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Emergency Airway Management Pat Melanson, MD Emergency Airway Management Pat Melanson, MD

Safe airway management airway evaluation n identification of the difficult airway n assessment of Safe airway management airway evaluation n identification of the difficult airway n assessment of other clinical factors n selection of the likely most successful plan of action n reasonable alternative plan n

Algorithmic Approach to Airway Management Have a precompiled plan of airway management ready for Algorithmic Approach to Airway Management Have a precompiled plan of airway management ready for implementation as clinical airway difficulties are encountered n develop a plan and a back-up plan n Practice guidelines for management of the difficult airway n – ASA taskforce – Anesthesiology 78 : 597 - 602, 1993

Emergency Airway n full stomach n altered level of consciousness n deteriorating cardiorespiratory physiology Emergency Airway n full stomach n altered level of consciousness n deteriorating cardiorespiratory physiology n abnormal or distorted upper airway anatomy n no time for pre-assessment or plan

Airway Assessment n compromise or threats n potentially difficult airway Airway Assessment n compromise or threats n potentially difficult airway

The Three Pillars of Airway Management n Patency ( airflow integrity ) n Protection The Three Pillars of Airway Management n Patency ( airflow integrity ) n Protection against aspiration n Assurance of oxygenation and ventilation

Indications for Active Airway Intervention Patency - relief of obstruction n Protection from aspiration Indications for Active Airway Intervention Patency - relief of obstruction n Protection from aspiration n Hypoxic/ hypercapnic respiratory failure n Airway access for pulmonary toilet, drug delivery, therapeutic hyperventilation n Shock n

Clinical Signs of Airway Compromise : Patency Inspiratory stridor n Snoring ( pharyngeal obstruction Clinical Signs of Airway Compromise : Patency Inspiratory stridor n Snoring ( pharyngeal obstruction ) n Gurgling ( foreign matter/ secretions ) n Drooling ( epiglottitis ) n Hoarseness ( laryngeal edema/ vc paralysis) n Paradoxical chest wall movement n Tracheal tug n

Clinical Signs of Airway Compromise : Protection Blood in upper airway n Pus in Clinical Signs of Airway Compromise : Protection Blood in upper airway n Pus in upper airway n persistant vomiting n n Loss of protective airway reflexes

Clinical Signs of Airway Compromise: Oxygenation and Ventilation Central cyanosis n Obtundation and diaphoresis Clinical Signs of Airway Compromise: Oxygenation and Ventilation Central cyanosis n Obtundation and diaphoresis n rapid shallow respirations n Accessory muscle use n Retractions n Abdominal paradox n

The Difficult Airway n Difficult laryngoscopy n Difficult bag-mask ventilation n Lower airway difficulty The Difficult Airway n Difficult laryngoscopy n Difficult bag-mask ventilation n Lower airway difficulty

Techniques for the Compromised Airway Bag-Valve-Mask Ventilation n Endotracheal Intubation n Rapid Sequence Intubation Techniques for the Compromised Airway Bag-Valve-Mask Ventilation n Endotracheal Intubation n Rapid Sequence Intubation n Alternate techniques for the difficult airway n

Golden Rules of Bagging “ Anybody ( almost ) can be oxygenated and ventilated Golden Rules of Bagging “ Anybody ( almost ) can be oxygenated and ventilated with a bag and a mask “ n The art of bagging should be mastered before the art of intubation n Manual ventilation skill with proper equipment is a fundamental premise of advanced airway management n

Frequent Errors with BVM failure to recognize its importance n forget to bag ( Frequent Errors with BVM failure to recognize its importance n forget to bag ( focussed on ETT ) n give up on bagging too early n bag but don’t assess efficacy n failure to assign one person to airway management only n

Difficult Airway : BVM Upper airway obstruction n Lack of dentures n Beard n Difficult Airway : BVM Upper airway obstruction n Lack of dentures n Beard n Midfacial smash n facial burns, dressings, scarring n poor lung mechanics n

Difficult Airway : BVM degree of difficulty from zero to infinite n zero = Difficult Airway : BVM degree of difficulty from zero to infinite n zero = no external effort/internal device n one person jaw thrust/ face seal n oropharyngeal or nasopharyngeal AW n two person jaw thrust / face seal – both internal airway devices n infinite -no patency despite maximal external effort and full use of OP/NP n

Difficult Airway : BVM Remove FB - Magill forceps n Triple maneuver if c-spine Difficult Airway : BVM Remove FB - Magill forceps n Triple maneuver if c-spine clear – Head tilt, jaw lift, mouth opening n Nasopharyngeal or oropharyngeal airway n two-person, four-hand technique n

Prediction of the difficult airway (Intubation) 1200 prospectively studied patients n of 84 patients Prediction of the difficult airway (Intubation) 1200 prospectively studied patients n of 84 patients predicted to have problem, only 22 (25%) actually had a problem n of 43 actual difficult intubations incurred, only 22 (51%) were predicted n – Latto IP. and Rosen M

Prediction of the difficult airway history of past airway problems n Careful physical assessment Prediction of the difficult airway history of past airway problems n Careful physical assessment n knowledge and experience to overcome the "unpredicted difficult airway". n learning practical airway management skills in an environment that is not urgent, stressful or life threatening n

Difficult Airway : Laryngoscopy Short thick neck n Receding mandible n Buck teeth n Difficult Airway : Laryngoscopy Short thick neck n Receding mandible n Buck teeth n Poor mandibular mobility/ limited jaw opening n Limited head and neck movement n – ( including trauma )

Difficult Airway : Laryngoscopy Tumor, abscess or hematoma n Burns n Angioneurotic edema n Difficult Airway : Laryngoscopy Tumor, abscess or hematoma n Burns n Angioneurotic edema n Blunt or penetrating trauma n Rheumatoid arthritis, ankylosing spondylitis n Congenital syndromes n Neck surgery or radiation n

Difficult Airway : Laryngoscopy 3 fingerbreadths mentum to hyoid n 3 fb chin to Difficult Airway : Laryngoscopy 3 fingerbreadths mentum to hyoid n 3 fb chin to thyroid notch n 3 fb upper to lower incisors n Head extension and neck flexion n Mallimpadi classification n Previous history of difficult intubation n

Mallimpadi Classification ( Tongue to Pharyngeal Size ) n I - soft palate, uvula, Mallimpadi Classification ( Tongue to Pharyngeal Size ) n I - soft palate, uvula, tonsillar pillars – 99 % have grade I laryngoscopic view II - soft palate, uvula n III - soft palate, base of uvula n IV - soft palate not visible n – 100% grade III or grade IV views

Unsuccessful Intubation Bag the patient n Maximize neck flexion/ head extension n Move tongue Unsuccessful Intubation Bag the patient n Maximize neck flexion/ head extension n Move tongue out of line of site n Maximize mouth opening n Look for landmarks and adjust blade n BURP maneuver n increasing lifting force n consider Miller blade n Bag the patient n

Dilemmas: Awake or Asleep n Oral or Nasal n Laryngoscopy or Blind Intubation n Dilemmas: Awake or Asleep n Oral or Nasal n Laryngoscopy or Blind Intubation n To Paralyze or Not n

Case #1 43 year old female, day 12 post SAH n 5 unclipped cerebral Case #1 43 year old female, day 12 post SAH n 5 unclipped cerebral aneurysms n vasospasm with left hemiparesis n hydrocephalus with clotted IV drain n rising ICP and BP n decreasing LOC n ate breakfast n

Techniques DL without pharmacologic aids n Awake Direct Laryngoscopy n Awake Blind Nasal n Techniques DL without pharmacologic aids n Awake Direct Laryngoscopy n Awake Blind Nasal n Rapid Sequence Intubation (RSI) n Fiberoptic n Surgical Cricothyroidotomy n

Anesthesia Airway Maxims the awake airway is the safest to manage n spontaneous breathing Anesthesia Airway Maxims the awake airway is the safest to manage n spontaneous breathing is generally safer than paralysis with PPV by mask n have a low threshold to wake the patient up and cancel the case n call for help early n

The “Intubation Reflex “ Catecholamine release in response to laryngeal manipulation n Tachycardia, hypertension, The “Intubation Reflex “ Catecholamine release in response to laryngeal manipulation n Tachycardia, hypertension, raised ICP n Attenuated by beta-blockers, fentanyl n ICP rise possibly attenuated by lidocaine n Midazolam and thiopental have no effect n

Rapid Sequence Intubation : Definition The near simultaneous administration of a sedative-hypnotic agent and Rapid Sequence Intubation : Definition The near simultaneous administration of a sedative-hypnotic agent and a neuromuscular blocker in the presence of continuous cricoid pressure to facilitate endotracheal intubation and minimize risk of aspiration n modifications are made depending upon the clinical scenario n

Rapid Sequence Intubation : Advantages Optimizes intubating conditions/ facilitates visualization n Increased rate of Rapid Sequence Intubation : Advantages Optimizes intubating conditions/ facilitates visualization n Increased rate of successful intubation n Decreased time to intubation n Decreased risk of aspiration n Attenuation of hemodynamic and ICP changes n

Rapid Sequence Intubation : Contraindications n Anticipated difficulty with endotracheal intubation – anatomic distortion Rapid Sequence Intubation : Contraindications n Anticipated difficulty with endotracheal intubation – anatomic distortion Lack of operator skill or familiarity n inability to preoxygenate n

Rapid Sequence Intubation : Procedure Pre-intubation assessment n Pre-oxygenate n Prepare ( for the Rapid Sequence Intubation : Procedure Pre-intubation assessment n Pre-oxygenate n Prepare ( for the worst ) n Premedicate n Paralyze n Pressure on cricoid n Place the tube n Post intubation assessment n

Pre-oxygenate Time - 5 Minutes) ( 100 % oxygen for 5 minutes n 4 Pre-oxygenate Time - 5 Minutes) ( 100 % oxygen for 5 minutes n 4 conscious deep breaths of 100 % O 2 n Fill FRC with reservoir of 100 % O 2 n Allows 3 to 5 minutes of apnea n Essential to allow avoidance of bagging n If necessary bag with cricoid pressure n

Preparation ( Time - 5 Minutes ) ETT, stylet, blades, suction, BVM n Cardiac Preparation ( Time - 5 Minutes ) ETT, stylet, blades, suction, BVM n Cardiac monitor, pulse oximeter, ETCO 2 n One ( preferably two ) iv lines n Drugs n Difficult airway kit including cric kit n Patient positioning n

Pre-treatment/ Prime ( Time - 2 Minutes ) Lidocaine 1. 5 mg/kg iv n Pre-treatment/ Prime ( Time - 2 Minutes ) Lidocaine 1. 5 mg/kg iv n Defasciculating dose of non-depolarizing NMB n Beta-blocker or fentanyl n Induction agent n – Thiopental 3 - 5 mg/kg – Midazolam 0. 1 - 0. 4 mg/kg – Ketamine 1. 5 - 2. 0 mg/kg – Fentanyl 2 - 30 mcg/kg

Paralyze ( Time Zero ) Succinylcholine 1. 5 mg/kg iv n Allow 45 - Paralyze ( Time Zero ) Succinylcholine 1. 5 mg/kg iv n Allow 45 - 60 seconds for complete muscle relaxation n Alternatives n – Vecuromium 0. 1 - 0. 2 mg/kg – Rocuronium o. 6 - 1. 2 mg/kg

Pressure Sellick maneuver n initiate upon loss of consciousness n continue until ETT balloon Pressure Sellick maneuver n initiate upon loss of consciousness n continue until ETT balloon inflation n release if active vomiting n

Place the Tube ( Time Zero + 45 Secs ) Wait for optimal paralysis Place the Tube ( Time Zero + 45 Secs ) Wait for optimal paralysis n Confirm tube placement with ETCO 2 n

Post-intubation Hypotension Loss of sympathetic drive n Myocardial infarction n Tension pneumothorax n Auto-peep Post-intubation Hypotension Loss of sympathetic drive n Myocardial infarction n Tension pneumothorax n Auto-peep n

Succinylcholine : Contraindications Hyperkalemia - renal failure n Active neuromuscular disease with functional denervation Succinylcholine : Contraindications Hyperkalemia - renal failure n Active neuromuscular disease with functional denervation ( 6 days to 6 months) n Extensive burns or crush injuries n Malignant hyperthermia n Pseudocholinesterase deficiency n Organophosphate poisoning n

Succinylcholine : Complications Inability to secure airway n Increased vagal tone ( second dose Succinylcholine : Complications Inability to secure airway n Increased vagal tone ( second dose ) n Histamine release ( rare ) n Increased ICP/ IOP/ intragastric pressure n Myalgias n Hyperkalemia with burns, NM disease n malignant hyperthermia n

Difficult Airway Kit Multiple blades and ETTs n ETT guides ( stylets, bougé, light Difficult Airway Kit Multiple blades and ETTs n ETT guides ( stylets, bougé, light wand) n Emergency nonsurgical ventilation ( LMA, combitube, TTJV ) n Emergency surgical airway access ( cricothyroidotomy kit, cricotomes ) n ETT placement verification n Fiberoptic and retrograde intubation n

Emergency Surgical Airway Maxims they are usually a bloody mess, but. . . n Emergency Surgical Airway Maxims they are usually a bloody mess, but. . . n a bloody surgical airway is better than an arrested patient with a nice looking neck n

Case # 2 42 year old female n right Pancoast tumor n RUL, RML, Case # 2 42 year old female n right Pancoast tumor n RUL, RML, RLL collapse n ARDS on left n hypoxemic respiratory failure n cord compression C 7 - T 4 n