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Idea 8: Increasing R&D How can we leverage existing federal and grant funds to Idea 8: Increasing R&D How can we leverage existing federal and grant funds to grow research and development, especially in technology that reduces cost and improves quality, as well as expand metro Detroit’s life science sector? Gregory Auner, TEAMS Endowed Chair Director Wayne State University SSIM Program

US Health Care Value Chain PRODUCERS PROVIDERS FISCAL INTERMEDIARIES PURCHASERS • Pharmac. & Biotech. US Health Care Value Chain PRODUCERS PROVIDERS FISCAL INTERMEDIARIES PURCHASERS • Pharmac. & Biotech. Manuf. • Medical Device makers & Medical suppliers • Information Technology Firms • Hospitals & Physicians • Integrated delivery network • Pharmacies • Insurers • HMOs • Pharmacy benefit managers • Government • Employers & Individuals • Employer coalitions

Areas of Potential R&D Funding: Automation 1: Admin & Logistics § Administration § All Areas of Potential R&D Funding: Automation 1: Admin & Logistics § Administration § All aspects of workflow, from patient registration to discharge § Logistical systems § Equipment and supplies will be tracked, inventoried, and reordered using RFID (radio frequency identification) technology § § Patients will also be tracked by RFID badges or bracelets, and point-ofcare data from bedside monitors, testing devices, and other sources will be entered automatically into the EMR Software-based workflow and RFIDbased logistics management systems are substantially automated, reducing costs and enabling better service and care for patients HIT Robots

Automation 2: Communication § Free of the mess of personal pagers, overhead pagers, cell Automation 2: Communication § Free of the mess of personal pagers, overhead pagers, cell phones, and desk phones that add cost, clutter, complexity, confusion, and noise to most hospital environments § Personal communication systems § Wireless everywhere

Automation 3: Quality Measurement & Evidence-Based Medicine § Outcomes tracking – essential to gauge Automation 3: Quality Measurement & Evidence-Based Medicine § Outcomes tracking – essential to gauge and constantly improve the quality of care delivered § Integrated with EMR, admin, logistics, … § Vital for evidence-based medicine § Data gathered via the EMR system will be mined for knowledge of what has worked best for patients with a particular medical makeup, history, and condition (MBE— medicine-based evidence) § Full integration of EMR, financial/admin/logistics systems, business intelligence is a major but necessary strategic investment

Automation 4: Telemedicine § Virtual office visits via live interactive video links and vital Automation 4: Telemedicine § Virtual office visits via live interactive video links and vital signs monitors over the Internet § Virtual rounding via fixed or mobile Internet videoconferencing systems § Specialist consultation via fixed or mobile Internet videoconferencing and remote biomonitoring technologies § Telesurgery now possible with Da Vinci § Continual biomonitoring of patient’s vital signs using sensor technologies in the home, or worn on or implanted in the body § Video will be 3 -D/holographic

The Pittsburgh (Good) Example The Pittsburgh (Good) Example

Pittsburgh Life Sciences Greenhouse: IMPACT SINCEPTION § Created 22, 000 sq. ft. lab/office incubator Pittsburgh Life Sciences Greenhouse: IMPACT SINCEPTION § Created 22, 000 sq. ft. lab/office incubator space § Regional life sciences company formation rate has increased from 2 -3 per year to 15 -20 new companies per year § Imported 13 companies to western Pennsylvania § Invested $13. 3 M in VC Funding § Assisted with $18 M in SBIR Funding to regional companies § 6, 000 trainees in biotechnology § Over 5, 000 jobs created

Example of Technological Impact. Cancer Detection § Early and accurate diagnosis of disease is Example of Technological Impact. Cancer Detection § Early and accurate diagnosis of disease is necessary to curtail the burgeoning costs of health care. § The National Cancer Institute estimates the overall costs for cancer in 2006 at $206 billion; $78 billion for direct medical costs and $128 billion for low productivity and premature death. § A 1% reduction in deaths from cancer would be worth $500 billion, approximately 2. 5 times the annual cost of the disease in the US. Statistics from the National Institute of Health

Technology and Engineering Applications for Medicine and Surgery (TEAMS) Detroit Medical Center Childrens Hospital Technology and Engineering Applications for Medicine and Surgery (TEAMS) Detroit Medical Center Childrens Hospital of Michigan Karmanos Cancer Institute Henry Ford Medical Center Detroit VA Hospital Oakwood Hospital System Beaumont Hospital System