Infection By Konrad T Juszkiewicz MD MPH DRK

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Infection By Konrad T. Juszkiewicz, MD, MPH DRK Biomedical research and Development LLC. Almaty 23 Oct. 2013

Definition Infection Invasion of a host organism's bodily tissues by disease-causing organisms Their multiplication The reaction of host tissues to these organisms and the toxins they produce

Clasification Based on : Causative agent Symptoms Medical signs Active (Apparent or unapparent, silent, or subclinical) Inactive (latent infections) Acute Chronic

Viral Infection Characteristic Symptoms Systemic: many different parts of the body or more than one body system at the same time; i. e. a runny nose, sinus congestion, cough, body aches etc. Local at times as in viral conjunctivitis, "pink eye" and herpes. Only few viral are painful (herpes). Often itchy or burning

Classic Symptoms of a Bacterial Infection Localized redness Heat Swelling Pain.

Infection Chain of the events The infectious agent Transmission to another host Exit host Enter host Multiply

Entry gates Oral cavity Nose Eyes Genitalia Anus Open wounds Lungs Interstinum

Susceptible to infection weak, sick, malnourished, have cancer diabetic have increased susceptibility to chronic or persistent infections Suppressed immune system

Outcome of Infection The route of entry of the pathogen and the access to host regions that it gains the intrinsic virulence of the particular organism the quantity or load of the initial inoculants the immune status of the host being colonized

Immune system The immune system is a myriad of cells, tissues, and soluble factors that cooperate to defend against foreign invaders.

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