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Example of real co-funded call: JPND Rainer Girgenrath DLR-PT (Germany) Example of real co-funded call: JPND Rainer Girgenrath DLR-PT (Germany)

Joint Programme – Neurodegenerative Disease Research (JPND) JPND is the largest global ND research Joint Programme – Neurodegenerative Disease Research (JPND) JPND is the largest global ND research initiative led by 28 participating countries EU member states Associated countries Third countries We cannot tackle neurodegenerative diseases by acting as single countries Albania Austria Belgium Canada Croatia Czech Republic Denmark Finland France Germany Greece Hungary Ireland Israel Italy Luxembourg Netherlands Norway Poland Portugal Romania Slovakia Slovenia Spain Sweden Switzerland Turkey United Kingdom

JPND: Joint transnational calls Year Total funding Research Area No. of Projects 2011 € JPND: Joint transnational calls Year Total funding Research Area No. of Projects 2011 € 14 M Harmonization of biomarkers 4 2012 € 17 M Risk and Protective Factors 5 2012 € 9 M Evaluation of Healthcare 6 2013 € 12. 5 M Cross-Disease Analysis 10 2013 € 7 M Preventive Strategies 5 2014 € 0. 5 M Working groups on longitudinal cohort studies 15 Total € 60 M 40

Partnership with the EC: co-funded call • Synergy between JPND and H 2020: JPco-fu. Partnership with the EC: co-funded call • Synergy between JPND and H 2020: JPco-fu. ND • up to € 10 M EC top-up funding • Started in January 2015 • Call on three topics for 2015 (€ 30 M national budget) • Genetic, epigenetic and environmental risk + protective factors • Longitudinal cohorts in ND research • Advanced experimental models of ND

Organisation: Jpco-fu. ND Coordinator: Philippe Amouyel Executive Committee (Ex. Com) WP leader Network Steering Organisation: Jpco-fu. ND Coordinator: Philippe Amouyel Executive Committee (Ex. Com) WP leader Network Steering Committee (NSC) 25 funding organizations Call Steering Committee (CSC) participating organizations Joint Call Secretariat (JCS)

Peer Review Procedure > - 6 months • - 3 months • Call topic(s) Peer Review Procedure > - 6 months • - 3 months • Call topic(s) Call text

Peer Review Procedure Call text • Topic(s) • Participating organizations • Funding duration: 3 Peer Review Procedure Call text • Topic(s) • Participating organizations • Funding duration: 3 yrs. • Size of consortia: 3 -8 • Limitation of research groups from one country: 2 • 2 step review procedure • Review criteria • Eligibility criteria • Earmarked budget • National contact points

Peer Review Procedure > - 6 months • - 3 months • - 2 Peer Review Procedure > - 6 months • - 3 months • - 2 months • Call topic(s) Call text Call procedures Memorandum of Understanding (Mo. U)

Peer Review Procedure Call procedures • Boards/structure • Eligibility • Size of the consortia Peer Review Procedure Call procedures • Boards/structure • Eligibility • Size of the consortia • External collaborators • Revision of a proposal • PRP: composition, declaration • Pre-proposal evaluation: written statements + PRP meeting • Scoring 1 -5, weighting of review criteria • Feedback to applicants • Formal check • PRP/CSC meeting (full proposals) • Time schedule

Peer Review Procedure > - 6 months • - 3 months • - 2 Peer Review Procedure > - 6 months • - 3 months • - 2 months Call topic(s) Call text Call procedures Memorandum of Understanding (Mo. U) • - 1 month Collect potential reviewers Country specific information Proposal template Electronic submission system Frequently asked questions (FAQ) Publication of the call (Call text and documents) •

Peer Review Procedure • 1 month • 2 months 3 months • 4 months Peer Review Procedure • 1 month • 2 months 3 months • 4 months • Reviewers (from all countries) Chair Declaration (confidentiality, conflict of interest) signed Deadline Pre-proposals: 175 Pre-proposals Formal check (corrections within 48 hours) National eligibility check Reviewer assignment (3 per proposal) Written evaluation (scores 1 -5) CSC Meeting/Peer Review Panel (PRP) -> selection of top pre-proposals: 55

Peer Review Procedure Inform applicants, Feedback: Decision/Evaluation text/final scores • 5 months Compile Final Peer Review Procedure Inform applicants, Feedback: Decision/Evaluation text/final scores • 5 months Compile Final Review Board Deadline Full proposals Formal check Reviewer assignment (3 per proposal) Summer break: months 6 + 7 • 8 months PRP Meeting: Final recommendation: 29 Final ranking list CSC Meeting: Funding gaps • 4 months

Peer Review Procedure • 8 months • 9 months • 11 months Funding gaps Peer Review Procedure • 8 months • 9 months • 11 months Funding gaps + possible solutions 1. increase national budget 2. cut budget of funded research groups 3. EC top-up funding 4. reject proposal Final CSC decision Inform applicants Start national funding negotiation first projects start

Consortium agreement • Minimum overall amount that needs to be spent receive max. EC Consortium agreement • Minimum overall amount that needs to be spent receive max. EC contribution of 10 Mio. € is 30 Mio. €. • Failures of funded transnational projects or budget cuts within their duration might reduce the final EU-Top-Up Funding as this will be based on real expense. • The maximum budget available for co-funding of research projects is 7 Mio. € (10 Mio. € - 3 Mio. € management and unit costs). • Australia, Canada, and Switzerland’s budget does not count for calculating the maximum co-funding amount.

Consortium agreement • Goal: maximize the number of high quality proposals to be funded. Consortium agreement • Goal: maximize the number of high quality proposals to be funded. • First explore all funding solutions to unblock situations at the national level. • Each final sum paid by the partners will be topped-up by 10% with EC contribution. If this leads to a situation where insufficient funds are remaining from the EC contribution to fund further projects, this percentage may be revised by the CSC. • A part of the EC contribution will be used to fund partners for which no more national funds are available (filling the gap). • The distribution of remaining funds, if any, shall be discussed and decided during a CSC meeting.

EC top-up budget distribution Partial sums Rank 1 2 3 4 5 6 7 EC top-up budget distribution Partial sums Rank 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Total 1. 136. 622 2. 542. 903 3. 577. 486 5. 027. 905 5. 497. 072 6. 990. 361 8. 175. 481 9. 679. 168 11. 392. 346 11. 917. 146 12. 735. 146 13. 759. 494 14. 359. 554 15. 601. 940 16. 901. 920 17. 912. 098 Country A B 0 0 199. 360 199. 360 0 0 0 0 Country C 198. 000 398. 000 598. 000 798. 000 Country D 0 0 0 0 315. 000 764. 478 925. 466 Country E 0 333 333 494. 321 Country F 249. 600 646. 339 805. 459 1. 117. 959 1. 303. 079 1. 699. 039 1. 859. 039 2. 059. 039 2. 309. 039 2. 509. 039 2. 736. 543 Country G 569. 130 1. 282. 182 1. 817. 274 2. 330. 954 2. 541. 001 3. 021. 221 3. 521. 221 3. 811. 398 4. 223. 598 4. 523. 598 4. 722. 946 4. 923. 026 5. 219. 486 5. 719. 486 6. 002. 160 Possible funding Gap filling in order of ranking

EC top-up budget distribution Reimbursement of at least 10% of actual budget (without AU, EC top-up budget distribution Reimbursement of at least 10% of actual budget (without AU, CA, CH) a. 10 % of actual budget if no gap filling is used b. 0 % if already 10% are used for gap filling c. 1 -9 % if less than 10 % are used for gap filling Total budget e. g. 30. 000 € Actual budget A b c 199. 000 500. 000 650. 000 0 130. 000 29. 000 19. 900 0 36. 000 Additional reimbursement to reach guaranteed reimbursement (%) 10 % 0% 5% Actual reimbursement 10 % 26 % 10 % Gap filling Reimbursement

EC top-up budget distribution We strongly recommend to use the EC money primarily for EC top-up budget distribution We strongly recommend to use the EC money primarily for gap filling -> more funded projects -> more EC top-up money

ERA-NET Cofund EC requirements for co-funded calls • Call text received at least 30 ERA-NET Cofund EC requirements for co-funded calls • Call text received at least 30 days before publication • Call open for at least 60 days • Two-step procedure • Only eligible entities invited to step 2 • At least three independent experts (reviewer) per full proposal • Review criteria: 1. excellence 2. impact 3. quality and efficiency of the implementation • No jumping in the ranking list • Confidentiality

ERA-NET Cofund • a) b) c) d) e) Submit to the EC: Ranking list ERA-NET Cofund • a) b) c) d) e) Submit to the EC: Ranking list Observers’ report Joint selection list Signed commitment on availability of funds Participants and abstracts

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