Doctors Gone Bad Human Subject Experimentation (1915 – the present) Torturers Murderers and Despots Martin Donohoe
![“When a doctor [goes] wrong, he is the first of criminals. He has nerve](https://present5.com/presentation/8a13822010cedd97bc4f5ac970e08eec/image-2.jpg "“When a doctor [goes] wrong, he is the first of criminals. He has nerve")
“When a doctor [goes] wrong, he is the first of criminals. He has nerve and he has knowledge. ” - Sherlock Holmes to Dr. Watson, Arthur Conan Doyle
Armenian Genocide (1915 -1917) • Dr Mehmet Resid (Ottoman middle manager, started Butchers’ Brigade) – “Those Armenian bandits were a bunch of harmful microbes pestering the body of this nation. A doctor’s duty is to kill microbes…”
Nazi Medicine • Guiding philosophy = Hegelian (rational utility) • Social Darwinism - parallels in American and British Eugenics Movement – medical journals relatively silent • Ethics reduces morality to efficiency, economics, and aesthetics
Nazi Medicine • An arm of state policy • Focus on racial purity – from eugenic sterilization (370, 000) – to involuntary euthanasia (70, 000) – to large-scale genocide (over 6 million)
Nazi Medicine • Individual worth stated in economic terms; propaganda re obligations to the state – “I Accuse” – “Mathematics in the Service of Political Education”
Nazi Medicine • Doctoring the nation more important than doctoring individuals - Nazism as “applied biology” (Rudolph Hess) • Focus on preventive medicine and public health: antitobacco and anti-alcohol campaigns, environmental toxins, organic farming – to improve Aryan stock • Nazi soldiers given anabolic steroids to increase aggressiveness – cf. professional athletes doping
Nazi Physicians • 52, 000 physicians • National Socialist Party Members • Jewish physicians ostracized/killed/committed suicide; replaced by young Aryans – today 0. 2% of German physicians are Jews, c/w 17% pre-Nazis – 5% of non-Aryan physicians committed suicide; 25% murdered
Nazi Physicians • Economic hard times, physicians salaries rise, academic perks • Blutkitt (“blood cement”)
Nazi “Physician-Researchers” (Torturers) • Dr. Sigmund Rascher - coagulation/amputation studies; hypothermia experiments • Dr. Karl Gebhart: heteroplastic (inter-species) transplantation experiments – c. f. Stalin’s attempts to create interspecies (halfmen/half-apes) “super-warriors” • 2016 – US govt. plans to lift moratorium on funding of certain types of chimeras
Nazi “Physician-Researchers” (Torturers) • Drs. Karl Clausberg and Viktor Brack: Xirradiation/sterilization • Drs. Joachim Mrugowsky, Erwin Ding-Schuler, and Waldemar Hoven: IV phenol and gasoline executions
Nazi “Physician-Researchers” (Torturers) • Dr. Friedrich Wegener (formerly “Wegener’s Granulomatosis”; now granulomatosis with polyangiitis): German pathologist, Nazi party member, autopsied a prisoner with oxygen injected into his bloodstream in an embolism study; may have participated in experiments on concentration camp inmates
Nazi “Physician-Researchers” (Torturers) • Dr Hans Conrad Reiter (formerly “Reiter’s Syndrome”, now “reactive arthritis”): senior Nazi official • Dr. Joseph Mengele: Septicemia/twin vivisection studies • Dr. Hans Eppinger – water deprivation experiments, “father of modern hepatology”
Nazi Medical “Ethicists” • Ethics instruction widespread • Eugen Stähl: Teacher, directed euthanasia program at Grafeneck Castle, where 10, 000 mentally ill patients were gassed and cremated • Rudolf Ramm: author of ethics textbook, editor-inchief of J Germ Med Assn: laid out ethical arguments for “Final Solution” – Executed after conviction by Soviet military tribunal, 1945
“Indirect Participants” • Prof. J Hallevorden: “If you are going to kill all these people at least take the brains out so that the material could be utilized … the more (brains) the better…. I accepted these brains of course. Where they came from and how they came to me was really none of my business. ”
Doctors and Resistance • Pockets of resistance: Catholics, Marxists, Dutch • Drs Eugene Lazowski and Stanislaw Matulewicz created a fake typhus epidemic during the German invasion of Poland (1939) – Germans fooled, quarantined area, many Jews escaped death
Consequences for Physicians • Nuremberg Doctors’ Trials: 23 German physicians tried; 16 found guilty – 7 hanged (incl. Gebhardt, Brack, Hoven, and Mrugowsky) – Hallevorden committed suicide before trial – Rascher died before trial • Ramm executed after conviction by Soviet military tribunal, 1945 • Mengele fled for Argentina (remains verified 1985)
Nuremberg Trials • Otto Ambros (chemist) – invented sarin (nerve gas), convicted of mass murder at Nuremberg Trials, later freed and worked with US chemical industry on thalidomide
Nuremberg Trials
Nuremberg Code • Voluntary consent is absolutely essential • Avoidance of unnecessary physical and mental suffering • Option to quit/responsibility to terminate • Other safeguards
Declaration of Geneva • “I will not permit considerations of religion, nationality, race, party politics or social standing to intervene between my duty and my patient” • “I will not use my medical knowledge contrary to the laws of humanity. ” • “It is unethical for physicians to employ scientific knowledge to imperil health or destroy life. ” • Declaration, respect for protections for health care workers routinely violated throughout world
Declaration of Helsinki • Patients’ rights to respect, self determination, informed decision-making • Investigators’ duties: primacy of subjects’ welfare, ethical considerations take precedence over laws and regulation • Allows for surrogate consent
New Common Rule Provisions (2018) • Improves readability of consent forms • Creates additional exemptions for low risk studies • Eliminates continuing review for others • Requires single-IRB review for multiinstitutional studies conducted in the US
Federal Policy for Human Subject Protection (Common Rule) Revisions • Recommendations: – Studies must not violate domestic and international laws – Voluntary consent absolutely essential – Address special problems and needs of developing countries – Provide treatment and compensation for researchrelated injuries – US must wait sovereign immunity and other procedural obstacles regarding developing country studies
Japanese Abuses in WW II • Extensive biological and chemical weapons program involving prisoners of war • Over 10, 000 doctors and researchers involved (led by Shiro Ishii, Chief Medical Officer of the Imperial Japanese Army)
Japanese Abuses in WW II • “Experiments: ” – Deliberate infections with plague, cholera, typhoid, anthrax, and TB – Testing of drugs and vaccines not previously tested in animals – Surgeries (for training purposes) without anesthesia, followed by vivisection/death – Detonation of bombs, followed by vivisections – Number of victims unclear, likely in six figure range • Subjects referred to as maruta (“logs”)
Japanese Abuses in WW II • Many participants later achieved positions of prominence in Japanese medical schools and societies – E. g. , Tokyo Prefectural University, Olympic Committee, Green Cross, Japanese NIH, and private sector companies
Japanese Abuses in WW II • U. S. government made secret deal with Ishii and top collaborators - 250, 000 yen and immunity from prosecution in exchange for exclusive access to data – Japanese scientists brought to Fort Detrick, MD, to help establish U. S. biological/chemical weapons program
Japanese Abuses in WW II • U. S. government made secret deal with Ishii and top collaborators - 250, 000 yen and immunity from prosecution in exchange for exclusive access to data • Japanese scientists brought to Fort Detrick, MD, to help establish U. S. biological/chemical weapons program – Ishii variously reported in US, South Korea, and Japan; later worked at free clinic for children; converted to Catholicism 1 yr before death from throat cancer in 1967 – U. S. has never apologized for protecting these war criminals
Post-WW II • Over 700 Nazi rocket scientists and their families brought to the U. S. (including Werner von Braun) to help build nuclear missile program – Operation Paperclip
U. S. Immigration Policy • U. S. government excluded Jewish refugees from Nazi Germany from coming to the U. S. in the 1930 s; turned SS St. Louis with 900 Jewish refugees back from Miami )1/3 later murdered by Nazis)
U. S. Immigration Policy • Immigration quotas on “undesirables” throughout 20 th and 21 st Centuries (except when needed for dangerous labor) • Current limits on refugee resettlement, attitudes towards Latinos and Muslims
Post-WW II • Reunification of East and West Germany • US ally • German Medical Association unanimously issues blunt, straightforward apology for its role in the Holocaust (2012)
Post-WW II • US ally • 1950: Science Council of Japan (equivalent to US NAS) vows that Japan “will never pursue scientific research for the purpose of war” – 1967: Extended to broadly proscribe military research
Post-WW II • 2015: Defense ministry starts small program to fund university research with both civilian and military applications • 2017: Massive budget increase • Japanese Constitution (written after WW II) renounces war and use/threat of force to resolve international conflicts – Yet Japan has world’s 7 th most powerful military
Post-WW II Human Subject Experimentation • Dr James Ketchum (psychiatrist), L Wilson Green (scientist), Van Murray Sim – psychochemical warfare studies for US Army – Ketchum later joined faculty of University of Texas Medical School
Post-WW II Human Subject Experimentation: Tuskegee Syphilis Study • Longitudinal study of untreated syphilis in almost 400 African-Americans (and 200 African-Americans without syphilis) • Sponsored by USPHS • Racist assumptions that syphilis behaved “differently” in Blacks
Post-WW II Human Subject Experimentation: Tuskegee Syphilis Study • Mid-1940 s: Penicillin accepted as treatment for all stages of syphilis • By 1972: 28 had died of syphilis, 100 were dead of related complications, 40 wives had been infected, and 19 children were born with congenital syphilis • 1972: Newspaper reports condemn; study ends
Post-WW II Human Subject Experimentation: Tuskegee Syphilis Study • 1970 s: Participants and families compensated by federal government – $9 million settlement – 6, 000 heirs of 600 subjects paid – Living participants who had syphilis paid $37, 000; heirs of deceased participants $5, 000; women and children infected with syphilis got lifetime medical and health benefits • 1997: President Clinton formally apologizes
Post-WW II Human Subject Experimentation: Tuskegee Syphilis Study • “The men’s status did not warrant ethical debate. They were subjects, not patients; clinical material, not sick people. ” – Dr John Heller, Director of Venereal Diseases at PHS between 1943 and 1948 (interviewed in 1976)
Studies on Native Americans • Sterilizations • Radioactive iodine to study adaptation of thyroid gland to extreme cold • Forced removal of children to English language, religious schools (c. f. , Australia, Canada) • Distrust and reluctance of minorities to participate in medical research
Post-WW II Human Subject Experimentation • Guatemala STD study (1946 -8) – U. S. researchers deliberately infected 1, 308 prisoners, military conscripts, prostitutes, orphans (provided by Sisters of Charity), and mental health patients with gonorrhea and syphilis – Scientists treated 87% of those infected (10% later required re-treatment), lost track of 13%
Post-WW II Human Subject Experimentation • Guatemala STD study (1946 -8) – Wives, children, and grandchildren treated, but sexual contacts not traced – Study approved by Guatemalan government • Received material for resource-starved institutions in return – Subjects received cigarettes for participating
Post-WW II Human Subject Experimentation • Guatemala STD study (1946 -8) – U. S. apologized (2010), has pledged $1 million to study research ethics, $775, 000 to fight STDs in Guatemala – Class action lawsuit against U. S. government, Johns Hopkins, Rockefeller Foundation, and Giron (pharmaceutical company) filed on behalf of 700 victims/relatives
Post-WW II Human Subject Experimentation • Guatemala STD study (1946 -8) – Dr. John Cutler (research coordinator): “Unless the law winks occasionally, you have no progress in medicine” – In 1943, Cutler infected volunteer federal prisoners in Indiana with gonorrhea in exchange for cash
Post-WW II Human Subject Experimentation • Guatemala STD study (1946 -8) – After Guatemala, Cutler oversaw the Tuskegee Syphilis Study – Was acting dean at University of Pittsburgh in 1960 s
Post-WW II Human Subject Experimentation • University of Minnesota malaria study (1940 s) • Drs. Thomas Francis, Jr. and Jonas Salk infect psychiatric hospital residents with influenza (? if consent adequate? )
Post-WW II Human Subject Experimentation • Atlanta, Alabama, and Terre Haute prison gonorrhea studies (1940 s and 1950 s) • Study evaluating effects of antibiotics on growth rate (1950 s, Navy recruits, mentally disabled, Guatemalan schoolchildren) • Patuxent prison Asian flu experiment (1957)
Post-WW II Human Subject Experimentation • U. S. govt. -sponsored radiation experiments (e. g. , Strong Memorial Hospital/University of Rochester (NY), Dr Wright Langham) • LSD/sensory-deprivation/electroshock investigations (CIA - MK Ultra)
Post-WW II Human Subject Experimentation • Pentagon/CIA experiments on soldiers and civilians – Edgewood Arsenal Experiments (involving more than 7, 000 soldiers who were exposed to at least 250 biological and chemical agents) • Including sarin, VX, LSD, ritalin • Caused long-term health effects – Deliberate release of Serratia over San Francisco Bay; radioactive cadmium over St. Louis
Post-WW II Human Subject Experimentation • 1963: Dr. Chester Southam injects tumor cells into extremely infirm patients at Jewish Hospital for Chronic Disease in NY without informing them that the shots contain cancer cells – Southam later elected President of American Association for Cancer Research
Post-WW II Human Subject Experimentation • Willowbrook Hepatitis Experiments (1960 s) • Henry Beecher, NEJM (1966) – documented numerous published studies involving ethical breeches (e. g. , non-treatment of strep-infected patients, manipulations under anesthesia, deliberate injection of cancer cells into healthy patients) – little public attention when researchers unmasked in 1991
Post-WW II Human Subject Experimentation • Sterilization programs (70, 000 victims in U. S. ) – Native Americans – Buck v. Bell (USSC, 1927) – WI, NJ, CA, IN, NC, OR, others – Alabama’s Governor Graves vetoed law in 1930 s law citing “hazard to personal rights” – Oregon governor Kitzhaber apologized in 2002 for the over 2500 state-forced sterilizations that occurred between 1917 and 1983 – 2012 – NC to compensate victims
Post-WW II Human Subject Experimentation • Iowa elementary school race experiment (1968; good or bad? ) • Milgram’s obedience studies (1963); Milgram redux (2008) • Soviet psychiatry • US military/pharmaceutical vaccine and medication trials in the developing world
GM foods, biopharmaceuticals • Largest uncontrolled trial in history of humanity • E. g. , Chinese children with vitamin A deficiency used for feeding trials of Golden Rice by Tufts University investigators – Without preceding animal studies – ? Nature of informed consent – May violate Nuremberg Code
Research on Prisoners • Very common historically (infectious diseases, radiation, pharmaceuticals, illicit drugs) • 1905: Cholera experiments on “volunteers” • 1915: Joseph Goldberger – pellagra studies – Prisoners pardoned or paroled in exchange for participation • 1941: Physician William Black infects children with herpes virus, paper published by J Peds • WW II: gonorrhea, gas gangrene, dengue fever, malaria
Research on Prisoners • Pharmaceutical and government sponsored studies on prisoners – 1940 s and 1950 s esp. – Halted in mid-1970 s after drug company executives admitted prisoners were cheaper to use than chimpanzees • Of note, in 2015, the NIH announced its intention to end use of chimpanzees in biomedical research
Research on Prisoners • >90% of pharmaceutical industry research in early 1970 s • Rapidly curtailed by state/federal laws and new university regulations • 2006: IOM approves with safeguards – 2009: 44% of jurisdictions allow compensation
Self-Experimentation • John Hunter (auto-inoculation with gonorrhea and syphilis) • Albert Hoffman (LSD) • Werner Forssmann (right heart catheterization) • Barry Marshall (Helicobacter pylori) • Others
Disturbing Experiments • Inter-species breeding (ape-man, Ilya Ivanovich Ivanov, Guinea, 1927) • Two-headed dog (Vladimir Petrovich Demikhov, 1950 s, Russia) • Monster Study (Wendell Johnson, 1939, University of Iowa) – deliberate induction of stuttering in orphan children
Contemporary Issues and Ethical Dilemmas • 90% of research dollars spent on diseases affecting 10% of the world’s population – Neglected tropical diseases • Research on special populations (cultural minorities, prisoners, developing world, etc. ) • Ghostwriters • Contract Research Organizations • Role of institutional and for-profit IRBs
Contemporary Experiments/Abuses • Unethical use of placebo controls – Various drug trials – Anti-HIV medications and maternal-fetal transmission(sub-Saharan Africa) – Surfactant for neonatal RDS (Brazil, Bolivia) – Hep A vaccine (Thailand)
Contemporary Experiments/Abuses • Trovan/meningitis/Nigeria (control = inadequate ceftriaxone dose) • Chinese organ transplants from extrajudiciallyexecuted enemies of the state (e. g. , Falun Gong, Uighurs)
Contemporary Issues and Ethical Dilemmas • Large majority of phase 3 US drug company trial sites outside US, many in developing countries – Majority of developing nation trial sites without institutional review boards – Victims may seek redress under “Alien Torts Statute” • ICE drugging immigrants for deportation
Contemporary Issues and Ethical Dilemmas • Nerve-sparing clitoroplasty as substitute for female genital cutting – AAP reversal of position (2010) • Kennedy Krieger Institute (Johns Hopkins) lead paint abatement study (1992)
Contemporary Issues and Ethical Dilemmas • Uninsured become research subjects to receive needed care • Human guinea pigs (professional lab rats) – Undermine integrity of study when exaggerate symptoms (25%); pretend they have a health problem (14%); or fail to disclose concurrent enrollment in another study (43%), health problems (32%), prescription drug use (28%) or recreational drug use (20%) – Could be limited by a universal clinical trials participant database, other measures
Contemporary Issues and Ethical Dilemmas • Physicians-in-training (FIRST Study of extended hours – no informed consent for trainees or physicians) • Parent investigators • Neonatal analgesia
Contemporary Issues and Ethical Dilemmas • Only 40% of US citizens have a positive overall impression of clinical trials (2016) – Only 4% of cancer patients enroll in clinical trials each year (2016) • Physician-industry links, proprietary nature of data may deter altruistic volunteers • Under-representation of women and minorities in clinical trials
Contemporary Issues and Ethical Dilemmas • Racial minorities often wary of participation in medical experiments • Most clinical trial participants never informed of trial results • Research Fraud – rare, but damaging to research enterprise • Parachute researchers in developing world
Contemporary Issues and Ethical Dilemmas • Implied vs informed consent (ER research, health information used in subsequent research) • Research by companies using large databases (e. g. , Facebook study on emotional contagion through social networks, OKCupid’s manipulation of compatible “matches”)
Organ Donation • 2009 survey – 50% of adults afraid that physicians will not try as hard to save their lives if they have agreed to donate organs – 44% fear their organs might be sold on the black market • May explain in part why only 45% of U. S. adults have registered as organ donors
Contemporary Issues and Ethical Dilemmas • Informed consent for treatment – physician/patient negotiation vs. unilateral decision-making when treatment options limited • Relaxation of international research standards by eliminating Declaration of Helsinki standards (FDA, 2008)
Contemporary Issues and Ethical Dilemmas • 2003: Ban on industry experiments testing safety of pesticides/other potentially toxic chemicals in humans lifted by NAS and EPA – 2013 – EPA adds safeguards, issues regulations prohibiting studies on pregnant women and children • Monsanto’s Roundup purchased by US government for aerial spraying in Colombia as part of “War on Drugs”
Contemporary Issues and Ethical Dilemmas • 2008: Former director of UCLA School of Medicine’s donated body program pleads guilty to 5 year scheme to sell donated body parts to medical, drug, and research companies, netting more than $1 million
Contemporary Issues and Ethical Dilemmas • Clinical Trials Registry – Drug company noncompliance – Important, since 1/3 of clinical trials conducted in U. S. never published • Massive increase in certain drug prices • Physicians doping professional/Olympic athletes
What to do with data acquired via unethical means? • Eduard Pernkopf’s Atlas; Dachau Hypothermia Experiments; Phosgene gas experiments; biological weapons data (offensive vs. defensive) • Japan’s Unit 731 and biological warfare experiments
What to do with data acquired via unethical means? • Move to rename “Hallevordan-Spatz syndrome”: “pantothenate kinaseassociated degeneration” or “neurodegeneration with brain iron accumulation” • Breast cancer cure scenario
What to do with data acquired via unethical means – AMA Policy E-2. 30 – Adopted 1998 • All proposed experiments using human subjects should undergo proper ethical evaluation by a human studies review board before being undertaken. • Responsibility for revealing that the data are from unethical experiments lies in the hands of authors, peer reviewers, and editors of medical texts that publish results of experimental studies.
What to do with data acquired via unethical means – AMA Policy E-2. 30 – Adopted 1998 • Each publication should adopt a standard regarding publication of data from unethical experiments. • If data from unethical experiments can be replaced by existing ethically sound data and achieve the same ends, then such must be done.
What to do with data acquired via unethical means – AMA Policy E-2. 30 – Adopted 1998 • If ethically tainted data that have been validated by rigorous scientific analysis are the only data of that nature available, and such data are necessary in order to save lives, then the utilization of such data by physicians and editors may be appropriate. • Should editors and/or authors decide to publish an experiment or data from an experiment that does not reach standards of contemporary ethical conduct, a disclaimer should be included. Such disclosure would by no means rectify unethical conduct or legitimize the methods of collection of data gathered from unethical experimentation.
What to do with data acquired via unethical means – AMA Policy E-2. 30 – Adopted 1998 • This disclaimer should: – (1) clearly describe the unethical nature of the origin of any material being published – (2) clearly state that publication of the data is needed in order to save human lives – (3) pay respect to the victims – (4) avoid trivializing trauma suffered by the participants – (5) acknowledge the unacceptable nature of the experiments – (6) endorse higher ethical standards.
What to do with data acquired via unethical means – AMA Policy E-2. 30 – Adopted 1998 • Based on both scientific and moral grounds, data obtained from cruel and inhumane experiments, such as data collected from the Nazi experiments and data collected from the Tuskegee Study, should virtually never be published or cited. • In the extremely rare case when no other data exist and human lives would certainly be lost without the knowledge obtained from use of such data, publication or citation is permissible. • In such a case, the disclosure should cite the specific reasons and clearly justify the necessity for citation.
What to do with data acquired via unethical means – AMA Policy E-2. 30 – Adopted 1998 • Certain generally accepted historical data may be cited without a disclaimer, though a disclosure of the ethical issues would be valuable and desirable.
Ethical Perspectives on Scientific Research and War • Denial of moral responsibility for consequences • Recognition of moral responsibility but competing obligations • Recognition of moral responsibility and refusal to participate • Responsibility to inform or lead public opinion • Publication of research on dangerous/novel pathogens
Scientists and War Research • Archimedes, da Vinci, Galileo, Haber, Fieser • Farraday • Nobel, Einstein, Szilard
Fritz Haber (Physical Chemist) • Played major role in development of chemical warfare in WWI • In violation of Hague Convention of 1907 • “During peacetime a scientist belongs to the world, but during wartime he belongs to his country”
Fritz Haber (Physical Chemist) • 3 future Nobel laureates served in his unit, which developed Zyklon A (insecticide used in gas chambers) • Irony: Jewish, fled Germany in 1933, ultimately took position at what is now the Weizmann Institute in Israel
Doctors as Terrorists • Pediatrician George Habash – founder of Popular Front for the Liberation of Palestine – Behind aircraft hijackings of Black September (1970) • Dr. Fathi Shiqaqi – founder of Palestinian Islamic Jihad (1981) • Ikuo Hayashi – chief of circulatory medicine at a leading Japanese hospital – Pleaded guilty to planting sarin gas on Tokyo subway (1995)
Doctors as Terrorists • Dr Bilal Abdullah convicted in bungled Heathrow Airport car bombing (2007) • Psychiatrist Major Nidal Hasan – awaiting trial for Fort Hood shootings (2009) • Humam Khalil Abu-Mulal al-Balawi: Jordanian suicide bomber, killed 7 CIA agents in Afghanistan (2009)
Doctors as Murderers • Radovan Karadzic (psychiatrist) – former leader of Bosnian Serbs - convicted by International Criminal Tribunal for war crimes against Bosnian Croats and Muslims (2016) • Ayman Al-Zawahiri – leader of Al Qaeda • Bashar al Assad (Syrian President, ophthalmologist) – bombings of civilians and hospitals, use of sarin nerve gas, has killed hundreds of thousands of Syrians
Doctors as Murderers • H. H. Holmes, - "the torture doctor, " • Linda Burfield Hazzard - "the starvation doctor" • Marcel Petiot
Doctors as Murderers • Harold Shipman (British) – world’s most notorious serial killer (250 -400 victims) • Michael Swanger (American - 60 victims) • Harry Bailey (Australian - 75 victims)
Doctors as Murderers • South African cardiologist Wouter Basson (aka “Dr. Death”) – ran “Project Coast” in 1980 s (clandestine military program linked to chemical and germ warfare, assassinations, poisonings, kidnapping, and plots to sterilize the country’s black population) – Found guilty of unethical conduct (2013) • Dr. Farid Fata – ordered chemotherapy for patients on deathbed, in remission, with fabricated cancer diagnoses • Others
Physician Criminals • Violent crimes, including rapes of patients • Performance of unnecessary, dangerous procedures • Illegal opioid distribution • Medicare fraud, kickback scams • Ethical violations through participation in executions
Doctors as Racists • Long history • Common slave era diagnosis = drapetomania – The tendency to run away • More recent: – Ophthalmologist John Taunton – antiimmigrant, white supremacist – Controversy over statue of J Marion Sims (father of modern Ob/Gyn) in NYC
Death Penalty • Racist • Ineffective as a detterant • Numerous exonerations
Doctors and the Death Penalty • Electric chair - invented by dentist Alfred Southwick • Lethal injection - developed by anesthesiologist Stanley Deutsch • Death cocktail (3 drug regimen developed by pathologist Jay Chapman : – Anesthetic (sodium thiopental) – Paralytic agent (pancuronium) – KCl (stops heart)
The Death Penalty and Health Professionals • AMA, APHA, ANA, and ABA (anesthesiologists) oppose participation of health professionals in executions • Only 7/35 death penalty states incorporate AMA ethics policy, including barring doctors from taking an active role in the death chamber
The Death Penalty and Health Professionals • Some states provide immunity to doctors participating in executions by preventing medical boards from taking disciplinary action against them • Many states also provide anonymity
The Death Penalty and Health Professionals • 2001: – 3% of physicians aware of AMA guidelines prohibiting physician participation – 41% would perform at least one action in the process of lethal injection disallowed by AMA
The Death Penalty and Health Professionals • Country’s leading executioner, Dr. Alan Doerhoef (40 lethal injections), acknowledges mistakes in “transposing numbers, ” reprimanded by Missouri for not disclosing malpractice lawsuits
The Death Penalty and Health Professionals • 2008: Director of Health Services for WA state prison system resigns to protest execution • 2009: NC Supreme Court overturns 2007 NC Medical Board ban on physician participation in executions
The Death Penalty and Health Professionals • 2012: Medical Association of Georgia (President = former AMA President Donald Palmisano) refuses to sanction involvement of Dr. Carlo Musso in lethal injection death
Torture • Physician participation in “War on Terror, ” Abu Ghraib, Guantanamo, Black Ops sites – “Basic Science Consultation Teams” – Co-optation of anthropologists in Iraq, Afghanistan – Nurses injecting psychotropic drugs to forcibly sedate deportees – AMA, AAP, APA oppose physician involvement in interrogation/torture
Torture in the War on Terror • Doctors involved in torture, extraordinary renditions – Design torture methods that do not leave physical evidence – Monitor health of detainees to prolong interrogations – Falsifying medical records and death certificates – Carrying out torture – Between 1975 and 2015, 85 doctors in 16 countries were punished for abetting torture or war crimes; hundreds more unpunished (See http: //doctorswhotorture. com/ )
Torture in the War on Terror • CIA report (2014) describes horrific torture, which was not valuable in obtaining any significant information • American Psychological Association rewrote ethics code to allow psychologists to participate, later apologized – APA president-elect during rewrite called international laws against torture a “distraction” to ethics guidance
Torture in the War on Terror • More than 80 % of interrogation between 2005 and 2008 outsourced to Mitchell Jessen & Associates, Spokane, WA for $81 million – Run by psychologists James Mitchell and Bruce Jessen (each paid $1 million by CIA and provided with legal counsel and indemnity agreement for non-prosecution of potential criminal activity) • Investigations, outcry, but no real consequences
Torture • Does not obtain helpful information • Causes resistance to cooperation and increases probability of false confessions (which can divert resources/personnel away from actual threats) • Increases likelihood that torture will be used on U. S. soldiers and citizens; damages U. S. moral credibility; creates new enemies • Persuasion with potential for mutual gain more effective
War on Terror • Capture of Osama bin Laden involved (unsuccessful) sham CIA hepatitis B vaccination project to collect DNA (violation of public trust, has harmed international efforts to eliminate polio and put health care workers lives at risk) – White House has pledged to end program • USAID social media program designed to overthrow Cuban government – 2017 – relations to be “normalized”
The role of the doctor in society • World Health Organization: – “The role of the physician … in the preservation and promotion of peace is the most significant factor for the attainment of health for all. ”
Ethical Issues Relating to Mixed Agency of Military Physicians • • • Triage and return to combat Confidentiality Communication Loyalties/Command Experimentation “The Sea and Poison”
Medical Education Lacking • 2007 survey: 5, 000 medical students at 8 medical schools, 35% response rate (Int J Hlth Serv 2007; 37(4): 64350) • 94% received < 1 hr. instruction on military medical ethics • 3. 5% aware of legislation already passed making a “doctors’ draft” possible • 34% did not know Geneva Conventions require physicians to treat the sickest first, regardless of nationality
Medical Education Lacking • 34% not aware Geneva Conventions prohibit ever threatening or demeaning prisoners or depriving them of food or water • 34% could not state when they would be required to disobey an unethical order (answer = always)
Ethical Issues Relating to Mixed Agency of Civilian Physicians • Physician participation in torture and executions – Most torturers never identified/held accountable – 2008 study at University of Illinois at Chicago • 35% of medical students said torture could be condoned under some circumstances • Pharmaceutical company provision of agents used in lethal injection executions
Trump Administration • Racism, xenophobia, misogyny, classism, homophobia, disorder, international noncooperation (and disruption of alliances) – President narcissistic, sociopathic, ecocidal, acknowledged sex offender, ignorant, unstable, and dangerous • Rise of alt-right, neo-Nazis, KKK, etc. • New era for potential human rights violations at home and abroad
Primo Levi “A country is considered the more civilized the more the wisdom and efficiency of its laws hinder a weak man from becoming too weak or a powerful one too powerful. ”
The role of the doctor in society • Public health versus individual health • Roles, responsibilities, and obligations – patients – society – institutions – families – government – world
The role of the doctor in society • Theodore Billroth: – “If the whole of Social Medicine needs to be part of the curriculum of the medical student, it must not take more than two hours per semester … during the last two semesters; otherwise, it will surely be detrimental to his other studies”
The role of the doctor in society • Rudolph Virchow: – “Doctors are natural attorneys for the poor … If medicine is to really accomplish its great task, it must intervene in political and social life…”
Contact Information Public Health and Social Justice Website http: //www. phsj. org martindonohoe@phsj. org
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