that can Relief pain

10. This Patient need ultrasound treatment SONOCMED Plantar fascitis Lateral epicondylitis (Tennis elbow) Calcific tendinitis of shoulder Delayed union or nonunion of fracture

11. Pain free by SONICMED! SONICMED is ultrasonic medical instrement designed to relife osteoarthritis pain, using the fullest the exceptional advantages and unique charateratic of ultrasound treatment. Pain free ! 1. Shouler joint pain 2. Elbow pain 3. Hands pain 4. Osteoarthritis pain 5. Foot pain 6. Muscle pain

12. Reference KBS (Korea Brodcasting Station) The effect of low intensity ultrasound for osteoarthritis . Secreet of Birth, Old age, Sickness and Death by KBS (2005. 6. 21) Secreet of Birth, Old age, Sickness and Death by KBS(2009. 12. 10)

13. Reference thesis The Korean orthopaedic association academic jornal, 2005. 5 Noninvasive low intensity ultrasound has shown to be an effective means of accelerating bone frature repair in both animal and clinical studies. The effects of utrasound stimulation on bone repair after fibular osteopomy were assessed in a rabbit fibular fracture model. Bilateral closed fiblular fracture are made in skeletally mature male white japaness rabbit. osteoarthritis.

Reference thesis 2 Forytkova LI, Hrazdire and Mornstein V : Effects of ultrasound on DNA synthesis in tumor cells. Uitrasound of Med Biol, 21: 585 -592, 1995. Hadjiargyrou M, Mc. Leod K, Ryaby JP and Rubin C : Enhancement of fracture healing by low intensity ultrasound. Clinical orthpaedic and Related Researh, 355 S : 216 -229, 1998. Huang M-H, Yang R-C, Ding H-j and Chai C-Y : Ultrasound effect on level of stress proteins amd arthritic history in experimental arthritis. Arch phys Med Rehabil, 80: 551 -556, 1999. Lee P, Rho JY and Hasty K : Ultrasound exposure results in up-regulation of sulfated protein production in chondrocyte. 17 th sourthen Biomedical engineering conference, San Antonio, Texas, 1998. Doan N, Reher P, Meghji S and Hariss M : In vitro effects of therapeutic ultrasound on cell proliferation, protein synthesis, and cytokine production by fibroblasts, osteoblasts, and monocyte. j Oral Maxilafac surg 57: 409 -419, 1999

13. Certificate