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Kazakh National Medical University named after S. J. Asfendiyarov Departament of foreign languages Theme: Kazakh National Medical University named after S. J. Asfendiyarov Departament of foreign languages Theme: Rheumatic endocarditis Checked by: Bayanbaeva A. A. Done by : Sabit B. M. General medicine 14 -008 -2 k Almaty 2015 -2016 y

Rheumatism (Sokolsky-Bouillaud disease) is the infectiously-allergic disease which is characterized by system disorganization of Rheumatism (Sokolsky-Bouillaud disease) is the infectiously-allergic disease which is characterized by system disorganization of connecting tissue with the dominant defeat of the heart-vessels system. An exciter is the β-haemolitic streptococcus of group A. 1 -3 % of peoples which had streptococci quinsies will be ill by rheumatism. This mean that is the inclination coupled with X-chromosome. 2

Clinico-morphologic forms of rheumatism cardiovascular; polyarthritic; nodular; cerebral. 3 Clinico-morphologic forms of rheumatism cardiovascular; polyarthritic; nodular; cerebral. 3

Cardiovascular form of rheumatism Endocarditis: valvular, chordal, atparietal; acute diffuse, acute warty, fibroplastic, relapsing Cardiovascular form of rheumatism Endocarditis: valvular, chordal, atparietal; acute diffuse, acute warty, fibroplastic, relapsing warty Myocarditis: granulomatic (nodular productive), diffuse interstitial exudative, focal interstitial exudative. Pericarditis: serous, serofibrinous, fibrinous. Vasculitis: capillaritis, arteriolaritis, arteritis. 4

Rheumatic endocarditis Endocarditis associated with rheumatic fever. Involvement may be mural but is usually Rheumatic endocarditis Endocarditis associated with rheumatic fever. Involvement may be mural but is usually valvular and involves the entire valve; It is then more accurately termed rheumatic valvuliatis.

Endocarditis 6 Endocarditis 6

Symptoms Symptoms include: Fever, chills; Weakness, low energy; Sweatiness, especially at night; Shortness of Symptoms Symptoms include: Fever, chills; Weakness, low energy; Sweatiness, especially at night; Shortness of breath; Cough; Loss of appetite, body weight;

 Chest pain; Abdominal pain; Nausea and vomiting; Painful red patches on the fingres Chest pain; Abdominal pain; Nausea and vomiting; Painful red patches on the fingres

Diagnostics Examination of suspected infective endocarditis includes a detailed examination of the patient, and Diagnostics Examination of suspected infective endocarditis includes a detailed examination of the patient, and especially careful cardiac auscultation; various blood tests; ECG; Echocardiography.

Pathological changes: early stage: serous endocarditis , valve swelling, translucent Microscopically: valve become loose Pathological changes: early stage: serous endocarditis , valve swelling, translucent Microscopically: valve become loose due to serous exudate , accompanied by macrophages entering and fibrinoid necrosis of collagen fiber. Concomitant involvement of the endocardium and the leftsided valves by inflammatory foci typically results the small (diameter 1 - to 2 -mm) vegetations.

Acute rheumatic endocarditis: small (diameter 1 - to 2 -mm) vegetations along the mitral Acute rheumatic endocarditis: small (diameter 1 - to 2 -mm) vegetations along the mitral valve margin, insufficient to cause valvular deformation.

Mitral stenosis with diffuse fibrous thickening and distortion of the valve leaflets, commissural fusion Mitral stenosis with diffuse fibrous thickening and distortion of the valve leaflets, commissural fusion (arrows), and thickening and shortening of the chordae tendineae.

Small vegetations (verruca) are visible along the line of closure of the mitral valve Small vegetations (verruca) are visible along the line of closure of the mitral valve leaflet (arrows).

Glossary Эндокардит Endocardit Ревматикалық Ревматический Rheumatic Әлсіздік Слабость Weakness Терлегіштік Потливости Sweatiness Жөтел Кашель Glossary Эндокардит Endocardit Ревматикалық Ревматический Rheumatic Әлсіздік Слабость Weakness Терлегіштік Потливости Sweatiness Жөтел Кашель Cough Жүрек айну Тошнота Nausea Сырқырау Озноб Chill Эхокардиография Echocardiography. Қақпақша Клапан Valvular Хорда Chordal

Spent literature 1)“Essential english for medical students” A. M. Maslova, Z. I. Winestein, L. Spent literature 1)“Essential english for medical students” A. M. Maslova, Z. I. Winestein, L. S. Plebeys kaya 2)www. google. com 3)www. medicine. com

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