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Course-AS 1 Ltd. - Adaptive Medical Systems AS_GSV Stations for Processing & Visualization of Course-AS 1 Ltd. - Adaptive Medical Systems AS_GSV Stations for Processing & Visualization of HR Medical Images Exit

Contents: About Course-AS 1 Ltd. 2 D Processing & Visualization - General Elements of Contents: About Course-AS 1 Ltd. 2 D Processing & Visualization - General Elements of AS_GSV Stations - Real Time Stream Processing - Real Time Zoned Processing AS_GSV Stations General Options AS_GSV Stations Advantages Types of AS_GSV Stations Summary

Course-AS 1 Ltd. - Adaptive Medical Systems http: //www. course-as. com http: //www. course-as. Course-AS 1 Ltd. - Adaptive Medical Systems http: //www. course-as. com http: //www. course-as. ru Founded in 1993 in Moscow, Russia. Focuses on developing new technologies and systems in the following areas: • • 2 D processing for HR (High Resolution) medical images Specialized computer systems for radiology Multi-machine Parallel Calculations Chips-2 D for processing HR images __Course-AS 1 Ltd. - Adaptive Medical Systems__ Office 427 B, Business Park “Rumiantsevo”, MO, G. P. Moscow, 142784, Russian Federation. Mikael Abgaryan, Ph. D. Director E-mail: abgaryan@course-as. com WEB: www. course-as. com www. course-as. ru (Full version) Tel/Fax: +7 (499) 550 -5096 +7 (499) 550 -7682

Course-AS 1 Ltd. Professional, High Quality and Fast 2 D Processing & Visualization for Course-AS 1 Ltd. Professional, High Quality and Fast 2 D Processing & Visualization for HR Medical Images

2 D Processing & Visualization for HR Medical Images High-Speed Hardware/Software 2 D Conveyor 2 D Processing & Visualization for HR Medical Images High-Speed Hardware/Software 2 D Conveyor based on Original Mathematical Processing of entire frame or in chosen Zones consisting of: • 2 D Conveyor Hardware functions of visualization and some of processing elements in the graphic adapter (2 D-Visualization) • Sequence 16 b software functions the 2 D Software Conveyor frame image processing (2 D-Processing) • Image Frame (DICOM Image) - the minimal part of information for 2 D-Visualization and 2 D-Processing Conveyor Principle of Work 2 D Processing & Visualization: Primary DICOM Images in Computer Memory Scenario Visualization 2 D-Technology The 16 bit Conveyor for 2 D Processing 2 DVisualization • Processing Scenarios - sequence of types and processing cycles with a Parameter Settings

General Elements of AS_GSV Stations • Professional 2 D Processing & Visualization for DICOM General Elements of AS_GSV Stations • Professional 2 D Processing & Visualization for DICOM Systems • Real Time Dynamic Stream 2 D Processing (XA, RF) of 16 b images (up to 60 fps of a format 1 k*1 k) • Real Time Dynamic Stream 2 D Subtraction (DSA) • of 16 b images (up to 30 fps of a format 1 k*1 k) • Real Time Dynamic Zoned 2 D Processing of 16 b series and single frames • Preprint Processing & Viewing for printing of processed images • Graphical Data. Base – as Graphical Patient’s History • The Navigator for Operation with DICOM files in Graphical Data. Base • Patient Data House and Graphical Data. Base PDF file

Real Time Stream 2 D Processing Series Frames (Modality) AS, XA, DSA, RF, DF, Real Time Stream 2 D Processing Series Frames (Modality) AS, XA, DSA, RF, DF, VF, CT, MR, PT, US, EC, CD, DD • Angiographic series (AS, XA, DSA) Slides Film 1 Film 2 Film 3 Film 4 – Screen shots of processing – Primary 10 b DICOM series – DICOM representation of series – Nonlinear Processing 10 b DICOM of series – DSA mode (Subtraction) • Radiological series (RF, DF, VF, CR, RG) Slides – Screen shots of processing Film 1 – Processing of 8 b DICOM series • Tomography series (CT, MR, PT) Slides – Screen shots of processing Film 1 – Viewing 3 D reconstruction of device CT • Ultrasound series (US, EC, CD, DD) Slides – Screen shots of processing

Real Time Zoned 2 D Processing Series and Single Frames (Modality) CR, RF, RG, Real Time Zoned 2 D Processing Series and Single Frames (Modality) CR, RF, RG, MG, XA, CT, MR, SC • Angiographic series (AS, XA, DSA) Slides – Screen shots of processing Film 1 – Processing in a circular zone Film 2 – Processing in an elliptic zone • Tomography series (CT, MR, PT) Slides – Screen shots of processing Film 1 – Processing CT series of a human body Film 2 – Processing CT series of a lower jaw • Radiological series (RF, DF, VF, CR, RG) Slides – Screen shots of processing

AS_GSV Stations General Options • 16 b Professional Tool for qualitative improvements of medical AS_GSV Stations General Options • 16 b Professional Tool for qualitative improvements of medical images · PC Stations AS_GSV series for 2 D Processing and Visualization of all types of DICOM files for: • • • X-Ray diagnostics Angiographic research Computer Tomography Nuclear-Magnetic Resonance Tomography Ultrasonography Other kinds of diagnostics based on DICOM images · AS_GSV Stations operations with DICOM files received from devices of different manufacturers: General Electric, Philips, Siemens, Picker, Kodak, Toshiba, Camtronics, Infi. Med, Acuson, ATL, Hewlett-Packard ect.

AS_GSV Stations General Options • Interactive Visualization of the processing series for: • displays AS_GSV Stations General Options • Interactive Visualization of the processing series for: • displays on operational and viewing monitors • displays in clinical and consultation facilities • displays at symposiums and conferences • The Authorized Access of users from any AS_GSV station connected to the Graphical Data. Base for: • visualization of DICOM primary data • independent processing of DICOM series for visualization • visualization of the series processed earlier by other users • Recording to Optical CD / DVD : • recording on DVD-RAM in the Archive for Patient Data House • processing results and primary DICOM files • Fine Quality Printing of the processed images on high resolution PC Printers without using of expensive DICOM printers

AS_GSV Stations Advantages • Processing always only in the 16 b resolution for Gray AS_GSV Stations Advantages • Processing always only in the 16 b resolution for Gray images (65536 gradation gray) • Real Time Dynamic Processing of primary Angiographic series, switching to DSA mode • Exclusive Real Time Zone Processing of single or serial frames • Professional High Speed Visualization based on the Scenarios Professional Visualization unattainable on PACS systems

AS_GSV Stations Advantages • The Professional Intuitive 16 b Real Time Tools for management AS_GSV Stations Advantages • The Professional Intuitive 16 b Real Time Tools for management & control of image processing • Automatic creation of Processing Scenarios as a result of manipulations by users • Instant adjustment of conveyor processing and visualization based on created Scenarios • Rapid response to change of processing parameters or conveyor elements High Speed and simplicity of high quality visualization

AS_GSV Stations Advantages • All operations with DICOM files are conducted under the control AS_GSV Stations Advantages • All operations with DICOM files are conducted under the control of Graphical Data. Base (GDB) • Viewing and Grouping of DICOM files in a series with subsequent import in GDB • Unlimited number of users at simultaneous work with the same series • Adjustable Options of GDB operations and access rights of users Simplicity and high speed navigations

Advantages of Systems based on the AS_GSV Stations • Integration of AS_GSV Stations in Advantages of Systems based on the AS_GSV Stations • Integration of AS_GSV Stations in PACS system as Professional Stations for 2 D Processing • AS_GSV Stations can be used as Base Stations for newly created PACS systems • Allocation of AS_GSV stations in a Network of 2 D Professional Processing Images • Scalability of Systems to include a range from one office or division up to clinical HIS/RIS • Patient Data House volume minimization will be achieved by saving only DICOM primary data Simplicity of realization of HIS/RIS clinical system

Advantages of Systems based on the AS_GSV Stations • Base upon a 64 b Advantages of Systems based on the AS_GSV Stations • Base upon a 64 b hardware platform – IBM Intelli. Station A-Pro • Easy transition to a 64 b Operational System without replacement of base computers • Opportunity to modernize by adding of PCI-X Professional Graphic Adapters with HR-monitors • Essential Cost Reduction of diagnostic workstations and PACS systems Total Ownership Cost (TCO) reduction of medical diagnostic systems

Types of AS_GSV Stations • Dual monitor AS_GSV-1 k Station for dynamic frames up Types of AS_GSV Stations • Dual monitor AS_GSV-1 k Station for dynamic frames up to 1 k*1 k for angiographic, radiological and tomographic research 1 x. Opteron 2. 2 GHz, 1 GB DDR ECC Registered (up 2 GB), 36 GB System HDD SCSI, DVD-RW Plextor Ext, 1 Gb Ethernet (up 10 Gb Infini. Band), 19” RGB CRT 1600*1200*32 b/(75 -85)Hz, 21” RGB CRT 1600*1200*32 b/(75 -100)Hz for Images, Windows XP Professional & SP 1, Library MIL v 5. 0, Software AS_GSV-1 k • Dual monitor AS_GSV-2 k Station for dynamic frames up to 2 k*2 k for angiographic and radiological research of the high resolution 2 x. Opteron 2. 2 GHz, 2 GB DDR ECC Registered (up 4 GB), 36 GB System HDD SCSI, DVD-RW Plextor Ext, 1 Gb Ethernet (up 10 Gb Infini. Band), 19” RGB CRT 1600*1200*32 b/(75 -85)Hz, 21” RGB CRT 2048*1560*32 b/(75 -85)Hz for Images, Windows XP Professional & SP 1, Library MIL v 5. 0, Software AS_GSV- 2 k • Dual monitor AS_GSV-4 k 2 Station for static frames larger than 2 k*2 k for radiological research of the super high resolution 2 x. Opteron 2. 2 GHz, 2 GB DDR ECC Registered (up 4 GB), 36 GB System HDD SCSI, DVD-RW Plextor Ext, 1 Gb Ethernet (up 10 Gb Infini. Band), 19” RGB CRT 1600*1200*32 b/(75 -85)Hz, 21” B&W CRT 2560*2048*32 b/(50 -75)Hz for Images, Windows XP Professional & SP 1, Library MIL v 5. 0, Software AS_GSV- 4 k 2 • Three monitor AS_GSV-4 k 3 Station for static frames lager than 2 k*2 k for radiological research of the super high resolution and viewing rooms 2 x. Opteron 2. 2 GHz, 2 GB DDR ECC Registered (up 4 GB), 36 GB System HDD SCSI, DVD-RW Plextor Ext, 1 Gb Ethernet (up 10 Gb Infini. Band), 19” RGB CRT 1600*1200*32 b/(75 -85)Hz, 2 x 21” B&W CRT 2560*2048*32 b/(50 -75)Hz for Images, Windows XP Professional & SP 1, Library MIL v 5. 0, Software AS_GSV- 4 k 3 • The Machine of AS_AVGBase Data. Base (for 100 -150 users) 2 x. Opteron 2. 2 GHz, 4 GB DDR ECC Registered (up 16 GB), 2 x 36 GB System HDD SCSI, 250 GB SATA HDD (for Archive), 147 GB RAID-1 U 320 SCSI (for database), 4 x. DVD-RAM 9 GB, DVD-RW Plextor Ext, 1 Gb Ethernet (up 10 Gb Infini. Band), 19” RGB CRT 1600*1200*32 b/(75 -85)Hz, Windows NT 4. 0 & SP 1, Library MIL v 5. 0, Software AVGBase-2 k 04. • The Machine of AS_VRTBank - Temporary Data House (for 5 -10 users or for a angiography) 1 x. Opteron 2. 2 GHz, 2 GB DDR ECC Registered (up 4 GB), 36 GB System HDD SCSI, 400 GB RAID-0 SATA (up 800 GB) , 1 Gb Ethernet (up 10 Gb Infini. Band), Windows NT 4. 0 & SP 6.

Exit Summary Unprecedented quality of images for reliable diagnostics! Unprecedented speed of processing and Exit Summary Unprecedented quality of images for reliable diagnostics! Unprecedented speed of processing and visualization of medical images Medical images processing and visualization management simplicity Optimized Total Cost Ownership of AS_GSV Stations of a professional class Professional Stations 2 D Processing & Visualization Perfect Tool for Professionals!