Contents Vol 41 1 2013 г 1

Contents: Vol. 41 № 1 2013 г. 1. The Takaoka Automatic Respirator / By C. Ball, R. N. Westhorpe………………… 3 2. Frozen blood: time for outcomes / By J. Isbister………………. . 5 3. Preoperative clinics - how can they be improved? / By R. Kerridge……………. . 8 4. Frozen blood products: clinically effective and potentially ideal for remote Australia / By A. Holley, [et. al. ]……………………. . . . 10 5. Horner's syndrome in patients admitted to the paediatric intensive care unit: epidemiology, diagnosis and clinical practice / By I. Laza, [et. al. ]…………. . . ……. 20 6. The clinical role of glutamine supplementation in patients with multiple trauma: a narrative review / By R. M. Al Balushi, [et. al. ]……………………………………………………. … 24 7. Breastfeeding after anaesthesia: a review of the pharmacological impact on children / By T. C. Chu, J. Mc. Callum, M. F. Yii……………………………………………………. . … 35 8. Comparison of physiological responses to spontaneous breathing trials with a T-tube and low-level pressure support / By S. Y. Ruan, [et. al. ]……………………………………………. … 41 9. A prospective randomised comparison of the LMA Pro. Seal™ versus endotracheal tube on the severity of postoperative pain following gynaecological laparoscopy / By J. D. Griffiths, [et. al. ]……………… 46 10. The analgesic effect of intrathecal dexmedetomidine or clonidine, with bupivacaine, in trauma patients undergoing lower limb surgery: a randomised, double-blind study / By S. L. Solanki, [et. al. ]………… 51 11. The relationship between patient data and pooled clinical management decisions / By G. I. Ludbrook, [et. al. ]……………………………………………………………… 57 12. Oseltamivir pharmacokinetics in critically ill adults receiving extracorporeal membrane oxygenation support / By H. Mulla H, [et. al. ]……………………………………………… 66 13. Australian paediatric hyperbaric oxygen therapy 1998 -2011 / By G. Frawley, [et. al]……………. . 74 14. Epidural anaesthesia with goal-directed administration of ropivacaine improves haemodynamic stability when combined with general anaesthesia in elderly patients undergoing major abdominal surgery / By Q. H. Zhou, W. P. Xiao, X. Yun …………………………………………………. . 82

15. The anaesthetic pre-admission clinic is effective in minimising surgical cancellation rates / By A. Emanuel, R. Macpherseon ………………………………………………………. . … 90 16. Financial and environmental costs of manual versus automated control of end-tidal gas concentrations / By S. Tay, [et. al]…………………………………………………………. . 95 17. A survey of aseptic precautions and needle type for paediatric caudal block in Australia and New Zealand / By C. J. Fahy, D. A. Costi, A. M. Cyna…………………………………………. . . 102 18. Early tracheal stenosis causing extubation failure and prolonged ventilator dependency / By L. Dalar, [et. al]………………………………………………………………. . . 108 19. Spinal pethidine for elective caesarean section / By R. M. Vassiliadis; P. G. Taylor………………. 113 20. Systemic mastocytosis presenting as intraoperative anaphylaxis with atypical features: a report of two cases / By D. E. Bridgman, [et. al]………………………………………………… 116 21. Correspondence…………………………………………………… 122 22. Book Reviews……………………………………………………. . . 135

Contents: Vol. 41 № 2 2013 г. 1. Insufflation anaesthesia and the Kelly-Mott machine / By C. Ball, R. N. Westhorpe………………………………………… 147 2. Hypercapnia: keeping therapy and diagnosis distinct / By M. J. Tobin…………. 149 3. Errors in the interpretation of 'no statistically significant difference' / By N. M. Gibbs…………………………………………. . 151 4. The intralipid genie is out of the bottle-spin and wishful thinking / By N. A. Buckley, A. H. Dawson…………………………………. . 154 5. Carbon dioxide clearance in critical care / By R. Tiruvoipati, [et. al]………………………. . 157 6. The patient inflating valve in anaesthesia and resuscitation breathing systems / By P. M. Fenton, G. Bell…. 163 7. Is suppression of apoptosis a new therapeutic target in sepsis? / By M. Harjai……………. . . . 175 8. Interventional neuroradiological procedures-a review for anaesthetists / By M. W. Hayman, M. S. Paleologos, P. C. Kam…………………………………………………………. . . 184 9. Sevoflurane alone and propofol with or without remifentanil for electroconvulsive therapy-a randomised, crossover study / By Z. Begeç, [et. al]…………………………………………. . 202 10. Effectiveness of a patient blood management data system in monitoring blood use in Western Australia / By S. A. Mukhtar, [et. al]…………………………………………………. . 207 11. Tracheostomy in the critically ill: the myth of dead space / By M. J. Joseph, [et. al]……………… 216 12. Pain relief and opioid requirements in the first 24 hours after surgery in patients taking buprenorphine and methadone opioid substitution therapy / By P. E. Macintyre, [et. al]………………………… 222 13. Eosinopenia as a predictor of unexpected re-admission and mortality after intensive care unit discharge / By B. Yip, K. M. Ho…………………. . . . . . . . . 231 14. Simulation training for rare medications in the intensive care unit-a study with bivalirudin / By T. Edrich, G. Frendl…………………………………………………………. . . 242

16. Spontaneous coronary artery dissection in pregnancy requiring emergency caesarean delivery followed by coronary artery bypass grafting / By L. Weinberg, [et. al]……………………………… 251 17. Differentiating athlete's heart from inherited cardiac pathology: the challenge of repolarisation abnormalities presenting during anaesthesia / By P. Dzendrowskyj, B. Hamilton, M. G. Wilson…………………. . 256 18. The use of contrast-enhanced ultrasonography in the ICU for exclusion of active bleeding and detection of regional perfusion impairment in a transplanted liver / By I. Göcze, [et. al]……………………. . 261 19. Acute respiratory distress syndrome with refractory hypoxaemia and severe septic shock caused by melioidosis: successful treatment with veno-venous extracorporeal membrane oxygenation / By P. J. van der Geest, [et. al]………………………………………………………. . … 262 20. Management of near fatal mixed tricyclic antidepressant and selective serotonin reuptake inhibitor overdose with Intralipid 20% emulsion / By A. Nair, F. K. Paul, M. Protopapas…………………. . 264 21. An unusual cause of respiratory distress in the neurosurgical intensive care unit / By S. Banik, [et. al]…. . . 265 22. Klebsiella oxytoca outbreak in an intensive care unit: a probable link to common insulin vial use / By B. Mete, [et. al]…………………………………………………………. . 266 23. An alternative method of transverse in-plane ultrasound-guided thoracic paravertebral blockade / By C. O. Tan, [et. al]………………………………………………………… 268 24. Controversies in stress ulcer bleeding prophylaxis arise from differences in the quality of the evidence / By A. N. Barkun, M. Bardou, M. Martel…………………………………………… 269 25. General anaesthesia in a recent heart transplant recipient for endovascular aortic aneurysm repair / By C. Batistaki, [et. al]……………………………………………………… 270 26. Documentation of regional anaesthesia for caesarean delivery / By M. Miu, M. J. Paech………………. 271 27. Tetanus in a patient with a maggot-colonised head tumor / By H. Fox, F. H. Seeger……………. . . 272 28. The use of videolaryngoscopy for the emergency removal of hypopharyngeal foreign bodies / By R. M. Corso, [et. al]…………………………………………………………. 273 29. Editor's note: Notice of retraction / By N. Gibbs………………………………… 275

Contents: Vol. 41 № 3 2013 г. 1. Insufflation anaesthesia and the Shipway apparatus / By R. N. Westhorpe, C. Ball……………………………………………. . 287 2. Postgraduate specialty training in private institutions / By R. Hislop………… 289 3. Intensive care sedation, trends and habits / By Y. Shehabi…………… 291 4. National anaesthesia mortality reporting in Australia from 1985 -2008 / By N. M. Gibbs……………………………………………. 294 5. Primary anaesthetic deaths in Western Australia from 1985 -2008: causation and preventability / By N. M. Gibbs, P. Rodoreda……………………………………………………… 302 6. The association between sedation practices and duration of mechanical ventilation in intensive care / By A. Jarman, [et. al]………………………………………………………. . … 311 7. The prevalence of anaemia, hypochromia and microcytosis in preoperative cardiac surgical patients / By O. David, [et. al]………………………………………………………… 316 8. Can the presence of significant coagulopathy be useful to exclude symptomatic acute pulmonary embolism? / By K. M. Ho, J. A. Tan……………………………………. . . 323 9. Effects of dexmedetomidine infusion on laryngeal mask airway removal and postoperative recovery in children anaesthetised with sevoflurane / By L. He, [et. al]……………………. . . ……………… 328 10. How do anaesthetists in New Zealand disseminate critical airway information? / By P. Baker, [et. al]…. … 334 11. Validating a process-of-care checklist for intensive care units / By K. M. Conroy, D. Elliott, A. R. Burrell…. . . 342 12. Bench performance of ventilators during simulated paediatric ventilation / By M. A. Park, R. C. Freebairn, C. D. Gomersall………………………………………………………. . 349 13. Has the middle-level anaesthesia manpower training program of the West African College of Surgeons fulfilled its objectives? / By C. O. Bode, [et. al]……………………………………. . … 359 14. Outcomes in critical care delivery at Jimma University Specialised Hospital, Ethiopia / By Z. A. Smith, Y. Ayele P. Mc. Donald……………………………………………………. . . 363

15. A survey of patient understanding and expectations of sedation/anaesthesia for colonoscopy / By N. Chatman, [et. al]……………………………………………………… 369 16. A survey of the management of neuromuscular blockade monitoring in Australia and New Zealand / By S. Phillips, P. A. Stewart, A. B. Bilgin…………. . . . . . . . 374 17. Donation after cardiac death in non-survivable burns / By N. J. Widdicombe, [et. al]……………. . … 380 18. Post-cardiac surgery thrombotic thrombocytopenic purpura with digital ischaemia / By L. Weinberg, [et. al]………………………………………………………………. . . 386 19. Intraoperative awake tracheal intubation using the Airway Scope™ in caesarean section / By N. Kariya, [et. al]……………………………………………………………. . . …… 390 20. Spontaneous intracranial hypotension and epidural blood patch: a report involving seven cases / By F. Ferraro, [et. al]………………………………………………………. . . … 393 21. Pre-admission processes and opportunities for improvement…………………………. . . 427 22. Failed intubation and oxygenation in a child / By D. Borshoff ………………………. . . … 428 23. Pre-admission processes and opportunities for improvement – reply / By R. Kerridge…………. … 428 24. Anaesthesia training in a private healthcare facility / By B Gelbart, B. Creati…………………. . 429 25. Failed intubation and oxygenation in a child – reply / By A. Santoro, M. Cooper……………… 429 26. Accidental intra-arterial dexmedetomidine injection in postoperative ward / By T. Ghatak, S. Samanta…. . 431 27. Dynamic ultrasound-guided, short axis, out-of-plane radial artery cannulation: the 'follow the tip' technique / By G. Goh, C. Tan, L. Weinberg……………………………………… 431 28. C-MAC™ Storz videolaryngoscope for checking vocal cord mobility following thyroidectomy / By N. Gupta, [et. al]………………………………………………………… 433 29. Sugammadex and general anaesthesia in a patient with Brugada syndrome / By A. Langley, M. Davie. . . . 434 30. Digoxin prescription in the critically ill: an unpredictably loaded problem? / By B. Mrara, J. Roberts, J. Gowardman…………………………………………………………. . . 434 31. Serum lactate dehydrogenase as an early marker of posterior reversible encephalopathy syndrome: keep your eyes open on the score of severity brain oedema / By M. Vargas, G. Servillo………………… 436 32. Delirium and Takotsubo cardiomyopathy following cardiac surgery / By L. Wang, P. Jansz, D. Baron……. 437 33. Recycled and simplified anaesthesia machines for medical missions / By I. J. Woodforth…………. 438

Vol. 41 (Suppl. 1) 2013 г. Contents: 1. Cover note / By J. Thirlwell……………………………………………. . . …… 3 2. On the origin of the first Australian Medical Journal / By R. J. Bailey………………………. 7 3. The role of Dr Isaac Aaron and the Australian Medical Journal in the dissemination of information about etherisation in the 1840 s / By J. D. Paull…………………………………………. . . 10 4. Arthur Guedel's laryngeal plug / By R. P. Haridas, T. T. Nichols…………………………. . . … 16 5. Overview of the introduction of neuromuscular monitoring to clinical anaesthesia / By T. Loughnan, A. J. Loughnan……………………………………………………………. 19

Contents: Vol. 41 № 4 2013 г. 1. The pursuit of oxygen euboxia / By M. C. Reade…………………. . 453 2. The easy option? / By B. Hennessy……………………. 456 3. High volume local infiltration analgesia compared to peripheral nerve block for hip and knee arthroplasty-what is the evidence? / By S. J. Fowler, N. Christelis………………………………………. . . … 458 4. Acute respiratory distress syndrome: current concepts and future directions / By S. Fröhlich, [et. al]…………………………………. . . 463 5. Bedside pleuroscopy in the management of undiagnosed exudative pleural effusion with acute respiratory failure / By O. Hean, [et. al]………………………………………………. . . 473 6. Epidural versus continuous transversus abdominis plane catheter technique for postoperative analgesia after abdominal surgery / By V. Rao Kadam, [et. al]…………………………………. 476 7. Is comorbid status the best predictor of one-year mortality in patients with severe sepsis and sepsis with shock? / By N. Huddle, [et. al]………………………………………………. . . 482 8. Does left ventricular tissue Doppler peak systolic velocity (Sm) reflect cardiac output in the critically ill? / By A. R. Golowenko, M. Nalos, S. J. Huang …………………………………………. 490 9. Chronic pain after caesarean delivery: an Australian cohort / [et. al]………………………. 496 10. Effect of alkalinisation of lignocaine for propofol injection pain: a prospective, randomised, double-blind study / By U. Ozgul, [et. al]………………………………………………. . . … 501 11. Current oxygenation practice in ventilated patients-an observational cohort study / By R. Panwar, [et. al]………………………………………………………………. . . 505 12. Prediction of fluid responsiveness using dynamic preload indices in patients undergoing robot-assisted surgery with pneumoperitoneum in the Trendelenburg position / By J. H. Chin, [et. al]…………… 515 13. Asialoglycoprotein receptor scintigraphy with 99 m. Tc-galactosyl human serum albumin (99 m. Tc-GSA) as an early predictor of survival in acute liver failure / By H. Tatsumi, [et. al]……………………… 523

14. Decontamination of ultrasound equipment used for peripheral ultrasound-guided regional anaesthesia / By A. Chuan, [et. al]……………………………………………………. … 529 15. Feasibility of anaesthetic provision for paediatric patients undergoing off-site intraoperative MRI-guided neurosurgery: the Singapore experience from 2009 to 2012 / By E. Lim, E. Rai, W. T. Seow…………. … 535 16. Critical airway obstruction by mediastinal masses in the intensive care unit / By A. L. Hsu………………. . 543 17. Frozen platelets for rural Australia-when, if not / By D. J. Rowe………………………. . 549 18. Hidden implications: potential antiplatelet effects of adjuvant anaesthetic agents / By R. A. Callender, [et. al]……………………………………………………………. . … 550 19. Dobutamine induced cardiogenic shock due to systolic anterior motion after mitral valve repair / By Y. B. Jeon, [et. al]………………………………………………………… 551 20. Bilateral bispectral index monitoring of a post-hemispherotomy patient with Sturge-Weber syndrome / By S. Kira, C. Arai……………………………………………………. ……… 552 21. Is it worth the weight? / By T. R. Lukins, S. I. Pett, J. Brett……………………………. . … 553 22. Inhaled iloprost plus levosimendan to decompensate right heart failure due to chronic thromboembolic pulmonary hypertension / By G. Pitsiou, [et. al]…………………………………. . . … 554 23. Perfusion index changes during emergence from anaesthesia in children / By J. J. Skowno…………………. 556

Contents: Vol. 41 № 5 2013 г. 1. The cuffed endotracheal tube / By C. Ball, R. N. Westhorpe…………………. …… 567 2. Medical co-management of high risk surgical patients / By D. A. Story, D. A. Jones…………………………………………. . . …. 569 3. Differential associations between body mass index and outcomes after elective adult cardiac surgery: a linked data cohort study / By K. M. Ho, [et. al]…………… 573 4. Type 2 diabetes mellitus, independent of insulin use, is associated with an increased risk of cardiac complications after vascular surgery / By E. J. Bakker, [et. al]……………………………………………… 584 5. A preliminary evaluation of plasma b-type natriuretic peptide as a screening test for left ventricular diastolic dysfunction in non-cardiac intensive care / By D. J. Sturgess, [et. al]………………………… 591 6. Duration of cortisol suppression following a single dose of dexamethasone in healthy volunteers: a randomised double-blind placebo-controlled trial / By M. S. Elston, [et. al]…………………. . … 596 7. Phenytoin loading doses in adult critical care patients: does current practice achieve adequate drug levels? / By M. T. Putt, [et. al]…………………………………………………… 602 8. Diagnostic potential of open lung biopsy in mechanically ventilated patients with diffuse pulmonary infiltrates of unclear aetiology / By O. E. Depuydt, [et. al]………………………………. . 610 9. Binding of local anaesthetics to the lipid emulsion Clinoleic™ 20% / By J. A. Evans, [et. al]………………… 618 10. Training for cricothyroidotomy / By K. Shetty, [et. al]…………………………. . . ……… 623 11. Approaches to learning for the ANZCA Final Examination and validation of the revised Study Process Questionnaire in specialist medical training / By J. M. Weller, [et. al]……………………. …. …… 631 12. Mental health and welfare in Australian anaesthetists / By N. J. Mc. Donnell, [et. al]……………. . … 641 13. Home blood pressure monitoring in an anaesthetic pre-admission clinic / By R. M. Franks, P. A. Macintyre ………………………………………………………………. . . 648 14. Pioneering paediatric intensive care medicine in New Zealand / By R. V. Trubuhovich…………………. . . … 655

15. Nerve sheath catheter analgesia forequarter amputation in paediatric oncology patients / By R. N. Kaddoum, [et. al]…………………………………………………. . ……… 671 16. Correspondence………………………………………………. . 678 17. Patient recollections of perioperative anaesthesia risks / By T. T. Nichols…………………… 678 18. Postgraduate specialty training in private institutions and anaesthesia training in a private healthcare facility / By M. Sinclair…………………………………………………. …. 678 19. Future trials to investigate a ward physician leadership model for the Medical Emergency Team are not logistically feasible / By W. Cheung, [et. al]……………………………………. . . …… 679 20. Airway management of an expanding soft palate haematoma in a parturient / By W. H. Teoh, S. B. Yeoh, H. K. Tan………………………………………………………………. 680 21. Absent expiratory valve missed by automated check in Dräger Primus anaesthesia workstation / By C. Sims……………………………………………………………. …. . 681 22. Vasopressor for hypothyroid patients--is phenylephrine the right choice? / By M. Mohta, [et. al]……. …… 683 23. A technique for safe endotracheal tube exchange in difficult airway patients / By R. M. Hou, [et. al]……… 684 24. Geotrichum capitatum fungaemia: an unusual pathogen in critically-ill-related infections / By W. L. Nedel, [et. al]……………………………………………………… 685 25. Unilateral plication following phrenic nerve transection and failure to wean from mechanical ventilation / By M. Salter, [et. al]……………………………………………. . ……………… 687 26. The pitfalls of anatomical abnormality in central line insertion in the ICU / By L. F. Forbes, [et. al]……. . … 689 27. Arterial injection of adrenaline causing severe hypertension during emergency gastroscopy / By A. Wu………………………………………………………………. 689

Contents: Vol. 162 № 1 2013 г. 1. Children’s Environmental Health / By A. D. Dozor, R. W. Amler……………. . 6 2. Secondhand smoke and influenza severity in children: another nail in the coffin of the tobacco industry? / By J. C. Sconce, J. Henderson…………. …. 8 3. Marching towards personalized genomic medicine / By M. R. Hegde…………. 10 4. Federal legislation and the advancement of neonatal drug studies / By J. R. Wiles; A. A. Vinks, H. Akinbi…………………………. . . 12 5. Secondhand tobacco smoke exposure and severity of influenza in hospitalized children / By K. M. Wilson, [et. al. ]…………………………… 16 6. Do stimulants reduce the risk for cigarette smoking in youth with attention-deficit hyperactivity disorder? A prospective, long-term, open-label study of extended-release methylphenidate / By P. Hammerness, [et. al. ]…. 22 7. Subtypes of preterm birth and the risk of postneonatal death / By B. D. Kamath-Rayne, [et. al. ]…………. …… 28 8. Short-term outcomes of newborns with perinatal acidemia who are not eligible for systemic hypothermia therapy / By T. L. Du. Pont, [et. al. ]……………………………………. 35 9. Does the relationship between prenatal care and birth weight vary by oral clefts? Evidence using South American and United States samples / By K. A. Nyarko, [et. al. ]……………………………. 42 10. Variations in definitions of mortality have little influence on neonatal intensive care unit performance ratings / By J. Profit, [et. al. ]………………………………………………… 50 11. Docosahexaenoic and arachidonic acid levels in extremely low birth weight infants with prolonged exposure to intravenous lipids / By D. T. Robinson, [et. al. ]………………………………. 56 12. Rectal paracetamol in newborn infants after assisted vaginal delivery may increase pain response / By E. M. Tinner, [et. al. ]……………………………………………. …… 62 13. The utility of serum hepcidin as a biomarker for late-onset neonatal sepsis / By Tai-Wel Wu, [et. al. ]. ……. . 67 14. Prediction of duration of breastfeeding among migrant and Canadian-born women: results from a multicenter study / By C. L. Dennis, [et. al. ]…………………………………………. . 72

15. Identification of physical abuse cases in hospitalized children: accuracy of International Classification of Diseases codes / By A. Hooft, [et. al. ]……………………………………… 80 16. Yield of skeletal surveys in children ≤ 18 months of age presenting with isolated skull fractures / By A. L. Laskey, [et. al. ]……………………………………………………. ……… 86 17. Preschoolers' delay of gratification predicts their body mass 30 years later / By T. R. Schlam, [et. al. ]………………………………………………………. . . 90 18. High risk blood pressure and obesity increase the risk for left ventricular hypertrophy in African-American adolescents / By B. Falkner, [et. al. ]…………………………………………. . 94 19. Glucose control predicts 2 -year change in lipid profile in youth with type 1 diabetes / By D. M. Maahs, [et. al. ]……………………………………………………………. …. 101 20. Recent decrease in the prevalence of congenital heart defects in Europe / By B. Khoshnood, [et. al. ]…. . . 108 21. Clinical characteristics and outcomes of patients with cardiac defects and congenital diaphragmatic hernia / By S. C. Menon, [et. al. ]………………………………………………. …. . . 114 22. Risk factors for and outcomes of acute kidney injury in neonates undergoing complex cardiac surgery / By C. J. Morgan, [et. al. ]……………………………………………. . . 120 23. Hyperuricemia is associated with hypertension, obesity, and albuminuria in children with chronic kidney disease / By D. G. Noone, S. D. Marks SD………………………………………. … 128 24. The utility of surgical lung biopsy in immunocompromised children / By J. A. Naiditch, K. A. Barsness, D. H. Rothstein……………………………………………………. . 133 25. Prospective randomized crossover evaluation of three anesthetic regimens for painful procedures in children with cancer / By D. L. Anghelescu, [et. al. ]…………………………………. . . 137 26. Kaposiform hemangioendothelioma: atypical features and risks of Kasabach-Merritt phenomenon in 107 referrals / By S. E. Croteau, [et. al. ]…………………………………………. . . … 142 27. Hepatitis C virus-specific cell-mediated immune responses in children born to mothers infected with hepatitis C virus / By S. S. El-Kamary, [et. al. ]……………………………………… 148 28. Pathophysiological insights derived by natural history and motor function of spinal muscular atrophy / By M. A. Farrar, [et. al. ]……………………………………………………. … 155 29. School attendance in childhood cancer survivors and their siblings / By A. E. French, [et. al. ]………………. 160 30. A family with Liddle syndrome caused by a novel missense mutation in the PY motif of the beta-subunit of the epithelial sodium channel / By L. Gao, [et. al. ]……. . . . . . … 166

31. Intermittent hyperglycemia due to autonomic nervous system dysfunction: a new feature in patients with congenital central hypoventilation syndrome / By G. Gelwane, [et. al. ]………………………. . . 171 32. Transient hypothyroidism at 3 -year follow-up among cases of congenital hypothyroidism detected by newborn screening / By S. J. Korzeniewski, [et. al. ]…………………………………. . . 177 33. Point-of-care differentiation of Kawasaki disease from other febrile illnesses / By X. B. Ling, [et. al. ]…. . … 183 34. Markers of maternal depressive symptoms in an urban pediatric clinic / By J. H. Sia, [et. al. ]……………. … 189 35. Unexplained death due to possible infectious diseases in infants-United States, 2006 / By C. A. Taylor, [et. al. ]……………………………………………………………. . …… 195 36. Whole exome sequencing reveals a novel mutation in CUL 7 in a patient with an undiagnosed growth disorder / By A. Dauber, [et. al. ]…………………………………………. . . ……… 202 37. Imatinib mesylate in the treatment of diffuse cutaneous mastocytosis / By M. A. Morren, [et. al. ]………. … 205 38. Esophageal and rectal temperatures as estimates of core temperature during therapeutic whole-body hypothermia / By S. Sarkar, [et. al. ]…………………………………… 208 39. A stitched eye in the newborn: ankyloblepharon filiforme adnatum / By M. N. Cizmeci, [et. al. ]…………… 211 40. Newborn radiographic clues for undiagnosed posterior urethral valves / By L. Barker, [et. al. ]…………. . … 213 41. Intracranial hemorrhage and a white blood cell count of almost 1 million cells/μL / By J. L. Colquitt, J. A. D'Orazio…………………………………………………………. . . 214 42. Vigabatrin-related magnetic resonance imaging abnormalities in an infant with tuberous sclerosis complex and infantile spasms / By D. T. Hsieh, E. A. Thiele…………………………………. … 215 43. Polyarteritis nodosa in a 9 -year-old boy / By V. B. Reddy, N. Schloemer……………………. 216

Content: Vol. 162 № 2 2013 г. 1. This Month in The Journal of Pediatrics……………………. . . …. 219 2. Trends in Study Designs in Pediatric Medical Education Research, 1992 -2011 / By M. Rezniik, P. O. Ozuah………………………. … 222 3. Prader-Willi syndrome and growth hormone therapy: take a deep breath and weigh the data / By B. Y. Whitman, S. E. Myers…………………. . . …… 224 4. Pediatric ischemic stroke: acute management and areas of research / By L. Titomanlio, [et al. ] …………………………………. . . 227 5. Chorioamnionitis as a risk factor for necrotizing enterocolitis: a systematic review and meta-analysis / By J. V. Been, [et al. ] ……………………………………………………. . . . 236 6. Cost of morbidities in very low birth weight infants / By T. J. Johnson, [et al. ]…………………. . . 243 7. Association of impaired linear growth and worse neurodevelopmental outcome in infants with single ventricle physiology: a report from the pediatric heart network infant single ventricle trial / By C. Ravishankar, [et al. ]…………………………………………………………. . 250 8. Lactobacillus reuteri DSM 17938 for the management of infantile colic in breastfed infants: a randomized, double-blind, placebo-controlled trial / By H. Szajewska, E. Gyrczuk, A. Horvath……………. 257 9. Longitudinal evaluation of sleep-disordered breathing in children with Prader-Willi Syndrome during 2 years of growth hormone therapy / By S. Al-Saleh, [et al. ]…………………………. 263 10. Age-dependent changes in the size of adenotonsillar tissue in childhood: implications for sleepdisordered breathing / By G. Papaioannou, [et al. ]…………………………………… 269 11. Respiratory outcome in children with scimitar syndrome / By A. Chemin, [et al. ]……………. … 275 12. Meta-analysis of the association between body mass index and health-related quality of life among children and adolescents, assessed using the pediatric quality of life inventory index / By Z. Ul-Haq, [et al. ]. 280 13. Growth during infancy and childhood, and adiposity at age 16 years: ages 2 to 7 years are pivotal / By E. T. Liem, [et al. ]………………………………………………………. …. 287

14. Comparison of anti-Xa levels in obese and non-obese pediatric patients receiving treatment doses of enoxaparin / By A. A. Richard, [et al. ]……………………………. …. 293 15. Estimated insulin sensitivity and cardiovascular disease risk factors in adolescents with and without type 1 diabetes / By B. J. Specht, [et al. ]……………………………………………. 297 16. Maternal psychological stress after prenatal diagnosis of congenital heart disease / By J. Rychik, [et al. ]. . . 302 17. The poor performance of RSR' pattern on electrocardiogram lead V 1 for detection of secundum atrial septal defects in children / By O. Schiller, [et al. ]…………………………………. . . 308 18. Geographical rural status and health outcomes in pediatric liver transplantation: an analysis of 6 years of national United Network of Organ Sharing Data / By K. T. Park, [et al. ]……………………. . . 313 19. King's College Hospital Criteria for non-acetaminophen induced acute liver failure in an international cohort of children / By V. Sundaram, [et al. ]……………………………………. . … 319 20. Clinical outcomes of neonatal onset proximal versus distal urea cycle disorders do not differ / By N. Ah Mew, [et al. ]……………………………………………………. 324 21. Diabetic ketoacidosis at diabetes onset: still an all too common threat in youth / By G. J. Klingensmith, [et al. ]……………………………………………………………. …. 330 22. Infant behaviors are predictive of functional somatic symptoms at ages 5 -7 years: results from the Copenhagen Child Cohort CCC 2000 / By C. U. Rask, [et al. ]……………………………. …. 335 23. Effects of maternal sensitivity and cognitive and linguistic stimulation on cochlear implant users' language development over four years / By A. L. Quittner, [et al. ]………………………………. …. 343 24. Randomized double-blind controlled trial of bovine lactoferrin for prevention of diarrhea in children / By T. J. Ochoa, [et al. ]………………………………………………………. . 349 25. High endogenous melatonin levels in critically ill children: a pilot study / By L. Marseglia, [et al. ]………. . 357 26. Gestational age at birth and risk of autism spectrum disorders in Alberta, Canada / By A. Leavey, [et al. ]. . 361 27. Normal imaging in patients with cerebral palsy: what does it tell us? / By R. Benini, [et al. ]………………. . 369 28. Enzyme replacement is associated with better cognitive outcomes after transplant in Hurler syndrome / By J. B. Eisengart, [et al. ]…………………………………………………. . . ……. 375 29. Sun protection counseling by pediatricians has little effect on parent and child sun protection behavior / By L. Cohen, [et al. ]…………………………………………. …. 381 30. Incidence and acute complications of asymptomatic central venous catheter-related deep venous

31. Pediatric traumatic brain injury and radiation risks: a clinical decision analysis / By K. E. Hennelly, [et al. ]……………………………………………………………. …. 392 32. Nail-fold excision for the treatment of ingrown toenail in children / By R. N. Haricharan, [et al. ]…. . ……… 398 33. Parents' perspectives on their children's health insurance: plight of the underinsured / By W. Spears…………………………………………………………. . . …. 403 34. Barriers to specialty care and specialty referral completion in the community health center setting / By K. E. Zuckerman, [et al. ]……………………………………………………. . 409 35. Patterns of catch-up growth / By C. C. de Wit, [et al. ]………………………………. . . 415 36. Maternal use of oxycodone resulting in opioid intoxication in her breastfed neonate / By N. L. Timm…. . . 421 37. Short-term femoral catheter insertion: a promising alternative to consistently allow long-term erythrocytapheresis therapy in children with sickle cell anemia / By M. Billard, [et al. ]……………. . . 423 38. Delayed diagnosis of hypothyroidism following excision of a thyroglossal duct cyst / By J. S. Lilley, J. P. Lomenick…………………………………………………………… 427 39. Femoral fracture as a rare presentation of prepubertal graves disease / By S. Cheruvu, B. K. Alverson, J. B. Quintos…………………………………………………… 429 40. Not all Twitching is Epileptic! Hand Myoclonus in a Boy with Spinal Cord Tumor / By N. M. Allen, M. M. Moran, M. D. King……………………………………………………. . 431 41. Vaginal bleeding leading to incidental diagnosis of ovarian torsion in an infant with 21 hydroxylase deficiency congenital adrenal hyperplasia / By A. Choudhary, [et al. ]………………………. . … 432 42. Meconium peritonitis with intestinal atresia mimicking huge tumor in a preterm neonate / By C. H. Lien, [et al. ]…………………………………………………………. 433 43. A classic case of a plastic bowing deformation / By D. Marikar, J. Akhtar…………………… 434 44. Invasive giant prolactinoma presenting as a nasal polyp / By B. Sunil, [et al. ]………………. . . 435

Content: Vol. 162 № 3 2013 г. 1. Training tomorrow's medical education leaders: creating a general pediatric master educator fellowship / By M. Klein, [et al. ]………………. . . 440 2. Assisting the onset of breathing-can neonatologists and babies work better together? / By K. Bohlin………………………………. …. . 442 3. Why do former preterm infants wheeze? / By R. J. Martin, Y. S. Prakash, A. M. Hibbs…………………………………………. . . 443 4. Critical congenital heart disease screening using pulse oximetry / By L. H. Frank, [et al. ]… ……………………………………. 445 5. Screening in pediatrics-more questions than answers? / By J. R. Kaltman, K. M. Burns, G. D. Pearson………… 454 6. Evaluating manual inflations and breathing during mask ventilation in preterm infants at birth / By K. Schilleman, [et al. ]……………………………………………. . 457 7. Respiratory function in healthy late preterm infants delivered at 33 -36 weeks of gestation / By C. Mc. Evoy, [et al. ]………………………………………………………………. 464 8. Patterns of altered neurobehavior in preterm infants within the neonatal intensive care unit / By R. G. Pineda, [et al. ]…………………………………………………………… 470 9. Predischarge screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy / By Bhutani, [et al. ]…………………………………………………………………………………………………………. . . 477 10. Maternal life stress events in pregnancy link to children's school achievement at age 10 years / By J. Li, [et al. ]……………………………………………………………. . 483 11. Massage improves growth quality by decreasing body fat deposition in male preterm infants / By L. J. Moyer-Mileur, [et al. ]……………………………………………………. . 490 12. Increasing prevalence of nonalcoholic fatty liver disease among United States adolescents, 1988 -1994 to 2007 -2010 / By J. A. Welsh, S. Karpen, M. B. Vos……………………………………. 496

13. Multicenter study on season of birth and celiac disease: evidence for a new theoretical model of pathogenesis / By P. Tanpowpong, [et al. ]………………………………………. …. . 501 14. Abdominal pain and functional gastrointestinal disorders in children with celiac disease / By M. Saps, [et al. ]……………………………………………………………. …. … 505 15. Association between early childhood otitis media and pediatric inflammatory bowel disease: an exploratory population-based analysis / By S. Y. Shaw, J. F. Blanchard, C. N. Bernstein………………. . . 510 16. Treatment of severe acute malnutrition in infants aged < 6 months in Niger / By S. B. Vygen, [et al. ]…… 515 17. Effects of immediate telephone follow-up with providers on sweat chloride test timing after cystic fibrosis newborn screening identifies a single mutation / By A. La Pean, [et al. ]…………………. . . …… 522 18. Better nutritional status in early childhood is associated with improved clinical outcomes and survival in patients with cystic fibrosis / By E. H. Yen, H. Quinton, D. Borowitz………………………. . … 530 19. Predictors for asthma at age 7 years for low-income children enrolled in the Childhood Asthma Prevention Study / By G. P. Tamesis, [et al. ]……………………………………………… 536 20. Exercise improves behavioral, neurocognitive, and scholastic performance in children with attentiondeficit/hyperactivity disorder / By M. B. Pontifex, [et al. ]……………………………… 543 21. Methods of standing from supine and percentiles for time to stand to run 10 meters in young children / By J. Ng, [et al. ]……………………………………………… 552 22. Parent and child self-reports of dietary behaviors, physical activity, and screen time / By J. E. Thorn, [et al. ]………………………………………………………………. 557 23. Random luteinizing hormone often remains pubertal in children treated with the histrelin implant for central precocious puberty / By K. A. Lewis, E. A. Eugster……………………………. . …. 562 24. Gastroesophageal reflux, esophageal function, gastric emptying, and the relationship to dysphagia before and after antireflux surgery in children / By C. Loots, [et al. ]…………………………… 566 25. Gender differences in partner influences and barriers to condom use among heterosexual adolescents attending a public sexually transmitted infection clinic in Singapore / By M. L. Wong, [et al. ]………………. … 574 26. Maternal residential atrazine exposure and risk for choanal atresia and stenosis in offspring / By A. J. Agopian, [et al. ]……………………………………………………… 581 27. Continuous renal replacement therapy for children ≤ 10 kg: a report from the prospective pediatric continuous renal replacement therapy registry / By D. J. Askenazi, [et al. ]……………………. . 587

28. Congenital cytomegalovirus is the second most frequent cause of bilateral hearing loss in young French children / By V. Avettand-Fenoël, [et al. ]………………………………………. . . 593 29. Early life socioeconomic indicators and risk of type 1 diabetes n children and young adults / By G. Bruno, [et al. ]…………………………………………………………. …. . 600 30. Living on higher ground reduces child neurodevelopment-evidence from South America / By G. L. Wehby…………………………………………………………… 606 31. Homozygous SALL 1 mutation causes a novel multiple congenital anomaly-mental retardation syndrome / By J. Vodopiutz, [et al. ]…………………………………………………. . 612 32. Disparities in psychiatric emergency department visits among youth in Hawai'i, 2000 -2010 / By C. R. Matsu, [et al. ]……………………………………………………………. . . 618 33. Determinants of health care use in a population-based leukodystrophy cohort / By C. Nelson, [et al. ]…. . . 624 34. Validation of search filters for identifying pediatric studies in Pub. Med / By E. Leclercq, [et al. ]…………. . . 629 35. Clinical presentation of cervical ribs in the pediatric population / By K. H. Chan, [et al. ]…………. 635 36. Incidence and characteristics of pseudoprecocious puberty because of severe primary hypothyroidism / By S. M. Cabrera, L. A. Di. Meglio, E. A. Eugster………………………………………. . 637 37. Intravenous fluids versus gastric-tube feeding in hospitalized infants with viral bronchiolitis: a randomized, prospective pilot study / By A. Kugelman, [et al. ]……………………………. 640 38. Vesiculopustular eruption in neonate with trisomy 21 and transient myeloproliferative disorder / By N. Iwashit, [et al. ]……………………………………………………. . …… 643 39. Air trail of a transilluminant scrotum / By B. Adhisivam, [et al. ]…………………… 645 40. Coarctation of the aorta in late adolescence / By D. J. Hall, [et al. ]……………………. . …… 646 41. Moth-eaten appearance of tubulointerstitial nephritis and uveitis syndrome on (99 m)technetium dimercaptosuccinic acid scintigraphy / By M. Shimizu, [et al. ]………………………. ……… 647 42. Alexander disease / By D. I. Zafeiriou, P. Dragoumi, E. Vargiami………………………. . … 648

Global Neonatal Consensus Symposium: Feeding the Preterm Infant Content: Vol. 162. № 3 (Suppl. 1. ) 2013 г. 1. Introduction to the symposium on nutrition of the preterm infant / By R. Uauy, C. L. Berseth………………………………………. . . …. … 1 2. Growth curves: how to best measure growth of the preterm infant / By J. Bhatia…………………………………………. . …. 2 3. Feeding preterm infants today for later metabolic and cardiovascular outcomes / By A. Lapillonne, I. J. Griffin……………………………. . 7 4. Human milk and the nutritional needs of preterm infants / By D. I. Tudehope. . . 17 5. Vitamin D, vitamin A, maternal-perinatal considerations: old concepts, new insights, new questions / By T. Murguía-Peniche………………………………………………………. 26 6. Evaluation of adequacy of protein and energy / By J. Bhatia, [et al. ]………………………. … 31 7. Lipid needs of preterm infants: updated recommendations / By А. Lapillonne, [et al. ]…………. …… 37 8. Selected macro/micronutrient needs of the routine preterm infant / By J. Bhatia, [et al. ]…………………. …… 48 9. Intestinal mucosal defense system, Part 1. Consensus recommendations for immunonutrients / By J. Neu, [et al. ]……………………………………………………………… 56 10. Intestinal mucosal defense system, Part 2. Probiotics and prebiotics / By Т. Murguía-Peniche, [et al. ]……… 64 11. Nutritional needs of the micropreterm infant / By D. Tudehope, [et al. ]…………………. …… 72 12. Nutritional requirements and feeding recommendations for small for gestational age infants / By D. Tudehope, [et al. ]………………………………………………………. … 81 13. Nutritional recommendations for the late-preterm infant and the preterm infant after hospital discharge / By А. Lapillonne, [et al. ]…………………………………………………. … 90 14. Feeding the preterm infant: opportunities and challenges of bringing science to the bedside / By J. Neu, [et al. ]……………………………………………………………. . …… 101 15. Nutritional management of the low birth weight/preterm infant in community settings: a perspective from the developing world / By А. Imdad, Z. A. Bhutta…………………………………. . 107 16. Symposium summary: looking back and looking forward / By C. L. Berseth, R. Uauy…………. . … 115

Content: Vol. 162 № 4 2013 г. 1. This Month in The Journal of Pediatrics………………. . …. 661 2. Innovation in physician recruitment & wellness: a pilot orientation program / By V. G. Kirk [et al. ]…………………………………… 664 3. "An Editor's Editor"-Joseph Morris Garfunkel, MD (January 1, 1926 - January 16, 2013) / By W. F. Balistreri………………………. . . …………. 666 4. Postnatal steroids in the preterm infant-the good, the ugly, and the unknown / By T. E. Inder, M. Benders…………………. 667 5. What if you could see lung inflation in real time? / By М. Keszler………………………. . … 670 6. The importance of understanding the impact of children's food marketing on the brain / By A. N. Gearhardt, K. D. Brownell………………………………………………………… 672 7. Anti-N-methyl-D-aspartate receptor encephalitis: what's in a name? / By C. J. Campen, F. P. Gisher…………. . 673 8. Pitfalls of drug development: lessons learned from trials of denufosol in cystic fibrosis / By R. B. Moss…. 676 9. Administrative data: expanding the infrastructure for pediatric research / By L. V. Ambroggio, S. S. Shah…… 681 10. Pilot randomized trial of hydrocortisone in ventilator-dependent extremely preterm infants: effects on regional brain volumes / By N. A. Parikh, [et al. ]……………………………………. . . 685 11. Effect of nasal continuous and biphasic positive airway pressure on lung volume in preterm infants / By М. Miedema, [et al. ]……………………………………………………. . … 691 12. Cerebral oxygenation, extraction, and autoregulation in very preterm infants who develop periintraventricular hemorrhage / By Т. Alderliesten, [et al. ]………………………… 698 13. Randomized trial of early developmental intervention on outcomes in children after birth asphyxia in developing countries / By W. A. Carlo, [et al. ]……………………………………… 705 14. Prenatal exposure to nicotine and impaired reading performance / By: К. Cho, [et al. ]……………. 713 15. Impaired language abilities and white matter abnormalities in children born very preterm and/or very low birth weight / By N. Reidy, [et al. ]…………………………………………… 719

16. Acute kidney injury in asphyxiated newborns treated with therapeutic hypothermia / By D. T. Selewski, [et al. ]………………………………………………………. . …………… 725 17. Social determinants of health on glycemic control in pediatric type 1 diabetes / By C. S. Zuijdwijk, М. Cuerden, F. H. Mahmud………………………………………………. . . ……. 730 18. Body mass index at the time of diagnosis of autoimmune type 1 diabetes in children / By B. M. Kaminski, [et al. ]…………………………………………………………. . ………… 736 19. Impact of gestational diabetes mellitus on pubertal changes in adiposity and metabolic profiles in Latino offspring / By J. N. Davis, [et al. ]…………………………………………. … 741 20. The hypertriglyceridemic waist, waist-to-height ratio, and cardiometabolic risk / By D. P. Bailey, [et al. ]… 746 21. Childcare and overweight or obesity over 10 years of follow-up / By M. C. Geoffroy, [et al. ]……………. …… 753 22. Brain responses to food logos in obese and healthy weight children / By A. S. Bruce, [et al. ]…………. …. … 759 23. Nocturnal sleep measured by actigraphy in children with Prader-Willi syndrome / By S. Gibbs, Е. Wiltshire, D. Elder……………………………………………………. . 765 24. Prognostic values of multichannel intraluminal impedance and p. H monitoring in newborns with symptoms of gastroesophageal reflux disease / By F. Cresi, [et al. ]………………………. …… 770 25. 0. 5 mg/kg versus 1 mg/kg of intravenous omeprazole for the prophylaxis of gastrointestinal bleeding in critically ill children: a randomized study / By M. J. Solana, [et al. ]………………………. . … 776 26. Red flags in children with chronic abdominal pain and Crohn's disease-a single center experience / By К. El-Chammas, [et al. ]…………………………………………………. …… 783 27. Acute necrotizing pancreatitis in children / By А. Raizner, [et al. ]……………………. …… 788 28. High rates of resolution of cholestasis in parenteral nutrition-associated liver disease with fish oil-based lipid emulsion monotherapy / By M. H. Premkumar, [et al. ]……………………………. . . … 793 29. Effects of рropranolol and exercise training in children with severe burns / By L. J. Porro, [et al. ]………… 799 30. Klein line on the anteroposterior radiograph is not a sensitive diagnostic radiologic test for slipped capital femoral epiphysis / By G. J. Pinkowsky, W. L. Hennrikus…………………………. 804 31. Evolution of pancreatic function during the first year in infants with cystic fibrosis / By B. P. O'Sullivan, [et al. ]…………………………………………………………. ……… 808 32. Exercise-induced bronchoconstriction in school-aged children who had chronic lung disease in infancy / By S. Joshi, [et al. ]……………………………………………………. … 813

33. Distinguishing deficiencies in the steroidogenic acute regulatory protein and the cholesterol side chain cleavage enzyme causing neonatal adrenal failure / By Z. S. Gucev, [et al. ]…………………… 819 34. Vitamin D status in neonates undergoing cardiac operations: relationship to cardiopulmonary bypass and association with outcomes / By E. M. Graham, [et al. ]………………………………. . …… 823 35. Lone atrial fibrillation in the young - perhaps not so "lone"? / By S. R. Ceresnak, [et al. ]…………………. …. 827 36. Use of antibiotics during pregnancy increases the risk of asthma in early childhood / By L. G. Stensballe, [et al. ]……………………………………………………………. … 832 37. The role of radiation therapy in pediatric mucoepidermoid carcinomas of the salivary glands / By J. Thariat, [et al. ]…………………………………………………………… 839 38. Hypoplastic anemia in cartilage-hair hypoplasia-balancing between iron overload and chelation / By М. Taskinen, [et al. ]……………………………………………………… 844 39. Pediatric anti-N-methyl-D-aspartate receptor encephalitis-clinical analysis and novel findings in a series of 20 patients / By Т. Armangue, [et al. ]……………………………………. . . ………… 850 40. A single-blinded randomized clinical trial comparing polymyxin B-trimethoprim and moxifloxacin for treatment of acute conjunctivitis in children / By L. Williams, [et al. ]………………………. . … 857 41. Alarming signs in the Manchester triage system: a tool to identify febrile children at risk of hospitalization / By van Y. Ierland, [et al. ]………………………………………………. …. 862 42. Smarter lunchrooms can address new school lunchroom guidelines and childhood obesity / By A. S. Hanks, D. R. Just, В. Wansink……………………………………………. . …… 867 42. Urinary free bisphenol A and bisphenol A-glucuronide concentrations in newborns / By R. M. Nachman, [et al. ]……………………………………………………………. … 870 43. State-to-state variability in Title V coverage for children with diabetes / By P. M. Wolfgram, [et al. ]……. . … 873 44. A scalp disorder: dermatoscopy as a useful diagnostic tool / By J. Orgaz-Molina, [et al. ]………………. . . …… 876 45. A 6 -year-old girl with a lingual ulcer / By А. Raaijmakers, J. Toelen……………………. . . ……. 878 46. A diagnostic dilemma: inflammatory linear verrucous epidermal nevus versus linear psoriasis / By A. Z. Akelma, [et al. ]………………………………………………………. . … 879 47. Infantile tullio phenomenon / By Y. Kakisaka, [et al. ]……………………………… 880 48. Uncommon cause of large paravertebral calcification in a child / By J. P. Llano, Е. Beaufils, М. Nicolino…. . 881 49. Congenital primarily ulcerated hemangioma mimicking cleft lip / By I. Neri, [et al. ]…………. . . … 882

Content: Vol. 162 № 5 2013 г. 1. This Month in The Journal of Pediatrics……………. . 885 2. Closing the gap: a needs assessment of medical students and handoff training / By J. K. O'Toole, [et al. ]………………………………. . . 887 3. Preeclampsia and prematurity as precursors to adolescent obesity / By R. A. Simmons………………………………………. . … 889 4. A new risk factor for type 2 diabetes may offer a teachable moment for prevention / By D. Styne……………………………. …… 890 5. Possible continuous positive airway pressure treatment of children with pneumonia / By W. Keenan……. . 892 6. Is melatonin synthesis a new biomarker for the pathogenesis and treatment of phenylketonuria? / By S. Cederbaum, H. L. Levy…………………………………………………. . . …… 893 7. Life with spina bifida: the role of quality of life in decision-making / By J. M. Freeman…………… 894 8. Uric acid and the origins of hypertension / By D. I. Feig, [et al. ]………………………… 896 9. The disappearance of diseases, conditions, and disorders of childhood / By R. W. Chesney…………………. . 903 10. Birth weight and carotid artery intima-media thickness / By J. Dratva, [et al. ]……………. . . ………. 906 11. Adiposity in adolescent offspring born prematurely to mothers with preeclampsia / By L. Washburn, [et al. ]……………………………………………………………. . …… 912 12. Higher maternal body mass index is associated with an increased risk for later type 2 diabetes in offspring / By М. Juonala, [et al. ]…………………………………………………. . 918 13. Indices of insulin secretion during a liquid mixed-meal test in obese youth with diabetes / By F. Bacha, [et al. ]………………………………………………………………. . 924 14. Intrahepatic fat is increased in the neonatal offspring of obese women with gestational diabetes / By D. E. Brumbaugh, [et al. ]…………………………………………………. . 930 15. Using the androgen excess-PCOS society criteria to diagnose polycystic ovary syndrome and the risk of metabolic syndrome in adolescents / By A. H. Roe, [et al. ]…………………………. …. . 937

16. Early sepsis does not increase the risk of late sepsis in very low birth weight neonates / By J. L. Wynn, [et al. ]…………………………………………………. . 942 17. A randomized controlled trial to compare heated humidified high-flow nasal cannulae with nasal continuous positive airway pressure postextubation in premature infants / By C. L. Collins, [et al. ]………. . 949 18. Newborn screening: a national snapshot with implications for emergency preparedness / By Р. Floyd. Browning, [et al. ]………………. . ……………………………………. . 955 19. p. H effects on cardiac function and systemic vascular resistance in preterm infants / By S. Noori, T. W. Wu, I. Seri……………………………………………………………. …… 958 20. Life-threatening tumors of the heart in fetal and postnatal age / By А. Pucci, [et al. ]……………. 964 21. Prenatal tobacco exposure, biomarkers for tobacco in meconium, and neonatal growth outcomes / By S. K. Himes, [et al. ]………………. . …. ……………………………………. . . 970 22. Esophageal mechanosensitive mechanisms are impaired in neonates with hypoxic-ischemic encephalopathy / By C. D. Hill, S. R. Jadcherla……………………………………… 976 23. Diagnostic accuracy of tests in pediatric gastroesophageal reflux disease / By R. J. van der Pol, [et al. ]……. 983 24. A randomized clinical trial evaluating nasal continuous positive airway pressure for acute respiratory distress in a developing country / By P. T. Wilson, [et al. ]………………………………. . . 988 25. Health outcomes among youths and adults with spina bifida / By N. L. Young, [et al. ]……………. 993 26. Large neutral amino acid supplementation increases melatonin synthesis in phenylketonuria: a new biomarker / By S. Yano, К. Moseley, С. Azen……………………………………. . … 999 27. A genome-wide methylation study of severe vitamin D deficiency in African American adolescents / By Н. Zhu, [et al. ]……………. . …………………………………………… 1004 28. Evaluation of the liver injury unit scoring system to predict survival in a multinational study of pediatric acute liver failure / By B. R. Lu Zhang, [et al. ]……………………………………. . … 1010 29. Nanofiltered C 1 -esterase inhibitor for the acute management and prevention of hereditary angioedema attacks due to C 1 -inhibitor deficiency in children / By W. Lumry, [et al. ]…………………… 1017 30. Functional nonretentive fecal incontinence: do enemas help? / By R. Burgers, [et al. ]…………………. …… 1023 31. Associating child sexual abuse with child victimization in China / By K. L. Chan, Е. Yan, D. A. Brownridge, Р. Ip…………………………………………………………. . ………… 1028 32. Infant video viewing and salivary cortisol responses: a randomized experiment / By D. A. Christakis, [et al. ]……………………………………………………………… 1035

33. Arteriopathy, D-dimer, and risk of poor neurologic outcome in childhood-onset arterial ischemic stroke / By N. A. Goldenberg, [et al. ]………………………………………………… 1041 34. The neuropsychological and academic substrate of new/recent-onset epilepsies / By D. C. Jackson, [et al. ]……………………………………………………………… 1047 35. Responses of obese and lean girls exercising under heat and thermoneutral conditions / By G. T. Leites, [et al. ]……………………………………………………………… 1054 36. He fell from Dad's arms: subdural hemorrhages in an infant / By A. S. Botash………………. 1061 37. Effects from birth brachial plexus injury and postural control / By Е. Ridgway, [et al. ]…………………. . … 1065 38. Black race is not protective against hazardous bilirubin levels / By А. С. Wickremasinghe, M. W. Kuzniewicz, T. B. Newman……………………………………………………. 1068 39. Mongolian spots are not always a benign sign / By В. А. Hackbart, [et al. ]……………. . …………… 1070 40. A curious rash / By I. Rabach, [et al. ]……………………. . … 1071 41. Gastrocolic fistula: a cause of short stature and delayed puberty in an adolescent with chronic diarrhea / By W. Haller, М. Zacharin, A. G. Catto-Smith………. …………………………………. ……. . 1073 42. Generalized arterial calcification of infancy / By G. Karthikeyan……………………. …. . 1074 43. Meckel diverticulum in a premature infant: too tiny but still perforates / By Т. Smolkin, [et al. ]………. . … 1075 44. Congenital extrahepatic portocaval shunt: growth in vain / By Р. Velayutham, А. Dev, A. Arora…………. . . 1076

Content: Vol. 39 № 1 2013 г. 1. Effect of occlusal reduction on postoperative pain in teeth with irreversible pulpitis and mild tenderness to percussion / By М. Parirokh, [et al. ]……………. …. … 1 2. Efficacy of articaine versus lidocaine in block and infiltration anesthesia administered in teeth with irreversible pulpitis: a prospective, randomized, doubleblind study / By Н. Ashraf, [et al. ]…………………………. . …. …… 6 3. Comparison of fracture resistance between cast posts and fiber posts: a metaanalysis of literature / By L. Zhou, Q. Wang…………………. …. … 11 4. Pixel intensity and fractal dimension of periapical lesions visually indiscernible in radiographs / By Е. Soğur, [et al. ]………………………………………………………. . . …… 16 5. Treatment outcome of mineral trioxide aggregate in open apex teeth / By J. Mente, [et al. ]…………………. … 20 6. Occurrence of cervical invasive root resorption in first and second molar teeth of orthodontic patients eight years after bracket removal / By А. Thönen, [et al. ]…………………………………… 27 7. Isolation and characterization of dental pulp stem cells from a patient with Papillon-Lefèvre syndrome / By P. N. Taşlı, [et al. ]……………………………………………………… 31 8. Streptococcus gordonii collagen-binding domain protein Cbd. A may enhance bacterial survival in instrumented root canals ex vivo / By P. J. Moses, [et al. ]………………………………. . 39 9. Identification of the genes involved in the biofilm-like structures on actinomyces oris K 20, a clinical isolate from an apical lesion / By С. Mashimo, [et al. ]……………………………………. . 44 10. Development of an ex vivo coculture system to model pulpal infection by Streptococcus anginosus group bacteria / By J. L. Roberts, [et al. ]…………………………………………. ……… 49 11. Camphorquinone inhibits odontogenic differentiation of dental pulp cells and triggers release of inflammatory cytokines / By R. H. Kim, [et al. ]………………………………. ……. . . ……… 57 12. Regulation of matrix metalloproteinases, tissue inhibitor of matrix metalloproteinase-1, and extracellular metalloproteinase inducer by interleukin-17 in human periodontal ligament fibroblasts / By Y. Wu, [et al. ]… 62 13. Calcium ions released from mineral trioxide aggregate convert the differentiation pathway of C 2 C 12 cells into osteoblast lineage / By S. Matsumoto, [et al. ]…………………………………. . . … 68

14. Combined effects of simvastatin and enamel matrix derivative on odontoblastic differentiation of human dental pulp cells / By L. Karanxha, [et al. ]………………………………………… 76 15. Evidence supporting a protective role for th 9 and th 22 cytokines in human and experimental periapical lesions / By А. М. Aranha, [et al. ]……………………………………………… 83 16. Detection of dentinal microcracks using infrared thermography / By М. Matsushita-Tokugawa, [et al. ]…. … 88 17. Comparison of the self-adjusting file with rotary and hand instrumentation in long-oval-shaped root canals / By J. E. Ruckman, [et al. ]……………………………………………. … 92 18. Comparative evaluation of fracture resistance under static and fatigue loading of endodontically treated teeth restored with carbon fiber posts, glass fiber posts, and an experimental dentin post system: an in vitro study / By К. Ambica, [et al. ]………………………………………………… 96 19. Torsion and bending properties of shape memory and superelastic nickel-titanium rotary instruments / By Е. Ninan, D. W. Berzins…………………………………………………. . . …. 101 20. Cold plasma therapy of a tooth root canal infected with enterococcus faecalis biofilms in vitro / By J. Pan, [et al. ]…………………………………………………………. …… 105 21. The effect of various mixing and placement techniques on the compressive strength of mineral trioxide aggregate / By F. B. Basturk, [et al. ]…………………………………………. . . …… 111 22. Antimicrobial activity of triantibiotic paste, 2% chlorhexidine gel, and calcium hydroxide on an intraoralinfected dentin biofilm model / By R. Ordinola-Zapata, [et al. ]………………………. ……… 115 23. Effect of apical size and taper on volume of irrigant delivered at working length with apical negative pressure at different root curvatures / By С. de Gregorio, [et al. ]………………………. . . …… 119 24. Time required to remove guttacore, thermafil plus, and thermoplasticized gutta-percha from moderately curved root canals with protaper files / By R. T. Beasley, [et al. ]…………………………… 125 25. Incidence of apical root cracks and apical dentinal detachments after canal preparation with hand rotary files at different instrumentation lengths / By R. Liu, [et al. ]………………………… 129 26. Influence of combined cyclic fatigue and torsional stress on the fracture point of nickel-titanium rotary instruments / By F. C. Setzer, C. P. Böhme………………………………………. . 133 27. Histological findings of revascularized/revitalized immature permanent molar with apical periodontitis using platelet-rich plasma / By G. Martin, [et al. ]…………………………………… 138 28. Unicystic ameloblastoma mimicking apical periodontitis: a case series / By R. O. Gondak, [et al. ]………… 145

Content: Vol. 39 № 2 2013 г. 1. Association between apical periodontitis and smoking / By R. K. Celeste, M. S. Gomes…………………………………………. … 157 2. Reply to Drs Celeste and Gomes / By J. J. Segura-Egea, [et al. ]…………. … 157 3. Journal of endodontics: new guidelines, new directions / By A. F. Fouad…. …. 159 4. Effect of premedication with ibuprofen and dexamethasone on success rate of inferior alveolar nerve block for teeth with asymptomatic irreversible pulpitis: a randomized clinical trial / By S. Shahi, [et al. ]…………………. . …. … 160 5. Current challenges and concepts of thermomechanical treatment of nickeltitanium instruments / By Y. Shen, [et al. ]……………………. …. … 163 6. Postoperative pain after foraminal enlargement in anterior teeth with necrosis and apical periodontitis: a prospective and randomized clinical trial / By E. J. Silva, [et al. ]…………………………. . . … 173 7. Association between Sickle Cell Anemia and Pulp Necrosis / By C. P. Costa, E. B. Thomaz; F. Souza Sde…. . 177 8. Subclinical failures of direct pulp capping of human teeth by using a dentin bonding system / By G. A. Silva, [et al. ]…………………………………………………………. ……… 182 9. Molecular microbiological evaluation of passive ultrasonic activation as a supplementary disinfecting step: a clinical study / By S. S. Paiva, [et al. ]…………………………………………. … 190 10. Preliminary study on dental pulp stem cell-mediated pulp regeneration in canine immature permanent teeth / By Y. Wang, [et al. ]………………………………………………. … 195 11. Pedialyte promotes periodontal ligament cell survival and motility / By S. Macway-Gomez, T. E. Lallier. … 202 12. The butterfly effect: an investigation of sectioned roots / By А. А. Russell, [et al. ]……………. … 208 13. DNA binding to hydroxyapatite: a potential mechanism for preservation of microbial DNA / By М. Brundin, [et al. ]………………………………………………………. … 211 14. Fluocinolone acetonide promotes the proliferation and mineralization of dental pulp cells / By Z. Liu, [et al. ]……………………………………………………………. . …… 217 15. Increased expression of Eph. A 7 in inflamed human dental pulp / By Y. Dong, [et al. ]…………. … 223 16. Usefulness of controlled release of growth factors in investigating the early events of dentin-pulp regeneration / By S. Mathieu, [et al. ]…………………………………………… 228

17. The survival role of peroxisome proliferator-activated receptor gamma induces odontoblast differentiation against oxidative stress in human dental pulp cells / By Y. H. Lee, [et al. ]…………………. ……. . 236 18. The effect of mineral trioxide aggregate on odontogenic differentiation in dental pulp stem cells / By M. S. Seo, [et al. ]………………………………………………………. …… 242 19. Biofilm formation within the interface of bovine root dentin treated with conjugated chitosan and sealer containing chitosan nanoparticles / By L. Da. Silva, [et al. ]……………………………. . …… 249 20. Self-adjusting file cleaning-shaping-irrigation system improves root-filling bond strength / By G. De-Deus, [et al. ]…………………………………………………………. ……… 254 21. Influence of continuous or reciprocating motion on cyclic fatigue resistance of 4 different nickel-titanium rotary instruments / By Е. Pedullà, [et al. ]……………………………………. . ……… 258 22. Effects of self-adjusting file, Mtwo, and Pro. Taper on the root canal wall / By E. S. Hin, [et al. ]…………. … 262 23. Anatomic study of the buccal root with furcation groove and associated root canal shape in maxillary first premolars by using micro-computed tomography / By J. Li, L. Li, Y. Pan……………………. . . … 265 24. Effect of medicaments used in endodontic regeneration technique on the chemical structure of human immature radicular dentin: an in vitro study / By G. H. Yassen, [et al. ]……………………… 269 25. Evaluation of cytotoxicity and physicochemical properties of calcium silicate-based endodontic sealer MTA Fillapex / By E. J. Silva, [et al. ]…………………………………………… 274 26. Comparative study of 6 rotary nickel-titanium systems and hand instrumentation for root canal preparation in severely curved root canals of extracted teeth / By D. Celik, Т. Taşdemir, К. Er…………………. . . 278 27. Limitations of push-out test in bond strength measurement / By W. P. Chen, [et al. ]…………. …… 283 28. Pulp revascularization of immature dens invaginatus with periapical periodontitis / By J. Yang, [et al. ]… 288

Content: Vol. 39 № 3 2013 г. 1. Anesthetic efficacy of a primary articaine infiltration and a repeat articaine infiltration in the incisive/mental nerve region of mandibular premolars: a prospective, randomized, single-blind study / By A. S. Dressman, [et al. ]……. . … 313 2. Revascularization: a treatment for permanent teeth with necrotic pulp and incomplete root development / By R. Wigler, [et al. ]………………. . … 319 3. Prognostic factors for clinical outcomes according to time after direct pulp capping / By S. Y. Cho, [et al. ]…………………………. . . …… 327 14. Outcomes of surgical endodontic treatment performed by a modern technique: an updated meta-analysis of the literature / By I. Tsesis, [et al. ]………………………………………. . . …… 332 5. Aging of in vitro pulp illustrates change of inflammation and dentinogenesis / By Y. H. Lee, [et al. ]……… 340 6. Comparative analysis of Enterococcus faecalis biofilm formation on different substrates / By J. M. Guerreiro. Tanomaru, [et al. ]………………………………………………………. . 346 7. CD 44 is involved in mineralization of dental pulp cells / By K. L. Chen, [et al. ]………………. . . … 351 8. Characterization of a stem cell of apical papilla cell line: effect of passage on cellular phenotype / By N. B. Ruparel, [et al. ]………………………………………………………. . … 357 9. Efficacy of bacteriophage treatment on Pseudomonas aeruginosa biofilms / By А. Phee, [et al. ]…. . …. ……… 364 10. Collagen-binding streptococcal surface proteins influence the susceptibility of biofilm cells to endodontic antimicrobial solutions / By T. L. Violante, E. M. Haase, М. М. Vickerman………………………. . 370 11. Estimation of the failure risk of a maxillary premolar with different crack depths with endodontic treatment by computer-aided design/computer-aided manufacturing ceramic restorations / By C. L. Lin, [et al. ]…………………………………………………………. . ……… 375 12. Effect of various endodontic irrigants on the push-out bond strength of biodentine and conventional root perforation repair materials / By М. В. Guneser, M. B. Akbulut, A. U. Eldeniz………………. . 380

13. Micro-computed tomography evaluation of the preparation of mesiobuccal root canals in maxillary first molars with Hyflex CM, Twisted Files, and K 3 instruments / By D. Zhao, [et al. ]………………… 385 14. Effect of R-phase heat treatment on torsional resistance and cyclic fatigue fracture / By J. H. Ha, [et al. ]. … 389 15. An in vitro comparison of the accuracy of measurements obtained from high- and low-resolution conebeam computed tomography scans / By D. Hashem, [et al. ]…………………………. . . ……… 394 16. Comparison of the cleaning efficacy of self-adjusting file and rotary systems in the apical third of ovalshaped canals / By M. V. de Melo Ribeiro, [et al. ]…………………………………… 398 17. In vitro assessment of mineral trioxide aggregate setting in the presence of interstitial fluid alone / By L. De. Angelis, [et al. ]………………………………………………………. . 402 18. Dentin inhibits the antibacterial effect of new and conventional endodontic irrigants / By R. D. Morgental, [et al. ]…………………………………………………………. … 406 19. A small amount of singlet oxygen generated via excited methylene blue by photodynamic therapy induces the sterilization of Enterococcus faecalis / By С. Komine, Y. Tsujimoto……………………… 411 20. A clinical report of the management of episodic idiopathic pruritus occurring during endodontic therapy / By Т. А. Montagnese, М. Setty………………………………………………. . 415 21. Pulp revascularization after root canal decontamination with calcium hydroxide and 2% chlorhexidine gel / By J. Soares Ade, [et al. ]………………………………………………. ……… 417

Content: Vol. 39 № 4 2013 г. 1. Reversal of pulpal and soft tissue anesthesia by using phentolamine: a prospective randomized, single-blind study / By S. Elmore, [et al. ]………. . . … 429 2. A cone-beam computed tomography study of the root canal morphology of mandibular first premolars and the location of root canal orifices and apical foramina in a Chinese subpopulation / By Н. Yang, [et al. ]………………. …. . . …… 435 3. Is mandibular molar buccal infiltration a mental and incisive nerve block? A randomized controlled trial / By С. С. Currie, [et al. ]………………. … 439 4. Expression levels of matrix metalloproteinase-9 and gram-negative bacteria in symptomatic and asymptomatic periapical lesions / By G. M. Ahmed , [et al. ]……………………………… 444 5. Different treatment protocols for different pulpal and periapical diagnoses of 72 cracked teeth / By S. Y. Kim, [et al. ]………………………………………………………… 449 6. Th 1 and Th 2 -like protein balance in human inflammatory radicular cysts and periapical granulomas / By С. А. de Carvalho Fraga, [et al. ]……………………………………………… 453 7. Elevated tumor necrosis factor-alpha expression in periapical lesions infected by Epstein-Barr virus / By К. Hernádi, [et al. ]……………………………………………………. …… 456 8. The antioxidant property of pachymic acid improves bone disturbance against AH plus-induced inflammation in MC-3 T 3 E 1 cells / By T. G. Kim, [et al. ]………………………………. . … 461 9. Biological effects and washout resistance of a newly developed fast-setting pozzolan cement / By Y. Choi, [et al. ]……………………………………………………………. … 467 10. Effect of the source of biofilm bacteria, level of biofilm maturation, and type of disinfecting agent on the susceptibility of biofilm bacteria to antibacterial agents / By S. Stojicic, Y. Shen, М. Haapasalo…………. …. …. . 473 11. In Vitro cytotoxicity evaluation of a novel root repair material / By Н. М. Zhou, [et al. ]……………. … 478 12. Coronal tooth discoloration and white mineral trioxide aggregate / By D. Felman, Р. Parashos……. . ……… 484 13. Up-regulation of p 38 mitogen-activated protein kinase during pulp injury-induced glial cell/neuronal interaction in the rat thalamus / By Т. Kaneko, [et al. ]………………………………. . …… 488

14. Methylation pattern of IFNG in periapical granulomas and radicular cysts / By К. Campos, [et al. ]……… 493 15. Biocompatibility of mineral trioxide aggregate mixed with hydration accelerators / By J. Y. Kang, [et al. ]. . 497 16. Incidence of dentinal defects after root canal preparation: reciprocating versus rotary instrumentation / By S. Bürklein, Р. Tsotsis, Е. Schäfer……………………………………………. …… 501 17. Interactions between irrigants commonly used in endodontic practice: a chemical analysis / By М. Prado, [et al. ]…………………………………………………………. …… 505 18. Apical pressure and extent of irrigant flow beyond the needle tip during positive-pressure irrigation in an in vitro root canal model / By Е. Park, [et al. ]……………………………………… 511 19. Comparison of the mechanical properties of rotary instruments made of conventional nickel-titanium wire, M-wire, or nickel-titanium alloy in R-phase / By Н. Р. Lopes, [et al. ]……………………. … 516 20. Effect of needle insertion depth and root canal curvature on irrigant extrusion ex vivo / By Z. Psimma, [et al. ]……………………………………………………………. . … 521 21. Influence of light and oxygen on the color stability of five calcium silicate-based materials / By М. Vallés, [et al. ]…………………………………………………………… 525 22. Periapical pressures developed by nonbinding irrigation needles at various irrigation delivery rates / By S. Khan, [et al. ]………………………………………………………. . …… 529 23. Glide path preparation in S-shaped canals with rotary pathfinding nickel-titanium instruments / By N. C. Ajuz, [et al. ]………………………………………………………. . … 534 24. Intramanufacturer diameter and taper variability of rotary instruments and their corresponding Guttapercha cones / By М. В. Chesler, [et al. ]………………………………………… 538 25. Characterization of dentin matrix biomodified by Galla chinensis extract / By М. Deng, [et al. ]……. . …… 542 26. Intraoperative endodontic applications of cone-beam computed tomography / By R. L. Ball, J. V. Barbizam, N. Cohenca……………………………………………………………. 548

Content: Vol. 39 № 5 2013 г. 1. Management of intracanal separated instruments / By A. A Madarati, M. J Hunter, P. M. Dummer……………………………. …. . 569 2. The significance of epithelial rests of Malassez in the periodontal ligament / By D. Keinan, R. E. Cohen……………………. ……. . 582 3. Second canal in mesiobuccal root of maxillary molars is correlated with root third and patient age: a cone-beam computed tomographic study / By A. G. Reis, [et al. ]……………………………………………… 588 4. Suitability of time estimates for survival analysis of endodontic treatment / By G. S. Cheung, A. H. Lee, M. C. Wong………………. . . ……. 593 5. A prospective, randomized, double-blind comparison of the injection pain and anesthetic onset of 2% lidocaine with 1: 100, 000 epinephrine buffered with 5% and 10% sodium bicarbonate in maxillary infiltrations / By Р. Hobeich, [et al. ]…………………………………………………. …… 597 6. Periradicular status and quality of root canal fillings and coronal restorations in an urban Colombian population / By J. O. Moreno, [et al. ]…………………………………………… 600 7. Localization and signaling patterns of vascular endothelial growth factors and receptors in human periapical lesions / By А. Virtej, [et al. ]………………………………………………. … 605 8. Lymphoid enhancer-binding factor 1 expression precedes dentin sialophosphoprotein expression during rat odontoblast differentiation and regeneration / By М. Nakatomi, Н. Ida-Yonemochi, H. Ohshima………………… 612 9. Simvastatin suppresses osteoblastic expression of Cyr 61 and progression of apical periodontitis through enhancement of the transcription factor Forkhead/winged helix box protein O 3 a / By L. D. Lin, [et al. ]……… 619 10. Mesenchymal stem cells promote hard-tissue repair after direct pulp capping / By М. Obeid, [et al. ]. . …… 626 11. Effect of Enterococcus faecalis lipoteichoic acid on apoptosis in human osteoblast-like cells / By Y. Tian, [et al. ]……………………………………………………………. … 632 12. Expression and regulation of a disintegrin and metalloproteinase-8 and -17 in development of rat periradicular lesion / By Т. Tanaka, [et al. ]……………………………………. ……… 638 13. Outcome of periapical lesions in a rat model of type 2 diabetes: refractoriness to systemic antioxidant therapy / By C. F. Wolle, [et al. ]……………………………………………. …… 643

14. Periapical lesions decrease insulin signal and cause insulin resistance / By R. D. Astolphi, [et al. ]………. … 648 15. Tissue reactions to a new mineral trioxide aggregate-containing endodontic sealer / By С. О. Tavares, [et al. ]……………………………………………………………. … 653 16. A comparative study of biofilm removal with hand, rotary nickel-titanium, and self-adjusting file instrumentation using a novel in vitro biofilm model / By J. Lin, Y. Shen, М. Haapasalo…………………. . …. …. 658 17. Detection of para-chloroaniline, reactive oxygen species, and 1 -chloro-4 -nitrobenzene in high concentrations of chlorhexidine and in a mixture of chlorhexidine and calcium hydroxide / By L. E. Barbin, [et al. ]……………………………………………………………. …. … 664 18. Critical evaluation of the push-out test for root canal filling materials / By E. S. Pane, J. E. Palamara, Н. Н. Messer…………………………………………………………. …. …. 669 19. The effect of MTADN on 10 Enterococcus faecalis isolates and biofilm: an in vitro study / By Z Tong, [et al. ]…………………………………………………………. …. …… 674 20. Electrochemical dissolution of nickel-titanium endodontic files induces periodontal ligament cell death / By Q Mitchell, [et al. ]…………………………………………………. . …. … 679 21. Effect of altering the reciprocation range on the fatigue life and the shaping ability of Wave. One nickeltitanium instruments / By D. Saber Sel, S. M. , Abu El Sadat……………………………… 685 22. Effect of different irrigation protocols on resin sealer bond strength to dentin / By М. Prado, R. A. Simão, B. P. Gomes…………………………………………………………… 689 23. Fatigue Life of Reciproc and Mtwo instruments subjected to static and dynamic tests / By Н. Р. Lopes, [et al. ]……………………………………………………………. . … 693 24. Effect of blood contamination on the retention characteristics of two endodontic biomaterials in simulated furcation perforations / By S. Rahimi, [et al. ]……………………………………. . 697 25. Influence of dentin from the root canal walls and the pulp chamber floor on the p. H of intracanal medicaments / By А. Agrafioti, N. E. Tzimpoulas, E. G. Kontakiotis…………………………. . . … 701 26. Influence of the geometry of curved artificial canals on the fracture of rotary nickel-titanium instruments subjected to cyclic fatigue tests / By Н. Р. Lopes, [et al. ]………………………………. . … 704 27. Comparison of Vibringe, Endo. Activator, and needle irrigation on sealer penetration in extracted human teeth / By J. A. Bolles. [et al. ]……………………………………………. . …… 708 28. Exuberant Biofilm infection in a lateral canal as the cause of short-term endodontic treatment failure: report of a case / By D. Ricucci, S. Loghin, J. F. Siqueira Jr………………………………. … 712

29. Regenerative endodontic treatment of an immature permanent tooth at an early stage of root development: a case report / By Х. Chen, [et al. ]…………………………………………… 719