Bioinformatics Center of Expertise Jelle Goeman
What is Bioinformatics? Medicine Computer Science Bioinformatics Biology Statistics Bioinformatics: Analyzing and connecting data from high throughput molecular biology and imaging Bioinformatics Center of Expertise 2 10 November 2009
High throughput Modern technologies produce massive amounts of data Bioinformatics Center of Expertise 3 10 November 2009
Connecting and analyzing • Analyzing: statistical and computational analysis, experimental design • Connecting: with databases (web), literature, making data accessible Bioinformatics Center of Expertise 4 10 November 2009
Bioinformatics at the LUMC Many departments have moved into bioinformatics Medical Statistics Statistical bioinformatics Molecular Epidemiology Genetic population studies Human Genetics Bioinformatics of genomics Molecular Cell Biology Bioinformatics of imaging Parasitology Bioinformatics of proteomics Medical Microbiology Virology bioinformatics Pathology Bioinformatics of tumor genomics … more departments expected to follow Bioinformatics Center of Expertise 5 10 November 2009
The Bioinformatics Center of Expertise Joins together all bioinformaticians of the whole LUMC to 1. Make Bioinformatics expertise available to the whole LUMC 2. Exchange knowledge and facilitate cooperation between bioinformaticians 3. Organize courses in bioinformatics (researchers/students) A “virtual department” Bioinformatics Center of Expertise 6 10 November 2009
Participants of the Center of Expertise Available to be consulted in their area of expertise Human Genetics • Judith Boer • Peter-Bram ‘t Hoen • Jan Bert van Klinken • Barend Mons • Marco Roos • Peter Taschner Medical Statistics and Bioinformatics • Stefan Böhringer • Bas Heijmans • Jeanine Houwing • Joost Kok • Bart Mertens • Kai Ye • Erik van Zwet Medical Microbiology • Sasha Gorbalenya • Igor Sidorov Pathology • Ronald van Eijk • Jan Oosting Molecular Cell Biology • Raimond Ravelli • Willem Sloos • Hans Vrolijk Bioinformatics Center of Expertise Parasitology • Yuri van der Burgt • Magnus Palmblad 7 10 November 2009
How to find the expert you need? www. lumc. nl/bioinformatics Bioinformatics Center of Expertise 8 10 November 2009
The core OR: contact the core of the Center to be forwarded The core of the Center of Expertise • Jelle Goeman Coordinator, statistical aspects of bioinformatics • Scott Marshall Computer science aspects of bioinformatics • Ramin Monajemi Scientific programmer Bioinformatics Center of Expertise 9 10 November 2009
Schematic organization Users Bioinformaticians Core Participants Bioinformatics Center of Expertise 10 10 November 2009
What to expect? Consulting: two flavors 1. Advice • Expert opinion • Be pointed to software, references, courses, people 2. Scientific Collaboration • Regular advice throughout the project • Performing analyses What to give in return? • Consulting is free for all LUMC researchers • Collaborations should be rewarded with co-authorships Model: statistical consulting Bioinformatics Center of Expertise 11 10 November 2009
Seminar series Integrated data analysis in Epidemiology and Bioinformatics • Speakers from inside and outside LUMC • Broad range of subjects; broad audience; practical perspective • Integrated with • Human Genetics Genomics/Bioinformatics seminars • Genetic Epidemiology Theme Group • Organizers: Eline Slagboom, Judith Boer, Joost Kok, Jeanine Houwing, Jelle Goeman • Every 2 weeks on Tuesday 15: 45 • More information on www. lumc. nl/bioinformatics Bioinformatics Center of Expertise 12 10 November 2009
Education and Teaching • Courses for researchers • Keep track of available courses (also elsewhere) • Jointly teach courses • MGC courses microarrays/nextgen sequencing (Judith Boer) • Set up new courses if necessary • Projects for students • Hogeschool Bioinformatica • Delft/LIACS Bioinformatics master • Moscow State University (Sasha Gorbalenya) Bioinformatics Center of Expertise 13 10 November 2009
Under development: the bioinformatics wiki www. bioexp. org (under construction) wiki: a web site that every LUMC researcher can read and edit • A fountain of information on bioinformatics • What courses to follow • What tools to use • A virtual coffee machine • Meet bioinformaticians • Discuss bioinformatics Bioinformatics Center of Expertise 14 10 November 2009
A Bioinformatics Center of Expertise Bioinformatics • Much expertise available at the LUMC • Added value in cooperation A Center of Expertise • Make knowledge of bioinformatics more easily available • Help all LUMC researchers to the right expertise quickly • Stimulate exchange between bioinformaticians Bioinformatics Center of Expertise 15 10 November 2009
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