Department of Foreign Languages Belarusian State Medical University, Minsk CELL TECHNOLOGIES IN HEMATOLOGY AS THE METHOD NEUTROPENIA TREATMENT Irina Belyavskaya, 2206 group The pediatric faculty, 2 year. Supervisor: Tikhonovitch Irina Ivanovna
Objective • To review the publications about Cell technologies in Hematology during chemotherapy-induced neutropenia.
Materials and methods • We analyzed scientific articles on the topic of сell technologies in hematology, using of antibacterial, antifungal and antiviral drugs.
Introduction • Neutropenia is one of the complications of cytotoxic chemotherapy in patients with hematologic malignancies, which may lead to death. To solve the problem antibiotic therapy is introdused
Chemotherapy Neutropenia Infections
Common presenting symptoms of neutropenia include the following:
Miscellaneous agents Antitumor antibiotics: Anthracyclines, anthracene derivatives Anthracenedione derivatives Miscellaneous compounds Methotrexate Alkylating agents Antimetabolites Vinca alkaloids Podophyllotoxin derivates Chemotherapeutic agents used in the treatment of hematologic malignancies
The course of neutropenia and its complications
Different patients are at different risk of acquiring neutropenia
Neutropenia may occur in case of the following hematological malignancies Myeloid Neoplasms Lymphoid Neoplasms Posttransplant Lymphoproliferative Disorders
Infectious agents Protozoas • Bacteria • Fungi • Viruses Helminthes
Factors of neutropenia development
To access blood from neutropenia the samples are freezed and then placed to the cryobank
antifungal antiviral
Antiviral drugs Foscarnet Ganciclovir
Cell technologies in hemotology
In development:
Further development of diagnostic techniques and successful treatment of patients with neutropenia, genetic, immune, haematological and oncological diseases require deeper scientific knowledge and new, more reliable methods of evidence-based medicine.
Thank you for your attention!
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