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09 Blood & Lymph Vessels.ppt

  • Количество слайдов: 21

Stephen E. Fish, Ph. D. Mitchell L. Berk, Ph. D. Marshall University J. C. Stephen E. Fish, Ph. D. Mitchell L. Berk, Ph. D. Marshall University J. C. E. School of Medicine

Note to instructors: I use these Power. Point slides in histology lectures that I Note to instructors: I use these Power. Point slides in histology lectures that I give to first year medical students. Copy the slides, or just the images into your own teaching media. We all know that teaching science often requires compromises and simplification for specific student populations, or the requirements of a specific course. Please feel free to offer suggestions for improvements, corrections, or additional illustrations. I would be pleased to hear from anyone who finds my work useful, and am always willing to make it better. Also, the images have been compressed to screen resolution to keep Power. Point file size down, and I can provide them at any resolution. Contact me about the illustrations and Mitchell L. Berk about the photomicrographs. Stephen E. Fish, Ph. D. [email protected] edu [email protected] edu

Blood & lymph vessels Blood & lymph vessels

Vessels have a common plan of layers Vessels have a common plan of layers

A little about elastin in the media • It is made by the smooth A little about elastin in the media • It is made by the smooth muscle cells • Elastin fibers predominate in small arteries • Elastic laminae predominate in large arteries – They are like inner tubes, one inside another – But they are perforated to allow access to O 2 & nutrients – They appear wrinkled in most slides because the smooth muscle often contracts in death

Very large arteries- aorta Artifactual crack Intima Adventitia Media Vasa vasorum Very large arteries- aorta Artifactual crack Intima Adventitia Media Vasa vasorum

Aorta detail This is so dark because it is stained for elastin (Intima is Aorta detail This is so dark because it is stained for elastin (Intima is missing on many slides) Intima Internal elastic lamina hard to see, look for others in the media Endothelium Media

Dense irregular CT of adventitia with elastic stain Aorta detail Media Vasa vasorum Crack Dense irregular CT of adventitia with elastic stain Aorta detail Media Vasa vasorum Crack External elastic lamina

Muscular arteries (medium size) Media- elastic lamina faint or nonexistent, mostly elastin fibers Intima Muscular arteries (medium size) Media- elastic lamina faint or nonexistent, mostly elastin fibers Intima very thin Internal elastic lamina Adventitia

Arterioles • Minimal intima & 1 - 3 muscle layers • In media a Arterioles • Minimal intima & 1 - 3 muscle layers • In media a few elastin fibers & no laminae • Normal constriction (vasomotor response) is important for regulating capillary blood flow

Capillaries supplying sweat glands with water & proteins • Capillaries consist of endothelial cells Capillaries supplying sweat glands with water & proteins • Capillaries consist of endothelial cells & their basement membrane • The only layer is the intima

Type 1 Capillary Type 1 Capillary

Type 2 (for type 3, covered in kidney lectures, just imagine there are no Type 2 (for type 3, covered in kidney lectures, just imagine there are no diaphragms)

One example of a sinusoid One example of a sinusoid

Capillary bed Capillary bed

Low flow (pressure) in a capillary bed Low flow (pressure) in a capillary bed

High flow in a capillary bed High flow in a capillary bed

Lymphatic vessels Lymphatic vessels

Medium artery & vein compared Medium artery & vein compared

How veins look on slides How veins look on slides

Vena cava Vena cava