Eyeing the future of healthcare David Schafran http

Eyeing the future of healthcare David Schafran http: //Eye. NETRA. com

Problem 2. 4 Billion People w/out Glasses who need them around the world Billions of People with Uncorrected Refractive Error, by 1. 70 Region 1. 6 Billion 2. 4 Billion 1. 80 1. 60 1. 40 1. 20 1. 00 0. 80 0. 60 0. 50 0. 40 0. 20 0. 13 0. 10 0. 02 0. 00 Source: Essilor, Infomarket 2009, CPB Research, numbers may not add due to rounding Emerging Africa & Latin Europe North Asia Middle America East 2

Why? Patients: “Eye care is inaccessible and costly” Eye Care Providers/Vendors: “There’s no easy way to inexpensively or effectively: - Test patients - Deliver eye care products and services” 3

Medical Diagnostic Devices 4

Slit Lamp Exam Retinal Scan 6

Phoropter Reading Charts

Question What if we could create a new platform for eye care that: • • • Is accessible virtually anywhere by almost anyone Produces high quality measurements for eyeglasses that patients can trust Efficiently connects patients to products and services through the mobile network …. all at a low cost? 8

Introducing Eye. Netra Digital ecosystem for eyecare to serve 1 Billion people 9

Introducing NETRA-G Near Eye Tool for Refractive Assessment “Mobile Phone + Software + Eyepiece” 10

Refraction Map using Wavefront Sensor Wavefront aberrometer Shack-Hartmann WS

NETRA = Inverse of Shack-Hartmann wavefront sensor User interactively creates the Spot Diagram Cell. Phone on LCD 1. Displace 25 spots with smart UI 2. Displace spots till single dot perceived Eye. Piece 12 12

300+ DPI LCDs 13

3 Major Innovations • Breakthrough Science • Off the Shelf Components • Piggybacking on Mobile Phone Hardware 14

Split Image Focus

Software replaces moving parts 16

NETRA-G of the near future 17

NETRA-G is a superior refractive testing tool NETRA-G Auto-refractor Phoropter Retinoscope Accurate Economical Portable Minimal training Fast Automatic Networked 18

Awards Clinical Test Partners Press Click Images to view award pages and p 19 articles/vid

NETRA-G UX Testing Worldwide Confidential 20

Mumbai Slum Outreach: Lotus Eye Hospital in Dharavi Mumbai Optical Shop Hyderabad Eye Clinic: LV Prasad Eye Institute Primary vision center Chennai Optical Shop School, Nairobi, Kenya Hyderabad Eye Hospital: LV Prasad Eye Institute Patient’s home, Rio Grande do Sul, Brazil Mumbai Optical Shop 21

Markets: Current Ophthalmic Diagnostics Worldwide: $750 M Eyeglasses Worldwide: $75 B India: $1 B China: $5 B *Device sales only *Eye. Netra will significantly expand this market 22

Disruptive opportunity #1 Underserved Consumers in India and underdeveloped markets Worldwide: 2. 4 B people w/out glasses who need India: > 300 M China: > 400 M Source: Essilor and Procter & Gamble 23

A income drives massive jump A small rise in income = Massive in demand for eyecare in demand for Eyecare 40% 10% Base of Pyramid • Need but no demand • Not affordable • Little access 32 *Source: Essilor Emerging Middle Class • Need and demand • Affordable • Need testing Top of Pyramid • Need and demand • Affordable • Access to testing

Why India • Big Need/Market: 300 M+ without glasses who need them • Underserved: 10 K optometrists for > 1 B people • Demand: 100 K Optical shops demand auto-refractors and quality/low cost glasses • No Regulation on medical devices or prescribing/selling glasses • Good infrastructure: Eyeglasses makers available in major cities • Expertise of founders • Great traction with partners 25

India Opticals Today Vs. Tomorrow Today: Entrepreneurs have to spend a lot of money to open up an optical shop: • • • Autorefractor* - $5000. Large up front cost. Rely on patients coming to store Must have own linkages to fulfillment – difficult to negotiate good rates *Many don’t have testing equipment because of price or lack of trained professional/optometrist. 26

India Opticals Today Vs. Tomorrow: Ø FREE (or low cost) diagnostic Ø High quality product fulfillment included • • • NETRA – G, free or low cost Access to new clients via 1 -800 -EYENETRA call center which funnels and relays testing requests Wireless connection to discounted brand-name lenses and frames 27

Disruptive opportunity #2 Point of care in USA and developed markets 28 28

Product Pipeline: Eyecare Medkit Tablet example 29

Hardware App Store 31

3 d Printing + Maker Spaces Workspace Snapshot 3 d Printer for Prototyping

Cataract Slit Lamp Exam

CATRA: Cataract Screening Tool Vitor Pamplona Erick Passos Jan Zizka Manuel M. Oliveira Everett Lawson Esteban Clua Ramesh Raskar

CATRA: Radar for Cloud Cover Lens Moving patterns on Screen Pinhole Cell Phone Display

Eye is mirror of health 37

Impacting lives of hundreds of millions 38 Disruptive technology | Disruptive business model | Global Social Impact

Symbiotes for Health

Dr. Smartphone Tricorder

Diagnostic/monitoring data + AI Analytics Engines = Predictive Medicine 41

What’s the role of the doc?

http: //Eye. Netra. com

Consumer health Emerging markets AI Analytics cloud POC diagnostics Democratization of Hardware Tricorder XPrize