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An Innovative Approach to Improved Pig Health and Farmer Profitability THE PROBIOTIC CONCEPT Composed An Innovative Approach to Improved Pig Health and Farmer Profitability THE PROBIOTIC CONCEPT Composed by: Eric van den Heuvel 8 th April 2014 The Probiotic Concept Delivered by: Dan Kirschner info@pro-b. ie

Agenda *What’s new/innovative *Principles behind it *Product Range/ Application *Benefits Farmer Profitability – profit Agenda *What’s new/innovative *Principles behind it *Product Range/ Application *Benefits Farmer Profitability – profit Centre Pig Welfare *Case Study *Questions The Probiotic Concept

* Meet my family Eric van den Heuvel (50 yrs) Married with Ine (51 * Meet my family Eric van den Heuvel (50 yrs) Married with Ine (51 yrs) 3 Children Gert (24 yrs) Marieke (18 yrs) Eveline (12 yrs) The Probiotic Concept

GROTE HEIDE 500 sows, built in 1992 Nistelrode The Probiotic Concept GROTE HEIDE 500 sows, built in 1992 Nistelrode The Probiotic Concept

Innovation in Pig Farming Eric van den Heuvel Dan Kirschner The Probiotic Concept Innovation in Pig Farming Eric van den Heuvel Dan Kirschner The Probiotic Concept

Using Probiotic as a Cleaning Agent to: *Control pathogens – Reduced mortality *Improved Food Using Probiotic as a Cleaning Agent to: *Control pathogens – Reduced mortality *Improved Food to Weight conversion – Improved Profitability *Reduced Odours – Better Environment *Reduced Antibiotics – Improve quality The Probiotic Concept

Principle behind this Probiotic Concept Or How does it work? Eric van den Heuvel Principle behind this Probiotic Concept Or How does it work? Eric van den Heuvel Dan Kirschner The Probiotic Concept

Three Core Products Desired and undesired bacteria Adding desired bacteria In the house Cleaner: Three Core Products Desired and undesired bacteria Adding desired bacteria In the house Cleaner: • Detergent + • Probiotic bacteria The Probiotic Concept Spray: • Probiotic bacteria only In the drinking lines Drinking lines cleaner: Probiotic bacteria only

Old system: Bacteria are being killed Chemical detergent Antibiotics Disinfection Result: Resistance of pathogenic Old system: Bacteria are being killed Chemical detergent Antibiotics Disinfection Result: Resistance of pathogenic bacteria!!! For example MRSA, ESBL, Ehec Bacteria The Probiotic Concept

We should start controlling bacteria Biofilm In the farm The Probiotic Concept In the We should start controlling bacteria Biofilm In the farm The Probiotic Concept In the drinking lines

What happens with the use of disinfectants and/or the use of antibiotics? Desired and What happens with the use of disinfectants and/or the use of antibiotics? Desired and undesired bacteria The Probiotic Concept Most resistant bacteria remain Lot’s of space to grow

Control Bacteria with the Probiotic Concept Desired and undesired bacteria The Probiotic Concept Adding Control Bacteria with the Probiotic Concept Desired and undesired bacteria The Probiotic Concept Adding desired bacteria No room for undesired bacteria to develop

Cleaning the drinking lines: Dosing 1: 10, 000 all drinking lines Cleaning the drinking lines: Dosing 1: 10, 000 all drinking lines

Cleaning the house and sow: - remove bulky dirt - foam and wait for Cleaning the house and sow: - remove bulky dirt - foam and wait for a few minutes - wash with high pressure - normally no need for disinfecting - wash the sow (M v A? ) Note: Foam without protective clothing The Probiotic Concept

Maintain healthy microflora by spraying the bacteria regularly throughout the farm. Frequent may vary! Maintain healthy microflora by spraying the bacteria regularly throughout the farm. Frequent may vary! The Probiotic Concept

Benefits Eric van den Heuvel Dan Kirschner The Probiotic Concept Benefits Eric van den Heuvel Dan Kirschner The Probiotic Concept

Visual Results Further more, Hardly No Smell (sorry can’t demonstrate)! The Probiotic Concept Visual Results Further more, Hardly No Smell (sorry can’t demonstrate)! The Probiotic Concept

Floor and wall measurements Stafylococcus Aureus: Date: 2 -3 -2010 6 -5 -2010 9 Floor and wall measurements Stafylococcus Aureus: Date: 2 -3 -2010 6 -5 -2010 9 -9 -2010 CFU 20 1 0 CFU 52 5 0 CFU 15 7 0 CFU 66 1 0 CFU 100 1 0 CFU: Colony Forming Units The Probiotic Concept

Drinking lines lab results Kewi Services Sampledate: 05/08/2011 Date Result: 22/08/2011 Barn: Room: 3 Drinking lines lab results Kewi Services Sampledate: 05/08/2011 Date Result: 22/08/2011 Barn: Room: 3 Report: Animal: Weaned pig Sample taken from: Nipple Description: Flushed: yes Total bacteria count 60. 000 Yeast 0 Mould 0 Enterococcus 0 Stafylococcus not shown Streptococcus not shown MRSA not shown E-coli not shown Clostridium not shown BRMO not shown The Probiotic Concept CFU/ml CFU/ml CFU/ml

Technical Results Grote Heide: 500 sows Piglets born alive per acouchement Pigs weaned per Technical Results Grote Heide: 500 sows Piglets born alive per acouchement Pigs weaned per sow/year Discards before weaning Discards after weaning 2008 14, 5 30, 0 16, 4% 1, 5% 2009 14, 6 30, 8 14, 6% 1, 3% 2010 14, 8 30, 8 14, 9% 1, 6% 2011 14, 7 31, 0 12, 8% 2, 0% In addition we note improvement in weight gain and FCR The Probiotic Concept

The Probiotic Concept The Probiotic Concept

Better health for human, animal and environment A total concept with many advantages Lower Better health for human, animal and environment A total concept with many advantages Lower risk to get MRSA and other zoonoses Hardly antibiotics needed No disinfectants needed Less smell Less dust Reduction of ammonia Less endotoxins The Probiotic Concept

Happy Animals Yield More Managing health with respect for human, animal and environment The Happy Animals Yield More Managing health with respect for human, animal and environment The Probiotic Concept

Where else is the Probiotic Concept implemented Hotels Nurseries Trains Gyms The Probiotic Concept Where else is the Probiotic Concept implemented Hotels Nurseries Trains Gyms The Probiotic Concept Chicken farms

Case Study Eric van den Heuvel Dan Kirschner The Probiotic Concept Case Study Eric van den Heuvel Dan Kirschner The Probiotic Concept

* Meet my family Eric van den Heuvel (50 yrs) Married with Ine (51 * Meet my family Eric van den Heuvel (50 yrs) Married with Ine (51 yrs) 3 Children Gert (24 yrs) Marieke (18 yrs) Eveline (12 yrs) The Probiotic Concept

*October 2003 daughter Eveline planned to have 2 nd open heart surgery *Due to *October 2003 daughter Eveline planned to have 2 nd open heart surgery *Due to life threatening situation Eveline had to be operated 3 months later *With pre-operation check: MRSA positive *Result: being sent home and no operation The Probiotic Concept

The beginning of the MRSA problems Wait, wait… The Probiotic Concept The beginning of the MRSA problems Wait, wait… The Probiotic Concept

We get two weeks to become MRSA free Wash with Hibiscrub 3 x per We get two weeks to become MRSA free Wash with Hibiscrub 3 x per week Nasal ointment bactroban 2 x per day Mouth/throat wash corsodyl 4 x per day The Probiotic Concept

Finally 14 days later she can be operated The Probiotic Concept Finally 14 days later she can be operated The Probiotic Concept

STRAIN DETERMINATION Every hospital has its own strain. The strain of Eveline was not STRAIN DETERMINATION Every hospital has its own strain. The strain of Eveline was not traceable! Where does this MRSA strain come from? 1 st name: NT-MRSA Microbiologist: Dr. Andreas Voss The Probiotic Concept

Samples tested for MRSA. December 2004 25 pig farmers from study group 5 positive. Samples tested for MRSA. December 2004 25 pig farmers from study group 5 positive. This is 20% Dutch population lower than 0, 1% ! Conclusion: There seems to be a connection between MRSA prevalence and pigs. The Probiotic Concept

NT MRSA Pig MRSA Animal related MRSA ST 398 The Probiotic Concept NT MRSA Pig MRSA Animal related MRSA ST 398 The Probiotic Concept

 M Measurements RSA in the family PERSON Mrt '10 Jun '10 Okt '10 M Measurements RSA in the family PERSON Mrt '10 Jun '10 Okt '10 Mrt '11 Aug '11 Okt '11 Jan ‘ 12 Apr ‘ 12 Jul ‘ 12 ERIC POS POS NEG NEG POS NEG INE POS NEG NEG POS NEG GERT POS NEG NEG POS MARIEKE NEG NEG NEG EVELINE POS NEG NEG NEG The Probiotic Concept Okt ‘ 12 Jan ‘ 13 Mei ‘ 13 Aug ‘ 13 NEG NEG POS NEG NEG NEG NEG NEG NEG NEG Nov ’ 13

Thank you for your attention Eric van den Heuvel Dan Kirschner The Probiotic Concept Thank you for your attention Eric van den Heuvel Dan Kirschner The Probiotic Concept info@pro-b. ie