Architecting the Virtual Organisation Drug Discovery Process

Architecting the Virtual Organisation

Drug Discovery Process

Informatics links the information used to find and validate new targets

R&D Strategy: Virtualisation

R&D Strategy: Globalisation

Challenge for IT in GSK

IT Techniques needed to support this transition

Business Process Modelling & Model Driven Design

Request System Request Product Inventory System Build Product QC System QC Product Delivery System Deliver Product Process Monitor (captures metrics)

Use of Information Architecture

Workflow Analysis

Why Workflow ?

Target Application Architecture Sequencing LIMS micro. Array LIMS Proteomics LIMS Cellular LIMS Metabolomics LIMS

Biology Target Architecture Goals

Demonstrators in the portfolio space

Portfolio support using Workflow and Semantic Grid

Concept Capture

Target Management

Drug Discovery Process (again) Request System Inventory System QC System Delivery System

1. Workflow in reagent tracking POC

Workflow challenges for Production Status

2. Semantic Grid for Portfolio POC

Assay Validation Analysis X

Business Value ? ?

GRID Challenges in Industry

One such group is SIMDAT

What is SIMDAT ?

SIMDAT - Overview

Drivers for joining SIMDAT

GSK architectural Direction Security Payment Continuity Value

First B 2 B Scenario

SIMDAT gives us

Implemented Components of the B 2 B Scenario Job execution Annotate project portal User Workflow Infor. Sense KDE Updating SB Job execution

Final Scenario; B 2 A

In Conclusion

Acknowledgements