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An Interactive Virtual Endoscopy Tool With Automated Path Generation Delphine Nain, MIT AI Laboratory. An Interactive Virtual Endoscopy Tool With Automated Path Generation Delphine Nain, MIT AI Laboratory. Thesis Advisor: W. Eric. L Grimson, MIT AI Laboratory.

Presentation Overview • Background and Motivation • Interactive System • Central Path Planning Algorithm Presentation Overview • Background and Motivation • Interactive System • Central Path Planning Algorithm • Synchronized Virtual Endoscopy • Conclusion

Medical Motivation • Cancer is the 2 nd cause of death in the US Medical Motivation • Cancer is the 2 nd cause of death in the US • 43 % of people have a risk to be diagnosed with cancer – Out of those 88 % are cancer in inner organ • How can “see” inside the body to screen and cure?

Conventional Endoscopy • advantages: – minimally invasive – high resolution – interactivity • disadvantages: Conventional Endoscopy • advantages: – minimally invasive – high resolution – interactivity • disadvantages: –can be painful and uncomfortable –limited exploration

Conventional Medical Imaging Conventional Medical Imaging

Conventional Visualization • advantages: – non invasive – information on tissue shape through and Conventional Visualization • advantages: – non invasive – information on tissue shape through and beyond walls of organ • disadvantages: –mentally align contiguous slides –lower resolution than video

Segmentation: Volume Segmentation: Volume

3 D Reconstruction : Model 3 D Reconstruction : Model

3 D Visualization 3 D Visualization

Virtual Endoscopy • Combines strengths of previous alternatives on patient-specific dataset – Spatial exploration Virtual Endoscopy • Combines strengths of previous alternatives on patient-specific dataset – Spatial exploration – Cross-correlation with original volume Compact and Intuitive way to explore huge amount of information

Virtual Endoscopy: advantages • clinical studies: – planning and post-operation: generates views that are Virtual Endoscopy: advantages • clinical studies: – planning and post-operation: generates views that are not observable in actual endoscopic examinations – color coding algorithms give supplemental information

Virtual Colonoscopy Virtual Colonoscopy

System Requirements • Combination of Interactivity and Automation is key • Cross Reference between System Requirements • Combination of Interactivity and Automation is key • Cross Reference between 3 D models and grayscale volumes

Presentation Overview • Background and Motivation • Interactive System • Central Path Planning Algorithm Presentation Overview • Background and Motivation • Interactive System • Central Path Planning Algorithm • Synchronized Virtual Endoscopy • Conclusion

Display Display

Navigation Interface Navigation Interface

Cross Reference Provided by Arjan Welmers Cross Reference Provided by Arjan Welmers

Path: Update Path: Update

Applications: Middle Ear Thomas Rodt Soenke Bartling Applications: Middle Ear Thomas Rodt Soenke Bartling

Applications: Cardiovascular Provided by Bonglin Chung Applications: Cardiovascular Provided by Bonglin Chung

Presentation Overview • Background and Motivation • Interactive System • Central Path Planning Algorithm Presentation Overview • Background and Motivation • Interactive System • Central Path Planning Algorithm • Synchronized Virtual Endoscopy • Conclusion

Automated Path Planning • Goal: provide a “create path” button that produces a centerline Automated Path Planning • Goal: provide a “create path” button that produces a centerline inside a 3 D model of any topology

Input Input

Output Output

Step 1: Produce a Labelmap Step 1: Produce a Labelmap

Step 2: Produce a distance map Step 2: Produce a distance map

Step 3: Create a Graph description of the Distance Map • Nodes are voxels Step 3: Create a Graph description of the Distance Map • Nodes are voxels inside the model • Edge weight are 1/(distance)2 from the wall of the organ

Step 4: Run modified Dijkstra algorithm is a single source shortest path algorithm • Step 4: Run modified Dijkstra algorithm is a single source shortest path algorithm • We use a binary heap • An optimization: keep an evolving front, stop when reach the end node

Step 5: Results Running Time: ~7 s Step 5: Results Running Time: ~7 s

Step 5: Results Running Time: ~3 s Step 5: Results Running Time: ~3 s

Presentation Overview • Background and Motivation • Interactive System • Central Path Planning Algorithm Presentation Overview • Background and Motivation • Interactive System • Central Path Planning Algorithm • Synchronized Virtual Endoscopy • Conclusion

Synchronized Virtual Colonoscopy Synchronized Virtual Colonoscopy

Dynamic Programming Dynamic Programming

Results Results

Conclusion • Combination of Automation and Interactivity is key • Cross Reference is important Conclusion • Combination of Automation and Interactivity is key • Cross Reference is important • Synchronized Fly-Throughs is novel contribution Publication: D. Nain, S. Haker, E. Grimson, R. Kikinis “An Interactive Virtual Endoscopy Tool”, IMIVA workshop, MICCAI 2001.

Acknowledgements • • • • Ron Kikinis Steve Haker Lauren O’Donnell David Gering Carl-Fredrik Acknowledgements • • • • Ron Kikinis Steve Haker Lauren O’Donnell David Gering Carl-Fredrik Westin Peter Everett Sandy Wells Eric Cosman Polina Golland Soenke Bartling John Fisher Mike Halle Ferenc Jolesz

Thank You! Steve Haker, Hoon Ji, Connie Sehnert Thank You! Steve Haker, Hoon Ji, Connie Sehnert

Correspondance VC = T is transformation matrix (translation or rotation along local axis) To Correspondance VC = T is transformation matrix (translation or rotation along local axis) To uniquely determine the coordinates of the virtual camera: • coordinates of camera: VCnew = VCold * T • coordinates of the focal point: FPnew = VCnew * T

Cross Reference Provided by Arjan Welmers Cross Reference Provided by Arjan Welmers

3 D Visualization 3 D Visualization

Synchronized Virtual Endoscopy Synchronized Virtual Endoscopy